TCONS_00047677-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00047677-protein
Unique NameTCONS_00047677-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length700

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00047677-protein ID=TCONS_00047677-protein|Name=TCONS_00047677-protein|organism=Clytia hemisphaerica|type=polypeptide|length=700bp
MSTRKVYSSQGKSSYHLGGAHKDISANAKPSDSVPHNGVSYDDLKKHCLK
QGVLFEDPDFPAVDQSMFFSRKPPRPFVWKRPKELVSDPKMFVGGASRFD
ITQGMLGDCWLLAAVAALCQYEGLLYQVVPPDQSFSSSDYCGIVRFRFWQ
YGRWEEVVVDDRLPTYNNKLVFLHSAQNNEFWSALLEKAYAKLCGSYESL
KGGQTSEAMEDFTGGVTETFNTAKPPAKFYSLLMKAQERQSLMCCSIEAK
PNEIEAKLNNGLIKGHAYTITSVQKAHVRGQEIELIRIRNPWGNEREWTG
AWSDGSNEWKMLSDSEKKELGISYDDDGEFWMSFQDFCANYTKVEVCMLS
PDSAGESDKKRWEMQINQGTWQQHVSAGGCRNFPDSFHLNPQYIVKLEDG
DDDDDNCTIVIGLIQKGRRKQKRVGAQNLTIGFSVYKLDDDKDEYMQDDR
LSKDFFLYHKSHARSHNFVNSREVTGRFSFEPGEYVIIPSTFKANEEGDF
IMRMFSEKAHAGGSMDTKTQIEYKPKVLSQSEKDSFDSKFKPFFEKVAGN
DGEIDAFELQAVLNSAFKKEMNGKSFSLEACRSMVAMVDRDRNGKLDYEE
FRTMWTTVMRYKANFAQYDKDQSGDMSATELRDALAKLGFKLSTPVLSSL
TLRYANKKGQVNIDDYLQICCRVKSSFESYLSYQGKSFSLDDYIMSAVYT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_030360XLOC_030360Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00047677TCONS_00047677Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR022684Calpain_cysteine_protease
IPR022683Calpain_III
IPR002048EF_hand_dom
IPR001300Peptidase_C2_calpain_cat
IPR022682Calpain_domain_III
IPR018247EF_Hand_1_Ca_BS
IPR000169Pept_cys_AS
IPR033883C2_III
IPR011992EF-hand-dom_pair
Vocabulary: Cellular Component
TermDefinition
GO:0005622intracellular
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Molecular Function
TermDefinition
GO:0004198calcium-dependent cysteine-type endopeptidase activity
GO:0005509calcium ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0005622 intracellular
molecular_function GO:0004198 calcium-dependent cysteine-type endopeptidase activity
molecular_function GO:0005509 calcium ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR022684Peptidase C2, calpain familyPRINTSPR00704CALPAINcoord: 140..165
score: 64.1
coord: 170..193
score: 78.75
coord: 103..119
score: 69.02
coord: 326..347
score: 59.39
coord: 479..507
score: 52.64
coord: 39..62
score: 47.08
coord: 195..222
score: 64.05
coord: 79..101
score: 55.07
coord: 376..393
score: 67.04
IPR022683Peptidase C2, calpain, domain IIISMARTSM007202calcoord: 361..513
e-value: 1.2E-65
score: 234.1
IPR002048EF-hand domainSMARTSM00054efh_1coord: 610..638
e-value: 1.3
score: 16.9
coord: 580..608
e-value: 0.0099
score: 25.1
IPR002048EF-hand domainPFAMPF13833EF-hand_8coord: 551..606
e-value: 2.7E-8
score: 33.4
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 550..569
score: 5.726
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 576..611
score: 12.17
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 615..641
score: 10.078
IPR002048EF-hand domainCDDcd00051EFhcoord: 550..606
e-value: 3.05306E-8
score: 50.2389
IPR001300Peptidase C2, calpain, catalytic domainSMARTSM00230cys_prot_2coord: 36..359
e-value: 8.6E-172
score: 586.7
IPR001300Peptidase C2, calpain, catalytic domainPFAMPF00648Peptidase_C2coord: 55..347
e-value: 6.3E-127
score: 422.6
IPR001300Peptidase C2, calpain, catalytic domainPROSITEPS50203CALPAIN_CATcoord: 54..350
score: 77.521
IPR001300Peptidase C2, calpain, catalytic domainCDDcd00044CysPccoord: 44..347
e-value: 3.57935E-138
score: 410.184
NoneNo IPR availableGENE3D1.10.238.10coord: 595..624
e-value: 1.1E-11
score: 43.8
NoneNo IPR availableGENE3D3.90.70.10coord: 215..360
e-value: 3.8E-54
score: 181.6
NoneNo IPR availableGENE3D2.60.120.380coord: 361..508
e-value: 3.1E-43
score: 146.9
NoneNo IPR availableGENE3D1.10.238.10coord: 625..680
e-value: 1.7E-8
score: 34.0
NoneNo IPR availableGENE3D1.10.238.10coord: 552..594
e-value: 9.4E-11
score: 41.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..36
NoneNo IPR availableSUPERFAMILY54001Cysteine proteinasescoord: 33..354
IPR022682Peptidase C2, calpain, large subunit, domain IIIPFAMPF01067Calpain_IIIcoord: 369..509
e-value: 9.1E-47
score: 158.8
IPR022682Peptidase C2, calpain, large subunit, domain IIISUPERFAMILY49758Calpain large subunit, middle domain (domain III)coord: 362..509
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 589..601
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 619..631
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 103..114
IPR033883Calpain subdomain IIICDDcd00214Calpain_IIIcoord: 360..508
e-value: 5.83875E-58
score: 192.899
IPR011992EF-hand domain pairSUPERFAMILY47473EF-handcoord: 537..681

Blast
BLAST of TCONS_00047677-protein vs. Swiss-Prot (Human)
Match: CAN9 (Calpain-9 OS=Homo sapiens GN=CAPN9 PE=1 SV=1)

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 317/672 (47.17%), Postives = 455/672 (67.71%), Query Frame = 0
Query:   26 ANAKPSDS-VPHN-GVSYDDLKKHCLKQGVLFEDPDFPAVDQSMFFSRKPPRPFVWKRPKELVSDPKMFVGGASRFDITQGMLGDCWLLAAVAALCQYEGLLYQVVPPDQSFSSSDYCGIVRFRFWQYGRWEEVVVDDRLPTYNNKLVFLHSAQNNEFWSALLEKAYAKLCGSYESLKGGQTSEAMEDFTGGVTETFNTAKPPAKFYSLLMKAQERQSLMCCSIEAK-PNEIEAKLNNGLIKGHAYTITSVQKAHVRGQEIELIRIRNPWGNEREWTGAWSDGSNEWKMLSDSEKKELGISYDDDGEFWMSFQDFCANYTKVEVCMLSPDSAGESDKKRWEMQINQGTWQQHVSAGGCRNFPDSFHLNPQYIVKLEDGDDDDDNCTIVIGLIQKGRRKQKRVGAQNLTIGFSVYKLDDDKDEYMQDDRLSKDFFLYHKSHARSHNFVNSREVTGRFSFEPGEYVIIPSTFKANEEGDFIMRMFSEKAHAGGSMDTKTQIEYKPKVLSQS--EKDSFDSKFKPFFEKVAGNDGEIDAFELQAVLNSAFK--KEMNGKSFSLEACRSMVAMVDRDRNGKLDYEEFRTMWTTVMRYKANFAQYDKDQSGDMSATELRDALAKLGFKLSTPVLSSLTLRYANKKGQVNIDDYLQICCRVKSSFESY--LSYQGKSF 688
            A+  P D+ + H+ G S++ +++ CL++G LFED DFPA + S+F+S +P  PFVWKRP E+V +P+  +GGA+R DI QG LGDCWLLAA+A+L   +  L +V+P DQSF    Y GI  F+FWQ+  W +VV+DDRLPT+ ++LVFLHSA +NEFWSALLEKAYAKL GSYE+LKGG   EAMEDFTGGV ETF T + P  FY +L KA +R SL+ C I+ +   E EA+   GLIKGHAY++T + +   RGQ IELIRIRNPWG + EW G+WSD S EW+ +  +E+K L  +  DDGEFWM+F+DF A++ KVE+C L+PD+  E    +WE+ ++QG+W +  +AGGCRNF D+F  NPQ  + L + D+  + C+ ++ L+QK RRK KR GA  LTIG+++Y+  D      +D+ L+KDFF YH S ARS  F+N REV+ RF   PGEY++IPSTF+ ++E DF +R+FSEK      MD    I+           ++   + +F+  FE+VAG D E+ A EL+ VLN+  +  K++  K  SL +C+++++++D   NGKL+++EF+  W  + ++   F ++D D+SG MS  ELR AL   GF+LS+ +L  + LRYA+++ Q++ DD+L    R++++   +  LS + K F
Sbjct:   12 AHPVPKDARITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPG-YAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGHAYSVTGIDQVSFRGQRIELIRIRNPWG-QVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDALEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD------KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEF 675          
The following BLAST results are available for this feature:
BLAST of TCONS_00047677-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CAN90.000e+047.17Calpain-9 OS=Homo sapiens GN=CAPN9 PE=1 SV=1[more]
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