TCONS_00063205-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063205-protein
Unique NameTCONS_00063205-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length461

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063205-protein ID=TCONS_00063205-protein|Name=TCONS_00063205-protein|organism=Clytia hemisphaerica|type=polypeptide|length=461bp
MSSIAGNSARKFEPGTECVAKYDFKGNSQADLPFRKGDLIEIKRATQDPN
WYDARRVSDGKTGIIPINYVQQRRGLHIHEMPWFFGKISRDEAEKLLKPR
TVGLFLVRESTNYPGDYTLCVVSPSSQMKVEHYRITSKDNNKYSVDDETY
FSTLSELVKHYKKDADGLCTTLVKSLKKEDNAISSTAFKESFQKEGWSVA
TEDITFKEKIGTGEFGEVFKGDYQGRAVAIKQLKDDTHAAQSFLREASVM
TTLQHQNLVVLIGISFRGQDILILTEHCSKGSLVNYLRSRGRAVIKQEEQ
LSFARDVCTGMEYLEEKHMIHRDLAARNVLLTDNPGSSCLLAKVSDFGLA
KDQQIQQKDAEKFPVKWTAPEAIREKKFSSKSDVWSFGILLWEIFSFGRN
PYPRVSLDNVLDKVLSGYRMEKPDACPPHIYQIMLKCWCTEPDKRPSFRE
MSPKLYRETNL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_039599XLOC_039599Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063205TCONS_00063205Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR000980SH2
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001452SH3 domainPRINTSPR00452SH3DOMAINcoord: 61..73
score: 41.45
coord: 16..26
score: 34.24
coord: 30..45
score: 31.3
IPR001452SH3 domainSMARTSM00326SH3_2coord: 16..74
e-value: 4.5E-16
score: 69.4
IPR001452SH3 domainPFAMPF00018SH3_1coord: 19..66
e-value: 2.6E-11
score: 42.8
IPR001452SH3 domainPROSITEPS50002SH3coord: 13..75
score: 15.922
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 17..99
IPR000980SH2 domainPRINTSPR00401SH2DOMAINcoord: 102..112
score: 57.86
coord: 129..139
score: 42.7
coord: 83..97
score: 56.95
coord: 114..125
score: 34.36
coord: 150..164
score: 43.83
IPR000980SH2 domainSMARTSM00252SH2_5coord: 81..167
e-value: 1.8E-32
score: 123.9
IPR000980SH2 domainPFAMPF00017SH2coord: 83..161
e-value: 1.6E-24
score: 85.7
IPR000980SH2 domainGENE3D3.30.505.10coord: 84..178
e-value: 2.8E-34
score: 116.7
IPR000980SH2 domainPROSITEPS50001SH2coord: 83..176
score: 24.908
IPR000980SH2 domainSUPERFAMILY55550SH2 domaincoord: 78..222
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 382..404
score: 64.74
coord: 426..448
score: 44.67
coord: 313..331
score: 62.49
coord: 275..288
score: 44.82
coord: 363..373
score: 68.35
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 204..455
e-value: 2.5E-88
score: 295.6
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 204..455
e-value: 2.3E-121
score: 419.2
NoneNo IPR availableGENE3D1.10.510.10coord: 282..457
e-value: 3.4E-46
score: 156.3
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 292..459
e-value: 5.3E-56
score: 188.3
coord: 193..300
e-value: 7.4E-10
score: 35.5
NoneNo IPR availableGENE3D3.30.200.20coord: 184..281
e-value: 1.2E-23
score: 82.5
NoneNo IPR availableGENE3D2.30.30.40coord: 7..83
e-value: 2.9E-20
score: 71.2
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 210..231
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 319..331
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 204..455
score: 41.121
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 184..451

Blast
BLAST of TCONS_00063205-protein vs. Swiss-Prot (Human)
Match: CSK (Tyrosine-protein kinase CSK OS=Homo sapiens GN=CSK PE=1 SV=1)

HSP 1 Score: 475.707 bits (1223), Expect = 2.970e-166
Identity = 238/446 (53.36%), Postives = 313/446 (70.18%), Query Frame = 0
Query:   15 GTECVAKYDFKGNSQADLPFRKGDLIEIKRATQDPNWYDARRVSDGKTGIIPINYVQQRRGLH----IHEMPWFFGKISRDEAEKLLKPRTVGLFLVRESTNYPGDYTLCVVSPSSQMKVEHYRITSKDNNKYSVDDETYFSTLSELVKHYKKDADGLCTTLVKSLKKEDNAISSTAFKESFQKEGWSVATEDITFKEKIGTGEFGEVFKGDYQGRAVAIKQLKDDTHAAQSFLREASVMTTLQHQNLVVLIGISFRGQD-ILILTEHCSKGSLVNYLRSRGRAVIKQEEQLSFARDVCTGMEYLEEKHMIHRDLAARNVLLTDNPGSSCLLAKVSDFGLAKDQQIQQKDAEKFPVKWTAPEAIREKKFSSKSDVWSFGILLWEIFSFGRNPYPRVSLDNVLDKVLSGYRMEKPDACPPHIYQIMLKCWCTEPDKRPSFREMSPKL 455
            GTEC+AKY+F G ++ DLPF KGD++ I   T+DPNWY A+    G+ GIIP NYVQ+R G+     +  MPWF GKI+R++AE+LL P   GLFLVRESTNYPGDYTLCV   S   KVEHYRI     +K S+D+E YF  L +LV+HY  DADGLCT L+K    E     + A ++ F + GW++  +++   + IG GEFG+V  GDY+G  VA+K +K+D   AQ+FL EASVMT L+H NLV L+G+    +  + I+TE+ +KGSLV+YLRSRGR+V+  +  L F+ DVC  MEYLE  + +HRDLAARNVL++++      +AKVSDFGL K+    Q D  K PVKWTAPEA+REKKFS+KSDVWSFGILLWEI+SFGR PYPR+ L +V+ +V  GY+M+ PD CPP +Y++M  CW  +   RPSF ++  +L
Sbjct:   11 GTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKN-KVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV---SCDGKVEHYRIMYH-ASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVME----GTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDA-TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDN-----VAKVSDFGLTKEASSTQ-DTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440          
The following BLAST results are available for this feature:
BLAST of TCONS_00063205-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CSK2.970e-16653.36Tyrosine-protein kinase CSK OS=Homo sapiens GN=CSK... [more]
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