TCONS_00065595-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00065595-protein
Unique Name	TCONS_00065595-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	804

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00065595-protein ID=TCONS_00065595-protein|Name=TCONS_00065595-protein|organism=Clytia hemisphaerica|type=polypeptide|length=804bp
FRVKVIMRLYLAIAPLVITTLVQLVSSQDVFNDFSVCGKTKDSRFLDQIS
RIVGGVNAAPGDLPWQAAMRSRNSGKPFCGATLISKKWAISAAHCQIRAG
QQIVLGAHNFRLGSEGSRQIRTVRRAINHQGYNDRTMTNDIALVELSQEV
EFNEFVKPACVLDSSKQLAAETPVVISGWGTTASGGSQPNILQEAEVKVV
SNQVCNSRYGNGIDQTMLCAAARGKDSCQGDSGGPLVVDLKDSNGGDRFF
LAGVVSFGIGCANPNYPGVYSNVASLRNWIQTNLASAGVQPATTNPGPNP
GTVAPLATTVVPPTTGSDAFNDFSVCGKTKNTRFLDSISRIVGGVNAAPG
DLPWQAAMRRTDSGKPFCGATLISKKWAISAAHCQIRAGQQIVLGAHNFR
LGAEASRQIRTVRRAINHQGYNDRTMTNDIALVELSQEVEFDEFVKPACV
LDSSKQLAAETPVVISGWGTTRSGGSQPNILQEAEVKVVSRQDCNSRYGN
GIDQTMLCAAARGKDSCQGDSGGPLVVDLKDLNGGDQFYLAGVVSFGIGC
ANPSYPGVYSNVASLRNWIQTNLASAGVYPATNNPEPSTTTTTTTKSTTT
TKKPVVTTTKKPVVTTTKKPVVTTTEVVTTEPPESTTTPEEPEVAVEEVQ
LIRYWSRKFRDHFYTTNFRDLGFMRKSYRFEGVQCKLAKNQVADSVPLYQ
YNKPDKDHMYTIDPKEIGVTTPGAEGKNGYKFQKIVGYCYPEPKDGTIPL
YRYYKAKIVNHFYTTDGKEMKTTTPGEFGQWNYLMQGITCYVYPGSYPLR
EYKS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041098	XLOC_041098	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00065595	TCONS_00065595	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001314	Peptidase_S1A
IPR001254	Trypsin_dom
IPR033116	TRYPSIN_SER
IPR018114	TRYPSIN_HIS
IPR009003	Peptidase_S1_PA

Vocabulary: **Molecular Function**
Term	Definition
GO:0004252	serine-type endopeptidase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
molecular_function	GO:0004252	serine-type endopeptidase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001314	Peptidase S1A, chymotrypsin family	PRINTS	PR00722	CHYMOTRYPSIN	coord: 225..237 score: 74.63 coord: 136..150 score: 37.59 coord: 80..95 score: 46.79
IPR001254	Serine proteases, trypsin domain	SMART	SM00020	trypsin_2	coord: 340..569 e-value: 1.7E-90 score: 316.6 coord: 51..280 e-value: 5.3E-93 score: 325.0
IPR001254	Serine proteases, trypsin domain	PFAM	PF00089	Trypsin	coord: 52..280 e-value: 2.5E-67 score: 226.8 coord: 341..569 e-value: 5.2E-66 score: 222.5
IPR001254	Serine proteases, trypsin domain	PROSITE	PS50240	TRYPSIN_DOM	coord: 341..574 score: 35.039
IPR001254	Serine proteases, trypsin domain	PROSITE	PS50240	TRYPSIN_DOM	coord: 52..285 score: 35.332
IPR001254	Serine proteases, trypsin domain	CDD	cd00190	Tryp_SPc	coord: 341..572 e-value: 1.35511E-87 score: 278.006
IPR001254	Serine proteases, trypsin domain	CDD	cd00190	Tryp_SPc	coord: 52..283 e-value: 7.57255E-90 score: 283.784
None	No IPR available	GENE3D	2.40.10.10		coord: 340..351 e-value: 1.1E-4 score: 21.3 coord: 51..62 e-value: 1.1E-4 score: 21.3
None	No IPR available	GENE3D	2.40.10.10		coord: 157..287 e-value: 2.4E-44 score: 150.4 coord: 446..576 e-value: 1.1E-43 score: 148.2
None	No IPR available	GENE3D	2.40.10.10		coord: 352..373 e-value: 1.0E-14 score: 53.9 coord: 63..83 e-value: 6.7E-15 score: 54.5
None	No IPR available	GENE3D	2.40.10.10		coord: 374..445 e-value: 4.9E-23 score: 80.5 coord: 84..156 e-value: 1.3E-23 score: 82.4
None	No IPR available	PIRSF	PIRSF001155	C1r_C1s_MASP	coord: 27..287 e-value: 7.4E-54 score: 180.9 coord: 307..576 e-value: 3.2E-53 score: 178.8
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 579..598
IPR033116	Serine proteases, trypsin family, serine active site	PROSITE	PS00135	TRYPSIN_SER	coord: 226..237
IPR033116	Serine proteases, trypsin family, serine active site	PROSITE	PS00135	TRYPSIN_SER	coord: 515..526
IPR018114	Serine proteases, trypsin family, histidine active site	PROSITE	PS00134	TRYPSIN_HIS	coord: 90..95
IPR018114	Serine proteases, trypsin family, histidine active site	PROSITE	PS00134	TRYPSIN_HIS	coord: 379..384
IPR009003	Peptidase S1, PA clan	SUPERFAMILY	50494	Trypsin-like serine proteases	coord: 312..573
IPR009003	Peptidase S1, PA clan	SUPERFAMILY	50494	Trypsin-like serine proteases	coord: 6..284

Blast

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BLAST of TCONS_00065595-protein vs. Swiss-Prot (Human)
Match: TMPS9 (Transmembrane protease serine 9 OS=Homo sapiens GN=TMPRSS9 PE=1 SV=2)

HSP 1 Score: 327.405 bits (838), Expect = 9.525e-98
Identity = 221/650 (34.00%), Postives = 335/650 (51.54%), Query Frame = 0

Query:   51 RIVGGVNAAPGDLPWQAAMRSRNSGKPFCGATLISKKWAISAAHC----QIRAGQQIVLGAHNFRLGSEGSRQIRTVRRAINHQGYNDRTMTNDIALVELSQEVEFNEFVKPACVLDSSKQLAAETPVVISGWGTTASGG-SQPNILQEAEVKVVSNQVCNSRYGNGIDQTMLCAA-ARGK-DSCQGDSGGPLVVDLKDSNGGDRFFLAGVVSFGIGCANPNYPGVYSNVASLRNWI-----QTNLASAGVQPATTNPGPNPGTVAPLATTVVPPTTGSDAFNDFSV----------CGKTKNTRFLDSISRIVGGVNAAPGDLPWQAAMRRTDSGKPFCGATLISKKWAISAAHC-------QIRAGQQIVLGAHNFRLGAEASRQIRTVRRAINHQGYNDRTMTNDIALVELSQEVEFDEFVKPACVLDSSKQLAAETPVVISGWGTTRSG-GSQPNILQEAEVKVVSRQDCNSRYGNGIDQTMLCAA-ARGK-DSCQGDSGGPLVVDLKDLNGGDQFYLAGVVSFGIGCANPSYPGVYSNVASLRNWIQTNLASAGVYPATNNPEPSTTTTTTTKSTTTTKKPVV--TTTKKP----VVTTTKKPVVTTTEVVTT---------EPPESTTTPEEPEVAVEEVQLIR 653
            RIVGG+ A+PG+ PWQA++R     + FCGA +I+ +W +SAAHC    Q        +GA  +  GSE S     V + + H  YN  T   D+A++EL+  + F   ++P C+  ++         +ISGWG        +P +LQ+A V+++   +C S YG+ +   M+CA    GK DSCQGDSGGPLV +  + +G  RFFLAG+VS+GIGCA    PGVY+ V  LR+WI     + ++  A                +P +  V  PT    A +   +          CG       ++  +R+VGG  AA G++PWQ +++  +  + FCGAT++  +W +SAAHC       Q+RA     LG  +  LG   S     +RR + H  YN   +  D+A++EL+  + F+++++P C+  + ++       +ISGWG T+ G  ++P +LQ+A V ++ ++ C+  Y   +   M+CA    GK DSCQGDSGGPL  +         FYLAG+VS+GIGCA    PGVY+ +  L+ WI   ++S    P   +P PSTT    T S  TT    V   T  +P        T +P  +T   V+T         + PE+TT  + P+  +    L R
Sbjct:  202 RIVGGMEASPGEFPWQASLRENK--EHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGA-TYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCE--EPSG--RFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPA---MEKPTRVVGGFGAASGEVPWQVSLK--EGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAH----LGTASL-LGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACE----EAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQ---PLPMSP-PSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTR 826

HSP 2 Score: 312.768 bits (800), Expect = 1.849e-92
Identity = 206/583 (35.33%), Postives = 302/583 (51.80%), Query Frame = 0

Query:   46 LDQISRIVGGVNAAPGDLPWQAAMRSRNSGKPFCGATLISKKWAISAAHC-------QIRAGQQIVLGAHNFRLGSEGSRQIRTVRRAINHQGYNDRTMTNDIALVELSQEVEFNEFVKPACVLDSSKQLAAETPVVISGWGTTASG-GSQPNILQEAEVKVVSNQVCNSRYGNGIDQTMLCAA-ARGK-DSCQGDSGGPLVVDLKDSNGGDRFFLAGVVSFGIGCANPNYPGVYSNVASLRNWIQTNLASAGVQP------------ATTNPGPNPGTVAPLATTVVPP------TTGSDAFNDFSVCGKTK--NTRFLDS------------------ISRIVGGVNAAPGDLPWQAAM--RRTDSGKPFCGATLISKKWAISAAHCQIRAG---QQIVLGAHNFRLGAEASRQIRTVRRAINHQGYNDRTMTNDIALVELSQEVEFDEFVKPACVLDSSKQLAAETPVVISGWGTTRSGGSQPNILQEAEVKVVSRQDCNSRYGNGIDQTMLCAA--ARGKDSCQGDSGGPLVVDLKDLNGGDQFYLAGVVSFGIGCANPSYPGVYSNVASLRNWIQTNL 573
            +++ +R+VGG  AA G++PWQ +++     + FCGAT++  +W +SAAHC       Q+RA     LG  +  LG  GS     +RR + H  YN   +  D+A++EL+  + FN++++P C+  + ++       +ISGWG T  G  ++P +LQ+A V ++  + C+  Y   +   M+CA    GK DSCQGDSGGPL  +         F+LAG+VS+GIGCA    PGVY+ +  L+ WI   ++S   QP            ATT+P    G   P AT   P        TG  A +  S    T    T F D+                  ++RIVGG  A  G+ PWQ ++  RR +     CGA L++++W +SAAHC    G   Q        F  GAE   Q+  V R   H  YN  T+  D+AL+EL+  V     V+P C+ + + +    T  VI+GWG+ R GGS    LQ+A V+++S Q C   Y   I   MLCA     G DSC GD+GGPL    ++ +G  ++ L GV S+G GC  P +PGVY+ VA++R WI  ++
Sbjct:  498 MEKPTRVVGGFGAASGEVPWQVSLK--EGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAH----LGTASL-LGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACE----EAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS---QPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREH---RCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEG--QLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLAC--REPSG--RWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057

The following BLAST results are available for this feature:

BLAST of TCONS_00065595-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00065595-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
TMPS9	9.525e-98	34.00	Transmembrane protease serine 9 OS=Homo sapiens GN...	[more]

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TCONS_00065595-protein (polypeptide) - C. hemisphaerica