TCONS_00065897-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00065897-protein
Unique NameTCONS_00065897-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length936

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00065897-protein ID=TCONS_00065897-protein|Name=TCONS_00065897-protein|organism=Clytia hemisphaerica|type=polypeptide|length=936bp
LRARFSEITPRAIQRACETLAPPDANTSNAVEVRRELDLRIGAAFTRFQT
LRFQRRFPNDLQEQLISYGSCQFPTLGFVVERYKQVQDFIPEDFYKIKVS
HSKEGCAVDFNWKRGRLYNERVCQMFCRMCQENPTATVIKVASKPKSKWR
PLPLDTVELEKTISRKLRINAKEVMKIAEKLYTNGIISYPRTETNIFPQG
MNLTPLVENQVADQQWGEFAQRVLNDGGPRPRQGKKTDNAHPPIHPIRHV
DNLQGNEKRVYEFIVRHFLACVSKDAQGKETTVEIDIANEKFSASGLYII
ARNYLDVYHYERWNSRMIPDYNEGETFQPDNIEMVQSETRPPPLLTEADL
IGLMEKYGIGTDATHAEHIETIKSRQYVGVQNDGTFLPGTLGMGLVEGYD
AMGFAMSKPYLRASLEEDLKRICEGQKNKDDVLAEQIRSYREVFIQAKEQ
VERLDEALSRYFGQPQQVPDEEENEPPMVEIIRKCPKCNSNDMITRKTKE
NSWMIGCSGYPNCRNSIFLPKFVLNIGKNERRCTKCRPEPVHFVNFEFKR
GSVPPTISTRYTGCVGCDEMLKEILNVNTFQRNTTQQANPQRNPATNQRQ
AGNAQANQRRAPNPPTNQRQGNQQNNRNTNNPRGGATNIRNPPPHGGNNQ
QYFGGDGFHGNRPNNQDGSDRNDGGAENEIVCNCDTNALKLTVRKEGPNQ
GRQFYKCANNPNKCDFFLWADEEAVAPNQGGGRGPGGGGGGANNYHGNNR
QRGNQEGQDGGEVMCQCNQLAPIRTVQKEGPNKGKQFYSCSKPRDQGCNF
FQWVDEESTNHNQGNHFNQQEDGGQVKCQCNQPAPIRTVQKEGPNKGKQF
YSCSKPRDQGCNFFQWVDEESTNQMNFQQRGGGRGGANFRGRGRGGYGNG
GGGGGGGGSGQQKGKKRKCGQCGQEGHNKKSCPFSR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_041292XLOC_041292Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00065897TCONS_00065897Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013497Topo_IA_cen
IPR003601Topo_IA_2
IPR003602Topo_IA_DNA-bd_dom
IPR010666Znf_GRF
IPR013498Topo_IA_Znf
IPR013825Topo_IA_cen_sub2
IPR023406Topo_IA_AS
IPR001878Znf_CCHC
IPR023405Topo_IA_core_domain
Vocabulary: Molecular Function
TermDefinition
GO:0003916DNA topoisomerase activity
GO:0003677DNA binding
GO:0008270zinc ion binding
GO:0003917DNA topoisomerase type I activity
GO:0003676nucleic acid binding
Vocabulary: Biological Process
TermDefinition
GO:0006265DNA topological change
Vocabulary: Cellular Component
TermDefinition
GO:0005694chromosome
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006265 DNA topological change
cellular_component GO:0005694 chromosome
molecular_function GO:0003677 DNA binding
molecular_function GO:0003916 DNA topoisomerase activity
molecular_function GO:0003917 DNA topoisomerase type I activity
molecular_function GO:0003676 nucleic acid binding
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 437..457
NoneNo IPR availableGENE3D3.40.50.140coord: 1..29
e-value: 0.0017
score: 18.2
NoneNo IPR availableGENE3D1.10.460.10coord: 330..456
e-value: 1.8E-26
score: 92.4
coord: 30..213
e-value: 1.9E-43
score: 147.7
NoneNo IPR availableGENE3D3.30.65.10coord: 463..529
e-value: 2.4E-12
score: 46.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 584..674
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 726..760
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 876..936
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 226..246
IPR013497DNA topoisomerase, type IA, centralPRINTSPR00417PRTPISMRASEIcoord: 184..193
score: 50.03
coord: 260..276
score: 35.01
coord: 358..372
score: 49.58
coord: 66..84
score: 38.5
IPR013497DNA topoisomerase, type IA, centralPFAMPF01131Topoisom_baccoord: 24..433
e-value: 1.3E-115
score: 386.6
IPR013497DNA topoisomerase, type IA, centralCDDcd00186TOP1Accoord: 26..444
e-value: 1.96306E-142
score: 430.873
IPR003601DNA topoisomerase, type IA, domain 2SMARTSM00436topIban2coord: 1..96
e-value: 9.9E-35
score: 131.4
IPR003602DNA topoisomerase, type IA, DNA-binding domainSMARTSM00437topIaneu2coord: 142..396
e-value: 3.4E-98
score: 342.2
IPR010666Zinc finger, GRF-typePFAMPF06839zf-GRFcoord: 763..806
e-value: 2.7E-19
score: 68.9
coord: 827..869
e-value: 2.2E-18
score: 66.0
coord: 681..722
e-value: 7.3E-16
score: 57.9
IPR013498DNA topoisomerase, type IA, zn fingerPFAMPF01396zf-C4_Topoisomcoord: 483..521
e-value: 2.4E-10
score: 39.9
IPR013825DNA topoisomerase, type IA, central region, subdomain 2GENE3D2.70.20.10coord: 226..329
e-value: 2.9E-26
score: 91.6
IPR023406DNA topoisomerase, type IA, active sitePROSITEPS00396TOPOISOMERASE_I_PROKcoord: 179..193
IPR001878Zinc finger, CCHC-typePROSITEPS50158ZF_CCHCcoord: 917..933
score: 9.488
IPR023405DNA topoisomerase, type IA, core domainSUPERFAMILY56712Prokaryotic type I DNA topoisomerasecoord: 2..447
coord: 483..492

Blast
[Close]
BLAST of TCONS_00065897-protein vs. Swiss-Prot (Human)
Match: TOP3A (DNA topoisomerase 3-alpha OS=Homo sapiens GN=TOP3A PE=1 SV=1)

HSP 1 Score: 865.529 bits (2235), Expect = 0.000e+0
Identity = 438/825 (53.09%), Postives = 554/825 (67.15%), Query Frame = 0 
Query:    1 LRARFSEITPRAIQRACETLAPPDANTSNAVEVRRELDLRIGAAFTRFQTLRFQRRFPNDLQEQLISYGSCQFPTLGFVVERYKQVQDFIPEDFYKIKVSHSKEGCAVDFNWKRGRLYNERVCQMFCRMCQENPTATVIKVASKPKSKWRPLPLDTVELEKTISRKLRINAKEVMKIAEKLYTNGIISYPRTETNIFPQGMNLTPLVENQVADQQWGEFAQRVLNDGGPRPRQGKKTDNAHPPIHPIRHVDNLQGNEKRVYEFIVRHFLACVSKDAQGKETTVEIDIANEKFSASGLYIIARNYLDVYHYERWNSRMIPDYNEGETFQPDNIEMVQSETRPPPLLTEADLIGLMEKYGIGTDATHAEHIETIKSRQYVGVQNDGTFLPGTLGMGLVEGYDAMGFAMSKPYLRASLEEDLKRICEGQKNKDDVLAEQIRSYREVFIQAKEQVERLDEALSRYFGQPQQVPDEEENEPPMVEIIRKCPKCNSNDMITRKTKENSWMIGCSGYPNCRNSIFLPKFVLNIGKNERRCTKCRPEPVHFVNFEFKRGSVPPTISTRYTGCV-GCDEMLKEILNVNTFQRNTTQQANPQRNPATNQRQAGNAQANQRRAPNPPTNQRQGNQQNNRNTNNPRGGATNIRNPPPHGGNNQQYFGGDGFHGNRPNNQDGSDRNDGGAENEIVCNCDTNALKLTVRKEGPNQGRQFYKCANNPNKCDFFLWADEEAVAPNQGGGRGPG----------GGGGGANNYHGNNRQRGNQEGQDGGEVMCQCNQLAPIRTVQKEGPNKGKQFYSCSKPRDQGCNFFQWVDEESTNHNQG 814
            LRARFSEITP A++ ACE L  PD   S+AV+VR+ELDLRIGAAFTRFQTLR QR FP  L EQLISYGSCQFPTLGFVVER+K +Q F+PE F++IKV+H  +   V+FNWKR RL+N   C +  ++C E+P ATV++V SKPKSKWRP  LDTVELEK  SRKLRINAKE M+IAEKLYT G ISYPRTETNIFP+ +NLT LVE Q  D +WG FAQ +L  GGP PR G K+D AHPPIHP ++ +NLQG+E+R+YEFIVRHFLAC S+DAQG+ETTVEIDIA E+F A GL I+ARNYLDVY Y+ W+ +++P Y +G  FQP  +EMV  ET PP LLTEADLI LMEK+GIGTDATHAEHIETIK+R YVG+  D  FLPG LGMGLVEGYD+MG+ MSKP LRA LE DLK IC+G+K+K  VL +Q++ Y++VFI+A  + ++LDEAL++YFG   ++  +E+  P M E IRKCP+CN  DM+ +  K   + + C G+P CR++++LP  VL   ++   C  C+P PV+ +  +FKRGS+PPT+   +  C+ GCD+ L+EIL++  F     + + P          +G  QANQ  + N   N +     ++R T + +  A  +  PPP                              G  N + CNC   A+ LTVRKEGPN+GRQF+KC  N   C+FFLWAD    +PN G G  P           G   G   + G     GN     G    C C+Q +  RTVQK+GPNKG+QF++C+KPR+Q C FFQWVDE +     G
Sbjct:  174 LRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQCN-KDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLR-FSGGPPRASQP----------SGRLQANQ--SLNRMDNSQHPQPADSRQTGSSKALAQTL--PPPTA---------------------------AGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKC--NGGSCNFFLWAD----SPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGF---GNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSG 946

HSP 2 Score: 116.701 bits (291), Expect = 1.700e-26
Identity = 71/202 (35.15%), Postives = 92/202 (45.54%), Query Frame = 0 
Query:  759 DGGEVMCQCNQLAPIRTVQKEGPNKGKQFYSCSKPRDQGCNFFQWVDEESTNHN-------------------QGNH---FNQQEDGGQ--VKCQCNQPAPIRTVQKEGPNKGKQFYSCSKPRDQGCNFFQWVDEESTNQMNFQQRGGGRGGANFRGRGRGGYGNGGGGGGGGGSGQQKGKKRKCGQCGQEGHNKKSCPFSR 936
            +   V C C Q A + TV+KEGPN+G+QF+ C+      CNFF W D  +                        G H   F    DG      C C+QP+  RTVQK+GPNKG+QF++C+KPR+Q C FFQWVDE +    +      G  G       R           G  +     K RKC  C Q GH +  CP +R
Sbjct:  807 ESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCN---GGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASSSDMGSTA----KKPRKCSLCHQPGHTRPFCPQNR 1001
The following BLAST results are available for this feature:
BLAST of TCONS_00065897-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TOP3A1.700e-2653.09DNA topoisomerase 3-alpha OS=Homo sapiens GN=TOP3A... [more]
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