TCONS_00020927-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00020927-protein
Unique NameTCONS_00020927-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length894

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00020927-protein ID=TCONS_00020927-protein|Name=TCONS_00020927-protein|organism=Clytia hemisphaerica|type=polypeptide|length=894bp
MELKDFILCSVCILMKFSWVSTLKGNIEPDDLLTHISGHQISTNDVISFL
EVFKGIHYELQKQTIEMQRLNKRMFQCDFCSSKNSILDNKVFVATCEQSN
CFDKDSCKIDPSSISGXNCFDKDSCKIDPSSISGYSCGPCPKGYEGDGIT
CKDIDECKSNNVCSNLTKCINKEPGHKCSPCPAGYKEVLRHEKGYTKQEC
VDVDECSLNRDECPDGAECINGVGSYECRCKEGYESDGETCVDINECLEN
PCSEHAKCINRSPGFQCTKCRFGYEGEQIKGLGREFARNNKQVCKDKNEC
MNGEHACHEHAICTNTEGDYTCACPMGMRGDGFTCTDIDECKYARPCSPM
TSCVNLPDGKGFTCTKCPDGYFDTGASGAGIEVAKGVQQSCIDIDECTLK
PPKCDARNSICINREGSYKCICKEGFHNVNGTCRFIGYCQNYNCGPLSVC
VNDRQQKKAVCKCRPGYAGNGIVCGTDYDSDGWPDNDLPCNEERCTADNC
KYFPNSDQSDVDGDGKGDGCDDDADADGIYNKNDNCVLTPNPKQEDRDLD
RVGDKCDNCISMRNFHQLDTDGDGLGDVCDPDRDNDKLRNEKDNCDLIKN
PNQKDTDGDGIGDACDNCRDVKNYDQRDLNLNGIGDACDDFDDEDLDSVP
DDYDNCRQIANTDQADTDSDGIGDACDDDTDNDGILDEFDNCVFKFNPLQ
DDLDGNEIGDICDGDIDDDGIGDEDDDCPKHRNVTIIDFKTLIYVPLDPH
GAAQLDPVWSILNDGHDVHQALNSDPGIAVAPNQLGSMDFTGTFYVNTKR
DDDYIGFIFGYQSSSKFYAVMWKQKNQTYWDTTPFPATATAGVSIKVVNS
KSGPGKRLRNALWHTGNTTDEVSLLWHDKRXVMHYGIRGTLQMK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_011740XLOC_011740Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00020927TCONS_00020927Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000742EGF-like_dom
IPR001881EGF-like_Ca-bd_dom
IPR008859Thrombospondin_C
IPR024731EGF_dom
IPR003367Thrombospondin_3-like_rpt
IPR028974TSP_type-3_rpt
IPR013032EGF-like_CS
IPR018097EGF_Ca-bd_CS
IPR000152EGF-type_Asp/Asn_hydroxyl_site
IPR017897Thrombospondin_3_rpt
IPR009030Growth_fac_rcpt_
IPR013320ConA-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005509calcium ion binding
Vocabulary: Biological Process
TermDefinition
GO:0007155cell adhesion
Vocabulary: Cellular Component
TermDefinition
GO:0005576extracellular region
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007155 cell adhesion
cellular_component GO:0005576 extracellular region
molecular_function GO:0005509 calcium ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000742EGF-like domainSMARTSM00181egf_5coord: 246..295
e-value: 0.0013
score: 28.0
coord: 106..152
e-value: 22.0
score: 12.1
coord: 438..475
e-value: 6.3
score: 15.8
coord: 299..336
e-value: 4.5E-4
score: 29.5
coord: 396..434
e-value: 0.013
score: 24.7
coord: 156..201
e-value: 0.53
score: 19.3
coord: 340..392
e-value: 1.1
score: 18.3
coord: 205..242
e-value: 6.3E-4
score: 29.1
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 393..432
score: 10.479
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 153..179
score: 6.547
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 296..334
score: 13.651
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 435..475
score: 8.863
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 243..277
score: 10.924
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 337..377
score: 8.29
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 202..242
score: 14.775
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 337..392
e-value: 4.5E-4
score: 28.8
coord: 243..295
e-value: 2.8E-7
score: 40.2
coord: 202..242
e-value: 7.0E-11
score: 52.2
coord: 153..201
e-value: 1.3E-7
score: 41.2
coord: 393..434
e-value: 5.7E-9
score: 45.8
coord: 296..336
e-value: 4.8E-8
score: 42.7
coord: 103..152
e-value: 1.6
score: 0.2
IPR001881EGF-like calcium-binding domainPFAMPF07645EGF_CAcoord: 393..433
e-value: 9.9E-10
score: 38.4
coord: 337..372
e-value: 8.0E-5
score: 22.7
coord: 202..241
e-value: 1.7E-10
score: 40.8
coord: 243..276
e-value: 2.2E-6
score: 27.6
coord: 153..190
e-value: 2.0E-6
score: 27.8
NoneNo IPR availableGENE3D2.60.120.200coord: 740..885
e-value: 6.3E-49
score: 166.1
NoneNo IPR availableGENE3D2.10.25.10coord: 244..265
e-value: 3.8E-10
score: 39.0
coord: 204..225
e-value: 5.6E-10
score: 38.5
NoneNo IPR availableGENE3D2.10.25.10coord: 342..364
e-value: 4.9E-6
score: 26.0
NoneNo IPR availableGENE3D2.10.25.10coord: 392..417
e-value: 7.4E-11
score: 41.5
coord: 156..176
e-value: 2.8E-6
score: 26.9
coord: 437..459
e-value: 0.17
score: 11.6
NoneNo IPR availableGENE3D2.10.25.10coord: 297..318
e-value: 5.0E-9
score: 35.4
NoneNo IPR availableGENE3D2.10.25.10coord: 418..436
e-value: 3.2E-4
score: 20.0
coord: 365..391
e-value: 5.0E-5
score: 22.6
coord: 139..155
e-value: 4.1E-5
score: 22.9
coord: 226..243
e-value: 2.3E-11
score: 42.9
NoneNo IPR availableGENE3D2.40.155.10coord: 177..203
e-value: 2.0E-6
score: 27.0
coord: 266..296
e-value: 2.5E-7
score: 29.9
NoneNo IPR availableGENE3D2.10.25.10coord: 93..138
e-value: 0.25
score: 11.1
NoneNo IPR availableGENE3D2.10.25.10coord: 319..341
e-value: 1.8E-12
score: 46.9
NoneNo IPR availableCDDcd00054EGF_CAcoord: 393..427
e-value: 5.73603E-4
score: 37.6162
NoneNo IPR availableCDDcd00054EGF_CAcoord: 153..185
e-value: 6.23881E-4
score: 37.6162
NoneNo IPR availableCDDcd00054EGF_CAcoord: 296..331
e-value: 4.13618E-4
score: 38.0014
NoneNo IPR availableCDDcd00054EGF_CAcoord: 243..276
e-value: 6.12342E-4
score: 37.6162
NoneNo IPR availableCDDcd00054EGF_CAcoord: 202..242
e-value: 1.60246E-5
score: 42.2386
IPR008859Thrombospondin, C-terminalPFAMPF05735TSP_Ccoord: 754..881
e-value: 2.6E-53
score: 180.8
IPR008859Thrombospondin, C-terminalPROSITEPS51236TSP_CTERcoord: 740..894
score: 58.728
IPR024731EGF domainPFAMPF12947EGF_3coord: 300..335
e-value: 1.9E-9
score: 37.5
IPR003367Thrombospondin, type 3-like repeatPFAMPF02412TSP_3coord: 510..544
e-value: 1.4E-8
score: 34.1
coord: 569..603
e-value: 1.8E-7
score: 30.6
coord: 666..698
e-value: 7.6E-11
score: 41.4
coord: 627..664
e-value: 9.6E-7
score: 28.3
coord: 702..734
e-value: 4.1E-5
score: 23.1
IPR028974TSP type-3 repeatGENE3D4.10.1080.10coord: 460..554
e-value: 3.1E-16
score: 58.8
coord: 621..739
e-value: 2.9E-24
score: 84.9
coord: 555..620
e-value: 2.0E-16
score: 59.4
IPR028974TSP type-3 repeatSUPERFAMILY103647TSP type-3 repeatcoord: 546..616
IPR028974TSP type-3 repeatSUPERFAMILY103647TSP type-3 repeatcoord: 614..734
IPR028974TSP type-3 repeatSUPERFAMILY103647TSP type-3 repeatcoord: 470..557
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 228..241
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 461..474
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 243..267
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 393..420
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 313..324
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 219..230
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 411..422
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 568..603
score: 16.19
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 604..626
score: 12.396
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 476..508
score: 9.72
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 701..736
score: 13.655
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 509..544
score: 15.637
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 545..567
score: 9.963
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 665..700
score: 16.306
IPR017897Thrombospondin, type 3 repeatPROSITEPS51234TSP3coord: 627..664
score: 14.688
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 200..338
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 291..439
IPR013320Concanavalin A-like lectin/glucanase domainSUPERFAMILY49899Concanavalin A-like lectins/glucanasescoord: 738..881

Blast
BLAST of TCONS_00020927-protein vs. Swiss-Prot (Human)
Match: TSP4 (Thrombospondin-4 OS=Homo sapiens GN=THBS4 PE=1 SV=2)

HSP 1 Score: 485.337 bits (1248), Expect = 3.735e-157
Identity = 294/589 (49.92%), Postives = 364/589 (61.80%), Query Frame = 0
Query:  305 HACHEHAICTNTEGDYTCA-CPMGMRGDGFTCTDIDECKYARPCSPMTSCVNLPDGKGFTCTKCPDGYFDTGASGAGIEVAKGVQQSCIDIDECTLKPPKCDARNSICINREGSYKC-ICKEGFH--NVNGTCRFIGYCQNYNCGPLSV---CVNDRQQKKAVCKCRPGYAGNGIVCGTDYDSDGWPDNDLPCNEERCTADNCKYFPNSDQSDVDGDGKGDGCDDDADADGIYNKNDNCVLTPNPKQEDRDLDRVGDKCDNCISMRNFHQLDTDGDGLGDVCDPDRDNDKLRNEKDNCDLIKNPNQKDTDGDGIGDACDNCRDVKNYDQRDLNLNGIGDACDDFDDEDLDSVPDDYDNCRQIANTDQADTDSDGIGDACDDDTDNDGILDEF----DNCVFKFNPLQDDLDGNEIGDICDGDIDDDGIGDEDDDCPKHRNVTIIDFKTLIYVPLDPHGAAQLDPVWSILNDGHDVHQALNSDPGIAVAPNQLGSMDFTGTFYVNTKRDDDYIGFIFGYQSSSKFYAVMWKQKNQTYWDTTPFPATATAGVSIKVVNSKSGPGKRLRNALWHTGNTTDEVSLLWHDKRXV 882
            + C     CT++   + C  CP G  G+G TC D+DECKY  PC P   C+NL    GF C  CP G+      G GI  AK  +Q C DIDEC  +   C   NSIC+N  GSY+C  CK G+    + G C+    C+N    P SV   C+ +RQ     C C  G+AG+G +CG D D D +PD +LPC+   C  DNCKY PNS Q D D DG GD CD+DAD DGI N+ DNCVL  N  Q + D D  GD CDNC+S+ N  Q DTDGDG GD CD D D D ++N  DNC    N +Q+D DGDG+GDACD+C DV N +Q D++ + +GD+CD   D D D   D  DNC  + N+ Q DTD DGIGD CDDD DNDGI D      DNC    NP Q+D + + +GDIC+ D D D + D  D CP++  VT+ DF+    V LDP G AQ+DP W +LN G ++ Q +NSDPG+AV       +DF GTF+VNT+ DDDY GFIFGYQ SS FY VMWKQ  QTYW  TPF A A  G+ +K V SK+GPG+ LRN+LWHTG+T+D+V LLW D R V
Sbjct:  293 NPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINL--SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGAC-VPNSICVNTLGSYRCGPCKPGYTGDQIRG-CKAERNCRNPELNPCSVNAQCIEERQ-GDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNV 873          

HSP 2 Score: 161.77 bits (408), Expect = 1.103e-40
Identity = 170/506 (33.60%), Postives = 212/506 (41.90%), Query Frame = 0
Query:  213 CPDGAECINGVGSYEC-RCKEGYESDGETCVDINECLENPCSEHAKCINRSPGFQCTKCRFGYEGEQIKGLGREFARNNKQVCKDKNECMNGEHACHEHAICTNTEGDYTCA-CPMGMRGDGFTCTDIDECKYAR--------PCSPMTSCVNLPDGKGFTCTKCPDGYFDTGASGAGIEVAKGVQQSCIDIDECTLKPPKCDARNSICINREGSYKCICKEGFHNVNGTCRFIGYCQNYNCGPLSVCVNDRQQKKAVCKCRPGYAGNGIVCGTDYDSDGWPDNDLPCNEERCTADNCKYFPNSDQSDVDGDGKGDGCDD----------DADADG-------------IYNKNDNCVLTPNPKQEDRDLDRVGDKCDNCISMRNFHQLDTDGDGLGDVCDP--DRDNDKLRNEKDNCDLIKNPNQKDTDGDG-----------------IGDACDNCRDVKNYDQRDLNLNGIGDACDDFDDEDLDSVPDDYDNCRQIANTDQAD 666
            C  G +C +    ++C  C EGY  +G TC+D++EC  +PC     CIN SPGF+C  C  G+ G  ++G+G  FA++NKQVC D +EC NG  AC  ++IC NT G Y C  C  G  GD      I  CK  R        PCS    C+    G   TC  C  G+     +G G    K V     DID    +   C ARN                              C+  NC      V +  Q+ A         G G  C  D D DG        NE+    DNC    N DQ + D D  GD CD+          D D DG             I N  DNC   PN  Q D+D D VGD CD+C  + N +Q D D D +GD CD   D D D  ++  DNC  + N  Q DTD DG                 +    DNCR V N  Q D N +G+GD C+   D D D V D  D C + A     D
Sbjct:  295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPCKPGYTGD-----QIRGCKAERNCRNPELNPCSVNAQCIEERQGD-VTCV-CGVGW-----AGDGYICGKDV-----DIDSYPDEELPCSARN------------------------------CKKDNCK----YVPNSGQEDA------DRDGIGDACDEDADGDGI------LNEQ----DNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICE--SDFDQDQVIDRIDVCPENAEVTLTD 729          

HSP 3 Score: 97.4413 bits (241), Expect = 1.282e-20
Identity = 62/157 (39.49%), Postives = 79/157 (50.32%), Query Frame = 0
Query:  131 SISGYSCGPCPKGYEGDGITCKDIDECKSNNVCSNLTKCINKEPGHKCSPCPAGYKEVLRHEKGYT-----KQECVDVDECSLNRDECPDGAECINGVGSYEC-RCKEGYESDG-ETCVDINECLE---NPCSEHAKCINRSPGFQCTKCRFGYEGE 277
            S  G+ CGPCP+GY G+GITC D+DECK +  C     CIN  PG +C  CP G+   +    G +     KQ C D+DEC      C   + C+N +GSY C  CK GY  D    C     C     NPCS +A+CI    G     C  G+ G+
Sbjct:  304 SRDGFQCGPCPEGYTGNGITCIDVDECKYHP-CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGD 457          
The following BLAST results are available for this feature:
BLAST of TCONS_00020927-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TSP43.735e-15749.92Thrombospondin-4 OS=Homo sapiens GN=THBS4 PE=1 SV=... [more]
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