TCONS_00011800-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00011800-protein
Unique NameTCONS_00011800-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length253

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00011800-protein ID=TCONS_00011800-protein|Name=TCONS_00011800-protein|organism=Clytia hemisphaerica|type=polypeptide|length=253bp
MSCSNHEIIFDPFDLLRNGENGIQQKILLLVLNLPFTVNSTFTTLWKKSC
TKFCCDGGSNRLFDASKDSENFIPDFICGDLDSLKETTKTYYLQKNVKLE
FLYDQDNTDFTKTAMFALEECHQKGIEFDCLVAYPAFGGRLDQTMANINT
MFQLKEKTKKPCYLITDDDIAFLVDKGKTRIKVERELKGGWCSLIPIACK
AEKVTTTGFKWNLDGDSMEFGSLVSTSNAFGENVDHVTVDTSHPLLITFG
IKS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006618XLOC_006618Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00011800TCONS_00011800Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR007373Thiamin_PyroPKinase_B1-bd
IPR007371TPK_catalytic
IPR006282Thi_PPkinase
IPR016966Thiamin_pyrophosphokinase_euk
Vocabulary: Biological Process
TermDefinition
GO:0009229thiamine diphosphate biosynthetic process
GO:0006772thiamine metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0030975thiamine binding
GO:0005524ATP binding
GO:0004788thiamine diphosphokinase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0009229 thiamine diphosphate biosynthetic process
biological_process GO:0006772 thiamine metabolic process
molecular_function GO:0005524 ATP binding
molecular_function GO:0030975 thiamine binding
molecular_function GO:0004788 thiamine diphosphokinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007373Thiamin pyrophosphokinase, vitamin B1-binding domainSMARTSM00983TPK_B1_binding_a_2_acoord: 177..245
e-value: 5.3E-16
score: 69.2
IPR007373Thiamin pyrophosphokinase, vitamin B1-binding domainPFAMPF04265TPK_B1_bindingcoord: 178..246
e-value: 9.4E-21
score: 73.2
IPR007373Thiamin pyrophosphokinase, vitamin B1-binding domainGENE3D2.60.120.320coord: 154..253
e-value: 2.1E-36
score: 124.2
IPR007373Thiamin pyrophosphokinase, vitamin B1-binding domainSUPERFAMILY63862Thiamin pyrophosphokinase, substrate-binding domaincoord: 168..252
IPR007371Thiamin pyrophosphokinase, catalytic domainGENE3D3.40.50.10240coord: 21..153
e-value: 2.7E-39
score: 133.7
IPR007371Thiamin pyrophosphokinase, catalytic domainPFAMPF04263TPK_catalyticcoord: 42..160
e-value: 1.3E-32
score: 112.3
IPR007371Thiamin pyrophosphokinase, catalytic domainCDDcd07995TPKcoord: 29..248
e-value: 4.3655E-59
score: 187.367
IPR007371Thiamin pyrophosphokinase, catalytic domainSUPERFAMILY63999Thiamin pyrophosphokinase, catalytic domaincoord: 24..159
IPR006282Thiamin pyrophosphokinaseTIGRFAMTIGR01378TIGR01378coord: 29..241
e-value: 2.3E-44
score: 149.3
IPR016966Thiamin pyrophosphokinase, eukaryoticPIRSFPIRSF031057TPK1coord: 5..253
e-value: 1.2E-58
score: 196.3

Blast
BLAST of TCONS_00011800-protein vs. Swiss-Prot (Human)
Match: TPK1 (Thiamin pyrophosphokinase 1 OS=Homo sapiens GN=TPK1 PE=1 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 6.338e-60
Identity = 102/249 (40.96%), Postives = 149/249 (59.84%), Query Frame = 0
Query:    7 EIIFDPFDLLRNGENGIQQKILLLVLNLPFTVNSTFTTLWKKSCTKFCCDGGSNRLFDASK-DSENFIPDFICGDLDSLKETTKTYYLQKNVKLEFLYDQDNTDFTKTAMFALEECHQKGIEFDCLVAYPAFGGRLDQTMANINTMFQLKEKTKKPCYLITDDDIAFLVDKGKTRIKVERELKGGWCSLIPIACKAEKVTTTGFKWNLDGDSMEFGSLVSTSNAF-GENVDHVTVDTSHPLLITFGIKS 253
            E  F P + L +  N    K  L++LN P  +++ F  LW K+  + C DGG+NRL+D ++ + E+F+P+FI GD DS++   + YY  K  +L    DQD+TDFTK      ++  +K ++ D +V      GR DQ MA++NT+FQ    T  P  +I ++ + +L+  GK R+ V+  ++G WC LIP+     +VTTTG KWNL  D + FG+LVSTSN + G  V  VTV+T HPLL T  IKS
Sbjct:    2 EHAFTPLEPLLSTGN---LKYCLVILNQP--LDNYFRHLWNKALLRACADGGANRLYDITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKVDVIVTLGGLAGRFDQIMASVNTLFQATHITPFPIIIIQEESLIYLLQPGKHRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGV--VTVETDHPLLWTMAIKS 243          
The following BLAST results are available for this feature:
BLAST of TCONS_00011800-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TPK16.338e-6040.96Thiamin pyrophosphokinase 1 OS=Homo sapiens GN=TPK... [more]
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