TCONS_00010714-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00010714-protein
Unique NameTCONS_00010714-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length567

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00010714-protein ID=TCONS_00010714-protein|Name=TCONS_00010714-protein|organism=Clytia hemisphaerica|type=polypeptide|length=567bp
LLKGWKRRHDEESQSPFSQSSFGAASNNEVAIHSQQPLNHLMFISMLEHI
CVLYTQDENASDALFKNVCEKLKSGMLIPDLAYLDDFKAVRMKYQSALKS
LMEGSVQTLQPKFELLKTKEHLAFNSSAVSGFHTQSLYNEMFSMEEHIAS
GGFGKVVKAQNKLDHKFYAIKKIPLVDTDVKKILQTLREVQIFSNLEHTN
IVRYHSSWLEHGVETFLQKDVHSNQEKNVRRTNIEKSATTEAEEKEFIPV
IFQQPIQSHGVFGVGISHLVHPPSHPPKLLGLPAGSNDEVNKEPSDNHIV
KKRPTLRFNNNAKLLKMTLFIQMELCSRTLRDWLHQRNNEYNEEIGIGVV
EVRDMARQISSAVHYIHRQGMLHRDMKPENVFLTYTAKQLTIKVGDFGLA
RYQPSPSNEPLSPVVDGNAPLFNFGNTEHTIGVGTATYAAPEQLKEPFYT
NKVDIWSLGIILYEMYKPFCTEMERGRSIQNLLYKRELADELSTKWQEEC
ELILKMTSLQPRDRPEASYLLKFFTQNPEKKSLSELEKTIKLQREIIEGL
RRQLKEQLCLKCHEPLL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006006XLOC_006006Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00010714TCONS_00010714Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 533..553
NoneNo IPR availableCOILSCoilCoilcoord: 566..567
NoneNo IPR availableGENE3D3.30.200.20coord: 123..329
e-value: 1.1E-24
score: 86.1
NoneNo IPR availableGENE3D1.10.510.10coord: 330..565
e-value: 8.0E-41
score: 139.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..22
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 142..524
e-value: 6.1E-41
score: 152.0
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 144..247
e-value: 8.9E-12
score: 44.8
coord: 316..522
e-value: 3.8E-34
score: 118.1
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 142..530
score: 36.626
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 371..383
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 135..214
coord: 314..530

Blast
BLAST of TCONS_00010714-protein vs. Swiss-Prot (Human)
Match: E2AK1 (Eukaryotic translation initiation factor 2-alpha kinase 1 OS=Homo sapiens GN=EIF2AK1 PE=1 SV=2)

HSP 1 Score: 172.94 bits (437), Expect = 1.048e-46
Identity = 154/548 (28.10%), Postives = 258/548 (47.08%), Query Frame = 0
Query:   61 SDALFKNVCEKLKSGMLIPDLAYLDDFKAVRMKYQSALKSLMEGSVQTLQ--PKFELLKTKEHLAFNSSAVSGFHTQSLYNEMFSMEEHIASGGFGKVVKAQNKLDHKFYAIKKIPLVDTDVKKILQTLREVQIFSNLEHTNIVRYHSSWLEH----------GVETFLQKDVHSNQEKNVRRTNIEKSATTEAEEKEFIPVIFQQPI-QSHGVFGVGISHLVHPPS--HPPKLLGLPAG---SNDEVNKEP----SDNHIVKKRPTLRFNN---------------NAKLLKMT-------LFIQMELCSRTLRDWLHQRNN---EYNEEIGIGVVEVR---DMARQISSAVHYIHRQGMLHRDMKPENVFLTYTAKQLTIKVGDFGLARYQPSPSNEPLSPVVDGNAPLFNFGNTE---HTIGVGTATYAAPEQLKEPFYTNKVDIWSLGIILYEMYKPFCTEMERGRSIQNLLYKRELADELSTKWQEECELILKMTSLQPRDRPEASYLLKF-FTQNPEKKSLSELEKTIKLQREIIEGLRRQL 554
            S  +FK +C+      L+      D+F ++R+ +  A+  LM  + + ++  P  ++ + ++     S  V+     S Y   F     +  GG+G+V K +NKLD ++YAIKKI +        ++ LREV++ + L+H NIV YH++W+EH                  +V S+QE++  +  ++   ++ +       +IF +P  +    FG   +   +  S  +   L+   +G   S  E+ +      S + IV+++  LR N+               N   L  T       L IQM+LC  +L DW+ +RN    EY +E     V       + +++   V YIH  G++HRD+KP N+FL    +Q  +K+GDFGLA           + ++  N    N        HT  VGT  YA+PEQL+   Y  K D++SLG++L E+++PF TEMER   +   L   +L + L  +   + + I  +T      RP A  LL+    QN    +L+   K I+ ++EI E L++QL
Sbjct:   87 SRQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCEDISRIQK---IRSREVALEAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQPRADRAAIELPSLEVLSDQEEDREQCGVKNDESSSSS------IIFAEPTPEKEKRFGESDTENQNNKSVKYTTNLVIRESGELESTLELQENGLAGLSASSIVEQQLPLRRNSHLEESFTSTEESSEENVNFLGQTEAQYHLMLHIQMQLCELSLWDWIVERNKRGREYVDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQ--VKIGDFGLA----------CTDILQKNTDWTNRNGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG-LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQSELFQNSGNVNLTLQMKIIEQEKEIAE-LKKQL 611          
The following BLAST results are available for this feature:
BLAST of TCONS_00010714-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
E2AK11.048e-4628.10Eukaryotic translation initiation factor 2-alpha k... [more]
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