Glycyl tR synthetase (polypeptide) - C. hemisphaerica

Overview
NameGlycyl tR synthetase
Unique NameTCONS_00045564-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length741

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00045564-protein ID=TCONS_00045564-protein|Name=Glycyl tR synthetase|organism=Clytia hemisphaerica|type=polypeptide|length=741bp
MVLNSVSRSLVRLNKVFRVIENHFVRFPSKRHSTASADHLQVFKRYKGNY
FSTRSSSLLEKMTDIAELEQQVKNCRISVKEQGDLVKKLKGEKALTADID
IAVKELKARKRVLEQKELQLDPPDNFDRGKCEDLLKRRFFYAPAFEIYGG
VAGLYDFGPMGCAMENNLVKIWRNHFVLEEQLLEVRCTQMTPQQVLKSSG
HVDRFTDVMVRDVKTGDCYRADHLLEGHLEKLCLSKKTSGEKKKEYQLVM
NKMETYKREELWELIQKYECKAPVTNNDLCDPQDFNLMFATSIGPSGLIP
GFLRPETAQGIFLNFKRLLDYNNGRLPFGGAQIGCGFRNEIAPRAGLLRV
REFLMAEIEYFVDPDKKEMSKFSTVENTTCRIYSRDAQMSGEPAVMMSLK
DAHSKGIINNTAVGYFLGRICEFMLKIGVDPKKMRFRQHMANEMAHYACD
CWDCELKTSYGWIECIGCADRACFDLQQHTNASGEKLVAMVDLAEPVSMD
VVEVVLNKPIVGKAFKKEAKVVTEHVSKLNDEQTAQLESDINSNGSHTFT
IDGKEYQLTKEMLKEVRRFKKDVHVREVQPHVIEPSFGIGRIMYSVLEHN
FKVREGDEQRTWLSLPPLLAPVKCSVLPLSKNEAFDPFIKQISTALTEYD
ISHKVDDSSGSIGRRYARTDEIAIPYGVTIDFDTVNNTPHTATLRERNTT
RQIRAELDDIPDLVNQLIRGKKSWQNVEQHYGLFEGQTTNK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_029134XLOC_029134Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00045564TCONS_00045564Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002315tRNA-synt_gly
IPR000738WHEP-TRS_dom
IPR004154Anticodon-bd
IPR002314aa-tRNA-synt_IIb
IPR006195aa-tRNA-synth_II
IPR033731GlyRS-like_core
Vocabulary: Biological Process
TermDefinition
GO:0006426glycyl-tRNA aminoacylation
GO:0006418tRNA aminoacylation for protein translation
Vocabulary: Cellular Component
TermDefinition
GO:0005737cytoplasm
Vocabulary: Molecular Function
TermDefinition
GO:0005524ATP binding
GO:0004820glycine-tRNA ligase activity
GO:0000166nucleotide binding
GO:0004812aminoacyl-tRNA ligase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006426 glycyl-tRNA aminoacylation
biological_process GO:0006418 tRNA aminoacylation for protein translation
cellular_component GO:0005737 cytoplasm
molecular_function GO:0004812 aminoacyl-tRNA ligase activity
molecular_function GO:0005524 ATP binding
molecular_function GO:0004820 glycine-tRNA ligase activity
molecular_function GO:0000166 nucleotide binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002315Glycyl-tRNA synthetasePRINTSPR01043TRNASYNTHGLYcoord: 351..361
score: 68.18
coord: 283..295
score: 62.82
coord: 334..351
score: 62.04
coord: 147..161
score: 67.78
coord: 580..592
score: 74.36
coord: 302..319
score: 77.16
coord: 662..681
score: 62.78
IPR002315Glycyl-tRNA synthetaseTIGRFAMTIGR00389TIGR00389coord: 128..716
e-value: 9.5E-207
score: 685.9
IPR000738WHEP-TRS domainSMARTSM00991WHEP_TRS_a_2_a_3_acoord: 75..130
e-value: 1.7E-4
score: 31.0
IPR000738WHEP-TRS domainPFAMPF00458WHEP-TRScoord: 78..117
e-value: 1.2E-8
score: 34.9
IPR000738WHEP-TRS domainPROSITEPS00762WHEP_TRS_1coord: 82..110
IPR000738WHEP-TRS domainPROSITEPS51185WHEP_TRS_2coord: 71..127
score: 10.793
NoneNo IPR availableGENE3D1.10.287.10coord: 64..119
e-value: 5.5E-8
score: 32.2
NoneNo IPR availableGENE3D3.30.930.10coord: 243..614
e-value: 4.1E-94
score: 314.6
coord: 125..239
e-value: 8.6E-21
score: 73.6
NoneNo IPR availableCDDcd00858GlyRS_anticodoncoord: 596..719
e-value: 1.8099E-53
score: 179.676
NoneNo IPR availableSUPERFAMILY55681Class II aaRS and biotin synthetasescoord: 130..366
coord: 553..626
coord: 409..487
IPR004154Anticodon-bindingPFAMPF03129HGTP_anticodoncoord: 623..716
e-value: 8.3E-19
score: 67.5
IPR004154Anticodon-bindingGENE3D3.40.50.800coord: 615..735
e-value: 3.1E-21
score: 75.1
IPR004154Anticodon-bindingSUPERFAMILY52954Class II aaRS ABD-relatedcoord: 610..733
IPR002314Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)PFAMPF00587tRNA-synt_2bcoord: 303..600
e-value: 6.9E-11
score: 42.3
IPR006195Aminoacyl-tRNA synthetase, class IIPROSITEPS50862AA_TRNA_LIGASE_IIcoord: 249..621
score: 9.343
IPR033731Glycyl-tRNA synthetase-like core domainCDDcd00774GlyRS-like_corecoord: 132..477
e-value: 6.42112E-106
score: 325.314

Blast
[Close]
BLAST of Glycyl tR synthetase vs. Swiss-Prot (Human)
Match: GARS (Glycine--tRNA ligase OS=Homo sapiens GN=GARS PE=1 SV=3)

HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0
Identity = 398/679 (58.62%), Postives = 514/679 (75.70%), Query Frame = 0 
Query:   64 DIAELEQQVKNCRISVKEQGDLVKKLKGEKALTADIDIAVKELKARKRVLEQKELQLDPPDNF-DRGKCEDLLKRRFFYAPAFEIYGGVAGLYDFGPMGCAMENNLVKIWRNHFVLEEQLLEVRCTQMTPQQVLKSSGHVDRFTDVMVRDVKTGDCYRADHLLEGHLEKLCLSKKTSGEKKKEYQLVMNKMETYKREELWELIQKYECKAPVTNNDLCDPQDFNLMFATSIGPSGLIPGFLRPETAQGIFLNFKRLLDYNNGRLPFGGAQIGCGFRNEIAPRAGLLRVREFLMAEIEYFVDPDKKEMSKFSTVENTTCRIYSRDAQMSGEPAVMMSLKDAHSKGIINNTAVGYFLGRICEFMLKIGVDPKKMRFRQHMANEMAHYACDCWDCELKTSYGWIECIGCADRACFDLQQHTNASGEKLVAMVDLAEPVSMDVVEVVLNKPIVGKAFKKEAKVVTEHVSKLNDEQTAQLESDINSNGSHTFTIDGKEYQLTKEMLKEVRRFKKDVHVREVQPHVIEPSFGIGRIMYSVLEHNFKVREGDEQRTWLSLPPLLAPVKCSVLPLSKNEAFDPFIKQISTALTEYDISHKVDDSSGSIGRRYARTDEIAIPYGVTIDFDTVNNTPHTATLRERNTTRQIRAELDDIPDLVNQLIRGKKSWQNVEQHYGLFEGQTTNK 741
            D A  E+ +   R++V++QGDLV+KLK +KA   D+D AV ELKARKRVLE KEL L P D+  DR K ED LKRRFFY  AF IYGGV+GLYDFGP+GCA++NN+++ WR HF+ EEQ+LE+ CT +TP+ VLK+SGHVD+F D MV+DVK G+C+RADHLL+ HL+KL   KK S EKK E + V+ +++ Y ++EL +L   Y  K+P+T NDL  P  FNLMF T IGP G +PG+LRPETAQGIFLNFKRLL++N G+LPF  AQIG  FRNEI+PR+GL+RVREF MAEIE+FVDP +K+  KF  V +    +YS  AQ+SG+ A  M L DA  +G+INNT +GYF+GRI  ++ K+G+ P K+RFRQHM NEMAHYACDCWD E KTSYGWIE +GCADR+C+DL  H  A+   LVA   L EP +++VV+   +K  +GKA+KK+AK+V E+++  ++    ++E  +N  G  T   +GK +QLTK+M+  V+RF+K ++V EV P+VIEPSFG+GRIMY+V EH F VREGDEQRT+ S P ++AP KCSVLPLS+N+ F PF+K++S ALT + +SHKVDDSSGSIGRRYARTDEI + +GVTIDFDTVN TPHTATLR+R++ RQIRAE+ ++P +V  L  G  +W +VE  Y LFEGQ T K
Sbjct:   56 DGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMIN-VKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGK 733
The following BLAST results are available for this feature:
BLAST of Glycyl tR synthetase vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GARS0.000e+058.62Glycine--tRNA ligase OS=Homo sapiens GN=GARS PE=1 ... [more]
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