Breast cancer anti estrogen resistance protein (polypeptide) - C. hemisphaerica

Overview
NameBreast cancer anti estrogen resistance protein
Unique NameTCONS_00055210-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1372

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00055210-protein ID=TCONS_00055210-protein|Name=Breast cancer anti estrogen resistance protein|organism=Clytia hemisphaerica|type=polypeptide|length=1372bp
MGWHTLKRQKSAQKAALAAKEQQAHQQKVSTPKTERNGSLKLGSIRSSFK
EKNIKNLSIQPPPSPVRHDQPFSSLNDKVQTLLARAAYDNHADAPDELNI
RKGDIVTVIEKDIDGLTGWWLCLLHGEQGIVPGNRLQVIDPMQLDQLERK
SASTKKRASYETDDNSDGHDALDGGAPNNYDYLPNPVKTPGFVPQLSIKD
MFDIPLKGKSGKEQVEISQEVYDIPSSLNSTLDTTQEIYDIPSNRSSNRS
SGNLNQSNSIPTGYDSPRTGRKEYDAGPTETYDVPSNLNQRSARKQHEGP
TETYDVPSQLNRSRVEEPSETYDVPSNLNKRVSPKHIDGPTETYDVPSNL
RKQAPPKQPEPYRVPNNIPAVSDEVYDVPKSRTSIDVDELMGEIMDSPFN
EDPISSTIKRTPLNSNTSTPRGSFTSSNTGIDAADGPSQEIYDVPKKDVN
GGRPPNTGRKNFHLQSPASNTMSHTLPRGFSPRSNNAKNLKNTPTRLQEI
YNVPSSSVAATANAPLNRSTPGTPQSARKSKESYPTSQEIYDVPAPRNQD
PTTNPEFIDMLKQLERTDNATSSNRSSFNSTHSSSKRASQELYDVPTSNP
TSSRRSDPTAVSQYQNTQSEYRNTGIQQEIYDVPPSSHRSQEELYDVPPP
RNTQTLGRSTKINRLSGGNDLNFIPPAQTSTPRGQEIYDTPQSSSRRRSP
APEQYKIPSYNKASRNDGPSEIYDVPTNNKNSSQQEIYDVPSAHDVDRVM
ADAYGSHKTTRNHNNNLLTPQLPVDDDDYVDYHDIWSKQPPKELMRQHAK
SISGRPNSRPPSGGGSPLSFAQKRLSTGSTESGGKKSVLDQINFEAVKEL
QLTVSEAVERLGKLHLAVDTCVQTLKMFQDENWLEISSLNSHIHSIRDFS
GKLKTALRLLTEFGLGTLVNTTNNINGEALMDKIIDDVEPLLESYYKVKI
CLMHLDSNNWAVPASRNSTTDKFFATLNAIMILAQRIPDQCRSFTLAVKN
NASELFTPDPVEDLTKHVKEMDIKRQQQPQQKIQLLTEPTMSAEALRKEL
AGRRQQARDSTLRPVPRIPPKPTLPHQRRSLAGSMDPPDNPRYSLANRAG
YGHIERLVTEYQPENSKQKKYASDPTTPSHTTSESKMWGGSCPVLLDRNS
AAAATPLHNAESMSSSSSVGASIPEETIEIKKTDIGTNKNFPSDSNLISP
VLTPLHTRSASLPWDDKLKNVFSFEDNGPKSPNAISPLDHRDIESLEFFC
RQVESQVLLLRESMKNLTEAVENQEEPVVFVSHSKFIILTAHKVVHSGQE
ISERLIHTDIKSKIKEHTTHLTVCIRGVVSATKTAALEYPETTALMEMIS
SVLALGDAVRIIHRECRQALNA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034770XLOC_034770Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00055210TCONS_00055210Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR021901CAS_DUF3513
IPR014928Serine_rich
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1250..1270
NoneNo IPR availableGENE3D2.30.30.40coord: 9..325
e-value: 1.0E-16
score: 60.8
NoneNo IPR availableGENE3D1.20.1420.10coord: 1028..1368
e-value: 8.5E-6
score: 25.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 568..735
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..44
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 790..835
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1048..1091
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1112..1140
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 149..186
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 511..555
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 241..368
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 398..491
NoneNo IPR availableCDDcd11564FAT-like_CAS_Ccoord: 1242..1367
e-value: 9.37636E-43
score: 152.772
NoneNo IPR availableCDDcd11844SH3_CAScoord: 83..138
e-value: 8.84572E-27
score: 104.735
IPR001452SH3 domainSMARTSM00326SH3_2coord: 82..140
e-value: 8.5E-15
score: 65.2
IPR001452SH3 domainPFAMPF00018SH3_1coord: 85..132
e-value: 3.1E-10
score: 39.4
IPR001452SH3 domainPROSITEPS50002SH3coord: 79..141
score: 14.072
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 80..152
IPR021901CAS family, DUF3513PFAMPF12026DUF3513coord: 1231..1356
e-value: 4.4E-27
score: 95.4
IPR014928Serine rich protein interactionPFAMPF08824Serine_richcoord: 853..1007
e-value: 3.0E-21
score: 76.0

Blast
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BLAST of Breast cancer anti estrogen resistance protein vs. Swiss-Prot (Human)
Match: BCAR1 (Breast cancer anti-estrogen resistance protein 1 OS=Homo sapiens GN=BCAR1 PE=1 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 4.365e-26
Identity = 110/355 (30.99%), Postives = 149/355 (41.97%), Query Frame = 0 
Query:   82 LLARAAYDNHADAPDELNIRKGDIVTVIEKDIDGLTGWWLCLLHGEQGIVPGNRLQVIDPMQLDQLERKSASTKKRASYETDDNSDGHDALDGGA-------PNNYD------YL-PNPVK-------TPGFVPQLS----------------------IKDMFDIPLKGKSGKEQVEISQEVYDIPSSLNSTLDTTQEIYDIPSNRSSNRSSGNLNQSN-SIPTGYDSPRTGRKE-YDAGPTET--YDVPSNLNQRSARKQHEGPTETYDVPSQLNRSRVEEPSETYDVPSNLNKRVSPKHIDGPTETYDVPSNLRKQAPPKQPEP-YRVPNNI-------PAVSDEVYDVPKS 381
            +LA+A YDN A++PDEL+ RKGDI+TV+E+D  GL GWWLC LHG QGIVPGNRL+++    +   ++K A               G  A    A       PN Y       YL P P K        PG  PQ                          D++ +P  G  G      +Q++Y +P S     D    IY +P +  +    G    +   +PT     R G+   Y+A   E   YD+P +L          GP + YDVP        +   E YD P    K   P   D   E YDVP ++ K  PP      Y VP ++       P + +E YDVP +
Sbjct:    6 VLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKIL----VGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVP-PGPGGP-----AQDIYQVPPSAGMGHD----IYQVPPSMDTRSWEGTKPPAKVVVPT-----RVGQGYVYEAAQPEQDEYDIPRHLLA-------PGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVK--GPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPA 332

HSP 2 Score: 93.9745 bits (232), Expect = 3.168e-19
Identity = 52/165 (31.52%), Postives = 84/165 (50.91%), Query Frame = 0 
Query: 1208 RSASLPWDDKLKNVFSFEDNGPKSPNAISPLDHRDIESLEFFCRQVESQVLLLRESMKNLTEAVENQEEPVVFVSHSKFIILTAHKVVHSGQEISERLIHTDIKSKIKEHTTHLTVCIRGVVSATKTAALEYPETTALMEMISSVLALGDAVRIIHRECRQALNA 1372
            +  S P D  L N   +    P +P     L   D + L F+  Q E+ +  L  ++     AV   + P +FV+HSKF+IL+AHK+V  G  +S +    D++S++  ++  L   +RG+V+ TK AAL+YP  +A  +M+  V  LG + +   R   Q   A
Sbjct:  709 QEVSRPIDHDLAN---WTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLAAA 870
The following BLAST results are available for this feature:
BLAST of Breast cancer anti estrogen resistance protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
BCAR14.365e-2630.99Breast cancer anti-estrogen resistance protein 1 O... [more]
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