TCONS_00066421-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00066421-protein
Unique Name	TCONS_00066421-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	622

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00066421-protein ID=TCONS_00066421-protein|Name=TCONS_00066421-protein|organism=Clytia hemisphaerica|type=polypeptide|length=622bp
MELCNSGFLFLYSQSKVQSLLITKDSPIDKDLQKLKEVASVDINIEQLLV
VPAYSEVGDDVIALFCLFNKIGAKTGFTKLDEELMQMVVKNCRHIVCNAL
DWKSQLIIQRQNESLLEISKTLFSHLDDVSILLHKIMEEARNLTNAERCS
LFLVDHNRGELIAKVFDGIESENSSEIRIPITNGIAGYVATTGETLNIKD
AYSHPLFYKEVDQKTGFKTRHILCFPIRSVSEQIIGVAQLCNKLNGNCFT
KFDEERTLGFAIFVGLSLVQSLLYKKATDAKQRSKLANELMLYHMMVSQE
EIDSYVKVAMPTKDSLHPDMDKFSFMPRISFAETDSIKVVLSMFNDLNVI
KRWKVSESTLVRFILTVRRGYRDVPYHNWTHAWTVAHFSYTLLKKTNALD
YLSDLEVFVLLVSCLCHDIDHRGTNNSFQISSQSVLASLYSSAGSVLERH
HFAQAMCIVQTEHNNVFESLSSTDYKRALDLMQKMILATDLANHFKISKQ
LDELASTGIQKDEAAHRELLLSLFMTTSDLSDQTKPWESAVKVSDLLYQE
FFSQGEMEKSLGYQPVKMMDKDLASIPDLQYSFLNNIAYPIYEKLSHFFP
ETNCILGNIKENQKQWSKIKEG

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041561	XLOC_041561	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00066421	TCONS_00066421	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR003018	GAF
IPR029016	GAF_dom-like
IPR002073	PDEase_catalytic_dom
IPR023174	PDEase_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0005515	protein binding
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function	GO:0008081	phosphoric diester hydrolase activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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POSITION

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 542..558 score: 42.59 coord: 403..416 score: 32.29 coord: 417..432 score: 61.0 coord: 372..385 score: 54.0 coord: 525..538 score: 53.71 coord: 445..461 score: 45.06
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 374..543 e-value: 3.1E-9 score: 46.7
IPR003018	GAF domain	SMART	SM00065	gaf_1	coord: 128..278 e-value: 1.7E-34 score: 130.6
IPR003018	GAF domain	PFAM	PF01590	GAF	coord: 130..266 e-value: 4.9E-14 score: 53.0
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 18..92 e-value: 0.086 score: 12.3
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 108..292 e-value: 1.8E-35 score: 121.8
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 42..127
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 109..294
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 376..609 e-value: 7.8E-76 score: 254.8
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	GENE3D	1.10.1300.10		coord: 295..622 e-value: 2.0E-102 score: 342.1
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I	coord: 417..428
None	No IPR available	CDD	cd00077	HDc	coord: 376..552 e-value: 3.18329E-14 score: 69.2905
None	No IPR available	SUPERFAMILY	109604	HD-domain/PDEase-like	coord: 313..621

Blast

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BLAST of TCONS_00066421-protein vs. Swiss-Prot (Human)
Match: PDE2A (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Homo sapiens GN=PDE2A PE=1 SV=1)

HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0
Identity = 285/591 (48.22%), Postives = 416/591 (70.39%), Query Frame = 0

Query:   30 KDLQKLKEVASVDINIEQLLVVPAYSEVGDDVIALFCLFNKIGAKTGFTKLDEELMQMVVKNCRHIVCNALDWKSQLIIQRQNESLLEISKTLFSHLDDVSILLHKIMEEARNLTNAERCSLFLVDHNRGELIAKVFDG-IESENSSEIRIPITNGIAGYVATTGETLNIKDAYSHPLFYKEVDQKTGFKTRHILCFPIRSVSEQIIGVAQLCNKLNGNCFTKFDEERTLGFAIFVGLSLVQSLLYKKATDAKQRSKLANELMLYHMMVSQEEIDSYVKVAMPTKDSLHPDMDKFSFMPRISFAETDSIKVVLSMFNDLNVIKRWKVSESTLVRFILTVRRGYRDVPYHNWTHAWTVAHFSYTLLKKTNALDYLSDLEVFVLLVSCLCHDIDHRGTNNSFQISSQSVLASLYSSAGSVLERHHFAQAMCIVQTEHNNVFESLSSTDYKRALDLMQKMILATDLANHFKISKQLDELASTGIQKDEAAHRELLLSLFMTTSDLSDQTKPWESAVKVSDLLYQEFFSQGEMEKSLGYQPVKMMDKDLASIPDLQYSFLNNIAYPIYEKLSHFFPETNCILGNIKENQKQWSKI 619
            +D+Q+L+ +   ++  + +L VP  S   D V+AL C FNK+     FT  DE ++Q        ++ + L ++ +  ++ + ++LL+++K LF+HLDDVS+LL +I+ EARNL+NAE CS+FL+D N  EL+AKVFDG +  + S EIRIP   GIAG+VATTG+ LNI DAY+HPLFY+ VD  TGF+TR+ILCFPI++ ++++IGVA+L NK+NG  F+KFDE+    F+I+ G+S+  SLLYKK  +A+ RS LANE+M+YHM VS +E    +   +    ++  +   F++ PR S  E D+   +LSM  D+N I  +K+   TL RF L V++GYRD PYHNW HA++V+HF Y L K     +YL D+E+F L +SC+CHD+DHRGTNNSFQ++S+SVLA+LYSS GSV+ERHHFAQA+ I+ T   N+F+  S  DY+R LDLM+ +ILATDLA+H +I K L ++A  G  ++   H  LLL L MT+ DLSDQTK W++  K+++L+Y+EFFSQG++EK++G +P++MMD++ A IP+LQ SF+ +IA PIY+ L   FP+   +   +  N++ W+K+
Sbjct:  314 EDVQQLQSMLGCEL--QAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPR-SLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKV 898

The following BLAST results are available for this feature:

BLAST of TCONS_00066421-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00066421-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
PDE2A	0.000e+0	48.22	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=H...	[more]

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TCONS_00066421-protein (polypeptide) - C. hemisphaerica

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