TCONS_00010291-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00010291-protein
Unique NameTCONS_00010291-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length767

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00010291-protein ID=TCONS_00010291-protein|Name=TCONS_00010291-protein|organism=Clytia hemisphaerica|type=polypeptide|length=767bp
MYGYFNHAFEMFITHKYGKTEWAIIRDMASVFHDHFDDELNYDENMIYEI
MDAACDHLDIDIQDLQEEFGEMYFTHCLQSEHGKFLKKLGGNLFDFFSNI
DGLHDYLNRSYADAKIPSFRVERIGDSKMTVTYFSDRDDLESIIPGIIRK
AAKMLFNLDVETTREMMPYKTIMVYTSSPETAILMFPKEPLYPRTIIPKA
NEPKVSPIEFAKICPFHIVFDDQMRFVELGAALSRILNVYSNKGERVTNY
FTITRPQVEFDFDMIKLRLNNSFVLTTITRTDEPRANKPRSNLRLKGQMI
LLEKKKMMLFLCSPNVTCIEDMTNKGLCLSDIPIHDATRDLVLLSENIQK
ELKLTQQLGIVSDHLKKIHSELHEESELYNRLLYAVLPNSIAKNLGEGNS
VRPEKFECVTLMFSGIVDFSSFCQNYDAKLIVDMLNDLYIRFDDLIRMMN
CNGDEWVYKVETIGDKYMTASGVPDRTINNPTIMCSLALDMHDASQEVTM
DGKPVEVTFGIHSGEVVAGVIGKKMPRYCLFGNSVNLASRTETTGLPGKI
NVTEYTYKLINFEDKNNPDYEKIKNFSFKKREPIKMKGKTEPMLTFTLSR
RTPRAHHHMGTRNGSTDVLSASPHNSNFFSLYRKPQHANHEYHGGSHRHH
GHSSRRKRILGKFSASSGSLIGSTNSRSRCSSWYSSFTGGPMSSLQGGSV
NNDEMSICASLRNTDLFRLQEKDQLKEDDNETEYDIDIEKDSRRESVAEQ
LLKVQRELDNSLRVQQR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005780XLOC_005780Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00010291TCONS_00010291Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001054A/G_cyclase
IPR011644Heme_NO-bd
IPR011645HNOB_dom_associated
IPR018297A/G_cyclase_CS
IPR024096NO_sig/Golgi_transp_ligand-bd
IPR029787Nucleotide_cyclase
Vocabulary: Biological Process
TermDefinition
GO:0009190cyclic nucleotide biosynthetic process
GO:0035556intracellular signal transduction
GO:0006182cGMP biosynthetic process
Vocabulary: Molecular Function
TermDefinition
GO:0016849phosphorus-oxygen lyase activity
GO:0020037heme binding
GO:0004383guanylate cyclase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006182 cGMP biosynthetic process
biological_process GO:0009190 cyclic nucleotide biosynthetic process
biological_process GO:0035556 intracellular signal transduction
molecular_function GO:0004383 guanylate cyclase activity
molecular_function GO:0020037 heme binding
molecular_function GO:0016849 phosphorus-oxygen lyase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 48..68
NoneNo IPR availableGENE3D3.90.1520.10coord: 1..171
e-value: 6.9E-45
score: 152.5
NoneNo IPR availableCDDcd07302CHDcoord: 409..598
e-value: 3.74711E-53
score: 180.853
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseSMARTSM00044cyc_6coord: 374..574
e-value: 4.2E-68
score: 242.2
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseGENE3D3.30.70.1230coord: 397..616
e-value: 1.7E-54
score: 183.8
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePFAMPF00211Guanylate_cyccoord: 403..598
e-value: 2.0E-53
score: 180.6
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePROSITEPS50125GUANYLATE_CYCLASE_2coord: 410..542
score: 36.884
IPR011644Heme-NO bindingPFAMPF07700HNOBcoord: 2..162
e-value: 3.3E-37
score: 127.8
IPR011645Haem NO binding associatedPFAMPF07701HNOBAcoord: 204..395
e-value: 8.6E-45
score: 152.8
IPR018297Adenylyl cyclase class-4/guanylyl cyclase, conserved sitePROSITEPS00452GUANYLATE_CYCLASE_1coord: 519..542
IPR024096NO signalling/Golgi transport ligand-binding domainSUPERFAMILY111126Ligand-binding domain in the NO signalling and Golgi transportcoord: 1..163
IPR029787Nucleotide cyclaseSUPERFAMILY55073Nucleotide cyclasecoord: 398..605

Blast
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BLAST of TCONS_00010291-protein vs. Swiss-Prot (Human)
Match: GCYB1 (Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens GN=GUCY1B3 PE=1 SV=1)

HSP 1 Score: 429.869 bits (1104), Expect = 1.790e-141
Identity = 243/623 (39.00%), Postives = 363/623 (58.27%), Query Frame = 0 
Query:    1 MYGYFNHAFEMFITHKYGKTEWAIIRDMASVFHD-HFDDELNYDENMIYEIMDAACDHLDIDIQDLQEEFGEMYFTHCLQSEHGKFLKKLGGNLFDFFSNIDGLHDYLNRSYADAKIPSFRVERIGDSK-MTVTYFSDRDDLESIIPGIIRKAAKMLFNLDVETTREMMPYKTIMVYTSSPE-TAILMFPKEP----LYP---RTIIPKANEPKVSPIEFAKICPFHIVFDDQMRFVELGAALSRILNVYSNKGERVTNYFTITRPQVEFDFDMIKLRLNNSFVLTTI--------TRTDEPRANKPRSNLRLKGQMILLEKKKMMLFLCSPNVTCIEDMTNKGLCLSDIPIHDATRDLVLLSENIQKELKLTQQLGIVSDHLKKIHSELHEESELYNRLLYAVLPNSIAKNLGEGNSVRPEKFECVTLMFSGIVDFSSFCQNY----DAKLIVDMLNDLYIRFDDLIRMMNCNGDEWVYKVETIGDKYMTASGVPDRTINNPTIMCSLALDMHDASQEVTMDGKPVEVTFGIHSGEVVAGVIGKKMPRYCLFGNSVNLASRTETTGLPGKINVTEYTYKLINFEDKNNPDYEKIKNFSFKKREPIKMKGKTEPMLTFTLSRR 601
            MYG+ NHA E+ +   YG   W  I+  A +  +  F   + YD++  Y+++ AA   L+++  ++ + FG+M+F  C +S +   L+ LG N+ +F  N+D LHD+L   Y   + PSFR       K + + Y+S+R+ L+ I+ GII+  A+ +   +++        K I       + T  L+  KE      Y    R       E ++SP  F K  PFHI+FD  +   + G A+ R+L         + + F++ RP ++  F  I   +N  FVL +            ++       S LRLKGQMI L +   +LFLCSP+V  ++D+T +GL LSDIP+HDATRDLVLL E  ++E KLTQ+L I++D L+     L +E +  + LLY+VLP S+A  L     V  ++++ VT++FSGIV F++FC  +     A  IV++LNDLY RFD L    +   + +VYKVET+GDKYMT SG+P+  I++   +C LALDM + + +V +DG+ V++T GIH+GEVV GVIG++MPRYCLFGN+VNL SRTETTG  GKINV+EYTY+ +   + ++P       F  + R P+ MKGK EPM  + LSR+
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDM-------KVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTL---TDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDP------QFHLEHRGPVSMKGKKEPMQVWFLSRK 607
The following BLAST results are available for this feature:
BLAST of TCONS_00010291-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GCYB11.790e-14139.00Guanylate cyclase soluble subunit beta-1 OS=Homo s... [more]
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