TCONS_00010305-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00010305-protein
Unique NameTCONS_00010305-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1159

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00010305-protein ID=TCONS_00010305-protein|Name=TCONS_00010305-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1159bp
MGVKGLWRLVASAGKPVSLESLNGKILAVDVSIWLNKAAKGMRDKRGNAI
YNAHLVLMFHRICKLLFYGIKPVFVFDGGVPELKKKTLRLRRERRSQADS
NRKRTKDQILKNYLQTKALEAVTGVKSTTKLQLRDKKEKEDIFKLPEQPV
QNDSSDSSSDDDVLNEDEWLRTLNESRVQLMFDKAEKLDTSSAEFNALPA
EVKHELLTEIKDYQRRRYRRKNEAEVKLPQEAGTFSDFQLGNLMKRGQIT
HQIDELRKEMNSSMAAQFIELYHDVDQKKYKDKHIEGKRYVSNEKQGYVL
IKKNVKDKSQNVLFQSSLDDDYARFKKREDDAAENPADVFRKLEREPARF
QTIVEKNASRKRLKSDSSDEGSVVEVKIKVPRLTGPEAVTLSKDVTQDTA
KDEVELMSASSSEESETDDTVNVTERKMEGICTAEKVPSKSALSKEVVEP
TPNNQKEIVLLSNNDSSRESKTEASETFVGGKIDVSLAAKQEVKELTEIS
NDAVVTEPSSMVSAPSKMNSTVSRPPPNSIKIKSTSNTVDDSSAKISSAN
DGKIENVRNDKNIAVVTETNDFTKMSSSVTDNDNPSDAPPMIKPTLDLIT
DLITDKDTSTSLISPAISSSRTPSSNLSNPPETPMDSNEKDFPGEENIKQ
AEQQPAPSQPVSSQPAPSQPAPSQPAPQIPMEDLIGLQKDLEKEHDRLED
TTKKLKRQAATLSDETYQDVQELLRLFGIPYLVSPAEAEAQCAQLDFSKL
TDGSITDDSDIFLFGGHRVYKNIFDQKKYAEVYLLDDLIKKLYLTREKLI
ALAFMTGSDYTEGIRGIGAVTGMEVLHEFNKNKPKETLKFFRDWLRGKIK
DFNPGSNLKNKLRDVDMSQTFNSSLVWDAYLSPTVETSEEQFEWSNPDID
ALKEYASEKLGWLYNKTDELLLPVLENMKKRKERQKTLMAYFQPKVEDDI
ETNIKSNRLKKVLSKMSSKDYTENEAGPSGLSSKKSEKPEIFFEMDDNDV
DSDILKVSLNDIKPSGTRSTASASRPYNSKKLISTSQSKVDQSLPYIDDS
DVVSKRPRRSVKSSEPSTSSTISSNEHVQAMKVANLVKAAGESLKPTTPY
IAIQNVNNMVWNRMRGKNKQMKRGQRGGKSRRSKTTADLLEQVNTAKSSV
QSSDSESDH
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005785XLOC_005785Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00010305TCONS_00010305Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001044XPG/Rad2_eukaryotes
IPR006084XPG/Rad2
IPR008918HhH2
IPR006086XPG-I_dom
IPR006085XPG_DNA_repair_N
IPR029060PIN_domain-like
IPR019974XPG_CS
IPR0200455-3_exonuclease_C
Vocabulary: Biological Process
TermDefinition
GO:0006289nucleotide-excision repair
GO:0006281DNA repair
Vocabulary: Molecular Function
TermDefinition
GO:0003697single-stranded DNA binding
GO:0004519endonuclease activity
GO:0004518nuclease activity
GO:0003677DNA binding
GO:0003824catalytic activity
GO:0016788hydrolase activity, acting on ester bonds
Vocabulary: Cellular Component
TermDefinition
GO:0005634nucleus
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006281 DNA repair
biological_process GO:0006289 nucleotide-excision repair
cellular_component GO:0005634 nucleus
molecular_function GO:0003824 catalytic activity
molecular_function GO:0003677 DNA binding
molecular_function GO:0004519 endonuclease activity
molecular_function GO:0016788 hydrolase activity, acting on ester bonds
molecular_function GO:0004518 nuclease activity
molecular_function GO:0003697 single-stranded DNA binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 681..715
NoneNo IPR availableGENE3D1.10.150.20coord: 799..976
e-value: 1.3E-11
score: 44.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1012..1076
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 610..679
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 436..475
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 574..593
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 507..552
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 142..163
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1115..1159
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 966..987
NoneNo IPR availableCDDcd09868PIN_XPGcoord: 1..139
e-value: 5.11788E-57
score: 197.45
IPR001044XPG/Rad2 endonuclease, eukaryotesPRINTSPR00066XRODRMPGMNTGcoord: 2..19
score: 48.89
coord: 281..305
score: 36.0
coord: 824..844
score: 37.14
coord: 54..77
score: 66.67
coord: 96..118
score: 26.09
coord: 222..247
score: 30.0
IPR006084XPG/Rad2 endonucleasePRINTSPR00853XPGRADSUPERcoord: 799..814
score: 44.53
coord: 24..38
score: 46.88
coord: 745..765
score: 42.71
coord: 724..741
score: 58.85
coord: 72..91
score: 51.25
IPR008918Helix-hairpin-helix motif, class 2SMARTSM00279HhH_4coord: 796..829
e-value: 2.9E-9
score: 46.8
IPR006086XPG-I domainSMARTSM00484xpgineucoord: 725..794
e-value: 6.1E-27
score: 105.5
IPR006086XPG-I domainPFAMPF00867XPG_Icoord: 725..809
e-value: 2.0E-21
score: 76.0
IPR006085XPG N-terminalSMARTSM00485xpgn3coord: 1..98
e-value: 1.4E-46
score: 170.7
IPR006085XPG N-terminalPFAMPF00752XPG_Ncoord: 1..98
e-value: 1.9E-31
score: 108.5
IPR029060PIN domain-likeGENE3D3.40.50.1010coord: 4..798
e-value: 4.9E-70
score: 234.8
IPR029060PIN domain-likeSUPERFAMILY88723PIN domain-likecoord: 692..809
coord: 2..103
IPR019974XPG conserved sitePROSITEPS00841XPG_1coord: 70..84
IPR0200455'-3' exonuclease, C-terminal domainSUPERFAMILY478075' to 3' exonuclease, C-terminal subdomaincoord: 865..942
coord: 794..835

Blast
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BLAST of TCONS_00010305-protein vs. Swiss-Prot (Human)
Match: ERCC5 (DNA repair protein complementing XP-G cells OS=Homo sapiens GN=ERCC5 PE=1 SV=3)

HSP 1 Score: 223.016 bits (567), Expect = 2.722e-59
Identity = 121/305 (39.67%), Postives = 179/305 (58.69%), Query Frame = 0 
Query:  679 IPMEDLIGLQKDLEKEHDRLEDTTKKLKRQAATLSDETYQDVQELLRLFGIPYLVSPAEAEAQCAQLDFSKLTDGSITDDSDIFLFGGHRVYKNIFDQKKYAEVYLLDDLIKKLYLTREKLIALAFMTGSDYTEGIRGIGAVTGMEVLHEFNKNKPKETLKFFRDWLRG----KIKDFNPGSNLKNKLRDVDMSQTFNSSLVWDAYLSPTVETSEEQFEWSNPDIDALKEYASEKLGWLYNKTDELLLPVLENMKKRKERQKTLMAYFQPKVEDDIETNIKSNRLKKVLSKMSSKDYTENEAGPS 979
            I +E+L  L+ +L  + + L+   ++ +R AAT++ + + + QELLRLFGIPY+ +P EAEAQCA LD +  T G+ITDDSDI+LFG   VY+N F++ K+ E Y   D   +L L R KLI LA++ GSDYTEGI  +G VT ME+L+EF  +  +  LKF   W       KI+     + +K KLR + ++  F +  V +AYL P V+ S+  F W  PD+D ++E+     GW   KTDE L PVL+ +  ++ + +    +   + E +    IKS RL + ++ M  K   E EA  S
Sbjct:  731 INLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRK---EKEAAAS 1032

HSP 2 Score: 220.705 bits (561), Expect = 1.165e-58
Identity = 122/309 (39.48%), Postives = 193/309 (62.46%), Query Frame = 0 
Query:    1 MGVKGLWRLVASAGKPVSLESLNGKILAVDVSIWLNKAAKGMRDKRGNAIYNAHLVLMFHRICKLLFYGIKPVFVFDGGVPELKKKTLRLRRERRSQADSNRKRTKDQILKNYLQTKALEAVTGVKSTTKL-QLRDKKEKEDIFKLPEQPVQNDSSDSSSDDDV------LNEDEWLRTLNESRVQLMFDKAEKLDTSSAEFNALPAEVKHELLTEIKDYQRRRYRRKNEAEVKLPQEAGTFSDFQLGNLMKRGQITHQIDELRKEMNSSMAAQFIELYHDVDQKKYKDKHIEGKRYVSNEKQGYVLIK 302
            MGV+GLW+L+  +G+ VS E+L GKILAVD+SIWLN+A KG+RD+ GN+I N HL+ +FHR+CKLLF+ I+P+FVFDG  P LKK+TL  RR+R+  A S+ ++T +++LK +L+ +A++     K    L  L   + + D++ LP  P+Q +   SS ++D       +N+ + L+       +  F   + +D  S +F++LP EVKHE+LT++K++ +RR R   EA   +P+E+  FS +QL  L+K+  +   I+ ++KEMN   +      Y D   +    K +E +R VS +   Y+LIK
Sbjct:    1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLP--PLQEEEKHSSEEEDEKEWQERMNQKQALQ-------EEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRR-RTLFEA---MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYED---EGGFLKEVESRRVVSEDTSHYILIK 293
The following BLAST results are available for this feature:
BLAST of TCONS_00010305-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ERCC52.722e-5939.67DNA repair protein complementing XP-G cells OS=Hom... [more]
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