Wnt receptor frizzled 2 (polypeptide) - C. hemisphaerica

Overview


Name	Wnt receptor frizzled 2
Unique Name	TCONS_00063634-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	579

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00063634-protein ID=TCONS_00063634-protein|Name=Wnt receptor frizzled 2|organism=Clytia hemisphaerica|type=polypeptide|length=579bp
MNTNSVSQVTILLLLCCGTLVDSLGRGRTRPKAKKCEKITIPLCKDVGYN
ETYMPNNFGQSSQFEAGLIIHQFWPLVLINCSPLLKHFVCSLYAPMCDPI
YFKEIVPCRSFCEDVRDSCTAIMKNNGFDWPSHLKCEQFPTRKENSICMK
PSNAHVSKNNKTTNKPTSSPNSKTVKPNTNNHGTSGGGTKQSDGPYRPPT
HINTNGGARGCGCMCKAPFVYPNASSRGELPPCVLPCKQFYFKEDEANFV
TFWLGLWSIIAFIGTLITIATFFIDRSRFTQAERPIVFMSFCYFLVAFGY
IVRLIYGHDAIACDSKTGLARYAATGPAHCTTVFFMTYFFANVAWIWWVV
LSMNWFLSSGLRWPSKAISSYSQYFHFIAWIVPTVQTMAILAMSAIDGDP
VSGLCSVGNHNNNNLTIFMIAPLLIYTMLSLSFFVAGVIAIVQRKRHNKS
NNGQITPEYFDEERQACSYVSKIGVYTFMVFFPAFTLIGCYFYEHNNKEI
WEKSTNCPCVRDKVRPNYYVYLLKYFMSLVIGLISGFWVLDSRTVDSWKR
FLLKFVKDDCNENNNLLAAQKYNGAPVQL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_039886	XLOC_039886	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00063634	TCONS_00063634	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000539	Frizzled
IPR020067	Frizzled_dom
IPR017981	GPCR_2-like

Vocabulary: **Biological Process**
Term	Definition
GO:0007166	cell surface receptor signaling pathway

Vocabulary: **Cellular Component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding
GO:0004888	transmembrane signaling receptor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007166	cell surface receptor signaling pathway
cellular_component	GO:0016021	integral component of membrane
cellular_component	GO:0016020	membrane
molecular_function	GO:0005515	protein binding
molecular_function	GO:0004888	transmembrane signaling receptor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000539	Frizzled protein	PRINTS	PR00489	FRIZZLED	coord: 520..540 score: 42.67 coord: 420..442 score: 30.96 coord: 281..303 score: 41.74 coord: 332..356 score: 44.16 coord: 253..275 score: 40.17 coord: 375..398 score: 48.5
IPR000539	Frizzled protein	SMART	SM01330	Frizzled_2	coord: 240..558 e-value: 3.1E-126 score: 435.4
IPR000539	Frizzled protein	PFAM	PF01534	Frizzled	coord: 241..553 e-value: 3.9E-100 score: 335.0
IPR020067	Frizzled domain	SMART	SM00063	FRI_4	coord: 35..153 e-value: 5.9E-45 score: 165.4
IPR020067	Frizzled domain	GENE3D	1.10.2000.10		coord: 27..155 e-value: 7.0E-36 score: 122.8
IPR020067	Frizzled domain	PFAM	PF01392	Fz	coord: 36..143 e-value: 8.9E-30 score: 103.5
IPR020067	Frizzled domain	PROSITE	PS50038	FZ	coord: 31..151 score: 24.95
IPR020067	Frizzled domain	SUPERFAMILY	63501	Frizzled cysteine-rich domain	coord: 35..152
None	No IPR available	GENE3D	1.20.1070.10		coord: 237..541 e-value: 1.4E-20 score: 72.9
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 150..201
IPR017981	GPCR, family 2-like	PROSITE	PS50261	G_PROTEIN_RECEP_F2_4	coord: 250..547 score: 30.425

Blast

[Close]

BLAST of Wnt receptor frizzled 2 vs. Swiss-Prot (Human)
Match: FZD5 (Frizzled-5 OS=Homo sapiens GN=FZD5 PE=1 SV=2)

HSP 1 Score: 454.521 bits (1168), Expect = 3.691e-154
Identity = 219/543 (40.33%), Postives = 323/543 (59.48%), Query Frame = 0

Query:   24 LGRGRTRPKAKKCEKITIPLCKDVGYNETYMPNNFGQSSQFEAGLIIHQFWPLVLINCSPLLKHFVCSLYAPMCDPIYFKEIVPCRSFCEDVRDSCTAIMKNNGFDWPSHLKCEQFPT--RKENSICMKPSNAHVSKNNKTTNKPTSSPNSKTVKPNTNNHGTSGGGTKQSDGPYRPPTHINTNGGARGCGCMCKAPFV------YP--NASSRGELPPCVLPCKQFYFKEDEANFVTFWLGLWSIIAFIGTLITIATFFIDRSRFTQAERPIVFMSFCYFLVAFGYIVRLIYGHDAIACDSKTGLARYAATGPAHCTTVFFMTYFFANVAWIWWVVLSMNWFLSSGLRWPSKAISSYSQYFHFIAWIVPTVQTMAILAMSAIDGDPVSGLCSVGNHNNNNLTIFMIAPLLIYTMLSLSFFVAGVIAIVQRKRHNKSNNGQITPEYFDEERQACSYVSKIGVYTFMVFFPAFTLIGCYFYEHNNKEIWEKSTNCPCV-----RDKVRPNYYVYLLKYFMSLVIGLISGFWVLDSRTVDSWKRF 551
            +GR     KA  C++IT+P+C+ +GYN T+MPN F   +Q EAGL +HQFWPLV I CSP L+ F+CS+Y P+C P Y K + PCRS CE  +  C+ +M+  GF WP  + C++ P   R    +CM       +++  TT  P   P   T+ P       SGG    + GP+                C C+ PFV      +P  N    G++P C +PC Q  F  DE  F TFW+GLWS++ FI T  T+ATF ID  RF   ERPI+F+S CY  V+ G++VRL+ GH ++AC  +     Y  TGPA CT VF + YFF   + IWWV+LS+ WFL++G++W ++AI+ Y+QYFH  AW++P+V+++  LA+S++DGDPV+G+C VGN N N+L  F++ PL++Y ++   F +AG +++  R R      G  T    D+  +    + +IG++T +   PA  ++ CY YE + +E WE +  C C      + + +P Y+V +LKYFM LV+G+ SG W+   +TV+SW+RF
Sbjct:   21 VGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMD-----YNRSEATTAPPRPFPAKPTL-PGPPGAPASGGECP-AGGPFV---------------CKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLF-RIRSVIKQGGTKT----DKLEK---LMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRF 533

The following BLAST results are available for this feature:

BLAST of Wnt receptor frizzled 2 vs. Swiss-Prot (Human)

BLAST of Wnt receptor frizzled 2 vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
FZD5	3.691e-154	40.33	Frizzled-5 OS=Homo sapiens GN=FZD5 PE=1 SV=2	[more]

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Wnt receptor frizzled 2 (polypeptide) - C. hemisphaerica