TCONS_00061810-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00061810-protein
Unique Name	TCONS_00061810-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	742

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00061810-protein ID=TCONS_00061810-protein|Name=TCONS_00061810-protein|organism=Clytia hemisphaerica|type=polypeptide|length=742bp
MSEPSSDYDSYSMQQSKNLSSSRTSLDSLGMTLEGDDTDYNAYNHFNDSE
YDSDLDAEDVPETWSELVDKKVQRKMHAKDIKRQDVIYELIQTEAQYVRT
LNVMKKIYMNALVSLNFDDRTIHTIFPELEELIDLNGGFLKAMKQRQEES
QNYCIESIGDILLEFFGGEKGERLKYAYGTFCSKHLEAVAKYKEIMKLDK
NNVSKVMKKCLLMERSRRLTLPECITYVTIRMTKYPLLIEAIIKATKESK
PDYEMLKTSLSLVKEVLVAVDDAVNDYEQQKELNNLRKNLDHKNVVEIKT
GQTKTIYRAKNVFRSRSKLKCDKKTQLRGKSKLYETRMIVLADKIIFFQD
NSGGKLQLLQVDNKAPELPLRNLMVRDVATDKQAIFLVSTSKDAAQIYEI
VCENSKDQRQFMAKLKAYIKDCPEEDEETDNEEEAKREEEERMQKLKEMI
ENLQSADEKMLRTFTDKNRLVAEMRDLIECMDDSSIIKASSPMELKTNDI
VSGREILEQCIIEVNQLSTTVSSPTDGPIQSPSPSPLTSGSNTIGASASR
SQTVPNFTNINRSVSQRPALGRPSLNFTETDSAAVKRKPSQTTLLNVWKS
KAMGSQEDLASISSHSTSMTSLTSTVSQMQICQTLQDRLDGLRDITTKQD
TEVAKMRLELQESRNEIAKLRNEKKELEDRLVTQQKETDRSLRNEREQYY
KLSREFKRTTDKMNRSLEEKKQQYQHLLETYSNRSNPEEVYL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_038777	XLOC_038777	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00061810	TCONS_00061810	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000219	DH-domain
IPR011993	PH_dom-like

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005089	Rho guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 710..734
None	No IPR available	COILS	Coil	Coil	coord: 653..694
None	No IPR available	COILS	Coil	Coil	coord: 429..463
None	No IPR available	GENE3D	1.20.1170.10		coord: 513..738 e-value: 8.1E-4 score: 17.9
None	No IPR available	GENE3D	1.20.900.10		coord: 59..292 e-value: 8.5E-52 score: 175.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..32
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 520..589
None	No IPR available	CDD	cd00160	RhoGEF	coord: 83..271 e-value: 2.72225E-34 score: 128.57
IPR000219	Dbl homology (DH) domain	SMART	SM00325	RhoGEF_3	coord: 86..272 e-value: 5.0E-45 score: 165.6
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 86..269 e-value: 4.9E-34 score: 118.1
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 82..273 score: 28.775
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 62..293
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 310..460 e-value: 1.2E-8 score: 33.9
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 326..421

Blast

[Close]

BLAST of TCONS_00061810-protein vs. Swiss-Prot (Human)
Match: ARHGI (Rho guanine nucleotide exchange factor 18 OS=Homo sapiens GN=ARHGEF18 PE=1 SV=3)

HSP 1 Score: 252.292 bits (643), Expect = 4.989e-71
Identity = 226/775 (29.16%), Postives = 374/775 (48.26%), Query Frame = 0

Query:   16 SKNLSSSRTSLDSLGMTLEGDDTDY--NAYNHFNDSEYDSDLDAEDVPETWSELVDKKVQRKMHAKDIKRQDVIYELIQTEAQYVRTLNVMKKIYMNALVS-LNFDDRTIHTIFPELEELIDLNGGFLKAMKQRQEES------QNYCIESIGDILLEFFGGEKGERLKYAYGTFCSKHLEAVAKYKEIMKLDKNNVSKVMKKCLLMERSRRLTLPECITYVTIRMTKYPLLIEAIIKATKESKPDYEMLKTSLSLVKEVLVAVDDAVNDYEQQKELNNLRKNLDHKNVVEIKTGQTKTIYRAKNVFRSRSKLK---CDKKTQLRGKSKLYETRMIVLADKIIFFQDNSGGKLQLLQVDNKAPELPLRNLMVRDVATDKQAIFLVSTSKDAAQIYEIVCENSKDQRQFMAKLKAYIKDCPEEDEETDN-EEEAKREEEERMQKLKEMIENLQSADEKMLRTFTDKNRL---VAEMRDLIECMDDSSIIKASSPMELKTNDIVSGREILEQCIIEV--------NQLSTTVSSPTDGPIQSPSPSPLTSGSNTIGASASRSQTVPNFTNINRSVSQRPALGRPSLNFTETDSAAVK-RKPSQTTLLNVWKSKAMGSQEDLAS-ISSHSTSMTSLTSTVSQ---MQICQTLQDRLDGLRDITTKQDTEVAKMRLELQESRNEI-------------AKLRNEKKELEDRLVTQQ------KETDRSLRNEREQYYKLSREFKRTTDKMNRS-------------LEEKKQQYQHLLE 729
            S  L   +T+ DSL +T    ++ +  + Y     SE +SD   E   E+WS  VD    +K   + +KRQDV+YEL+QTE  +VRTL +M K+Y  AL   L F  + I  +FP  ++L++ +  FL  +K+R++ES      +NY I+ IGD+L++ F GE GER+K  YG FCS H EAV+ YK +++ +K     ++KK       RRL + ECI  VT R+TKYP+L+E II+ T+    DYE L  +L+L+K+++  VD  V++ E+ + L  +   +D K+  ++K G T   +R +++ + +  L+   C K T  R K  L     I+L D ++  Q+    K     VD+K P + L+ L+VR+VA +++A+FL+S S    ++YEI   + +D+  +MA ++  ++ CP+E+E   +  EE ++  E R  +L++  E L   D+ + ++  +K ++   +AEM  L +      + +   P E      + G  IL+  + E+         QL +      DG            GS+T      R++T   +   N         G      + TD      R P  +  L +  S   GS E+    + +  T       TV +   +Q  QTL   L  L+ +   QD+ V   R  +QE   +               + RN +K+ E+R   ++       E  R  R  + Q+ +L R   R  ++   +             LE ++Q YQH LE
Sbjct:  192 SAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESD-GHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKK-FQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMDLKSSSKLKNGLT---FRKEDMLQRQLHLEGMLCWKTTSGRLKDIL----AILLTDVLLLLQEKD-QKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAHIQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLEMAEMGGLEDLPQPRGLFRGGDPSE-----TLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDG------------GSST--GPPRRAETFAGYDCTNSPTKN----GSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPGSSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLE 933

The following BLAST results are available for this feature:

BLAST of TCONS_00061810-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00061810-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ARHGI	4.989e-71	29.16	Rho guanine nucleotide exchange factor 18 OS=Homo ...	[more]

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TCONS_00061810-protein (polypeptide) - C. hemisphaerica