TCONS_00009136-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00009136-protein
Unique NameTCONS_00009136-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length932

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00009136-protein ID=TCONS_00009136-protein|Name=TCONS_00009136-protein|organism=Clytia hemisphaerica|type=polypeptide|length=932bp
MANHDSLDYDQVHRDDFDIDDGGNDELDDEKLQNLILDKAPPPERWYHGR
LGRKGAEEFLLKNNTPCAYLVRESDRKPGMYSLSYLSSTKNLSHFRITAI
CGDFYIGGRKFQSLQHLIGYYSTYGNLVKNEKLQSPVASLEPVHLAYRVV
AKFPFTGSTDTDELSFVAGDVFAVQNEIDDDWMWVVSQNDNKSGLVPKAL
TEALGPDADPFEGQSWFVAVDKHDAETILMNYGEVGNFIIRPSQNQGDYS
LCLRERTQTLRFLIKRTGQQFSLGGRSFNSIEDIISRYKKEQLAEGVSLS
RPLERVRYEPFLRNAQGSMRTREQHNGGLPRIPPPRLNSRLSDTGFVTKS
GFLIKKGNRNKWKRLYMVLKGDEQQLLYFENEKRAKPKGLFDLSYASVYT
VHDSLFGRPNCFQIVVRALNETQTHFLCTETSDQAQEWLEAIGPFCGSMN
KQNQRKISQQNAIKELRSLEITICHAQKIPVNKLPHPYCVVSLNDIKTCR
TQAKEAPEPVFDEEFKFEDLPNDITSFTVSMYTRKTGPYTKDKEMARVTV
NLNTMEPGKALDNWHSLTSAQHKSDMGSVRITAKFKHEIIMPVEEYSKLT
EVLLSRDYAFVQSLGEVSKDLNSLAFTLLKIFRQSSQDEHEEIQLIKTIT
SRELNNREKKETLFRGNTLATKLMDQYMKMVAIPYLQKTIKSVILKIMES
RQNCELNPSRIEKGSNVAENLQQLIKFLEEITSNVFNSKQDCPKHLRYLF
YCLQTEAKSVWPDEPEIPSRVVSAFLFLRLIVPAVLNPKMHNLVGESPSP
MASRTLTLVAMCLQKLANLVEFGAKEPYLVVVNPFLKKYRSKMIDFLDDI
SNYSHPPSKMTEQNINKPDNTSRDLARDLASIHETCIKHDPQLQKLSSNQ
AHVKILLAIVEGVKQRKEQYISQSTQCDEFSI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005120XLOC_005120Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00009136TCONS_00009136Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000980SH2
IPR001452SH3_domain
IPR001936RasGAP_dom
IPR001849PH_domain
IPR000008C2_dom
IPR011993PH_dom-like
IPR008936Rho_GTPase_activation_prot
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
Vocabulary: Biological Process
TermDefinition
GO:0043087regulation of GTPase activity
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0043087 regulation of GTPase activity
biological_process GO:0007165 signal transduction
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 711..731
NoneNo IPR availableGENE3D1.10.506.10coord: 643..852
e-value: 7.0E-58
score: 195.2
NoneNo IPR availableGENE3D2.30.30.40coord: 147..201
e-value: 2.2E-11
score: 42.6
NoneNo IPR availableCDDcd13260PH_RASA1coord: 347..446
e-value: 3.42341E-50
score: 171.759
IPR000980SH2 domainPRINTSPR00401SH2DOMAINcoord: 46..60
score: 46.34
coord: 110..124
score: 37.04
coord: 66..76
score: 41.08
coord: 78..89
score: 35.39
IPR000980SH2 domainSMARTSM00252SH2_5coord: 214..294
e-value: 1.4E-19
score: 81.1
coord: 44..127
e-value: 8.4E-22
score: 88.4
IPR000980SH2 domainPFAMPF00017SH2coord: 219..288
e-value: 6.0E-11
score: 42.2
coord: 46..121
e-value: 1.5E-16
score: 60.1
IPR000980SH2 domainGENE3D3.30.505.10coord: 39..146
e-value: 5.8E-22
score: 77.6
IPR000980SH2 domainGENE3D3.30.505.10coord: 202..310
e-value: 9.9E-19
score: 66.6
IPR000980SH2 domainPROSITEPS50001SH2coord: 210..303
score: 14.319
IPR000980SH2 domainPROSITEPS50001SH2coord: 46..137
score: 19.273
IPR000980SH2 domainSUPERFAMILY55550SH2 domaincoord: 44..125
IPR000980SH2 domainSUPERFAMILY55550SH2 domaincoord: 210..305
IPR001452SH3 domainSMARTSM00326SH3_2coord: 147..205
e-value: 2.0E-11
score: 53.9
IPR001452SH3 domainPFAMPF00018SH3_1coord: 150..198
e-value: 1.1E-8
score: 34.5
IPR001452SH3 domainPROSITEPS50002SH3coord: 144..206
score: 11.665
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 140..210
IPR001936Ras GTPase-activating proteinSMARTSM00323RasGAP_2coord: 571..924
e-value: 3.9E-85
score: 298.8
IPR001936Ras GTPase-activating proteinPFAMPF00616RasGAPcoord: 717..818
e-value: 1.9E-16
score: 60.3
coord: 645..713
e-value: 3.3E-11
score: 43.2
IPR001936Ras GTPase-activating proteinPROSITEPS50018RAS_GTPASE_ACTIV_2coord: 620..818
score: 44.557
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 347..449
e-value: 3.1E-19
score: 79.9
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 347..442
e-value: 5.1E-19
score: 68.6
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 346..447
score: 14.278
IPR000008C2 domainSMARTSM00239C2_3ccoord: 468..564
e-value: 1.7E-8
score: 44.2
IPR000008C2 domainPFAMPF00168C2coord: 468..567
e-value: 9.0E-11
score: 41.9
IPR000008C2 domainGENE3D2.60.40.150coord: 471..590
e-value: 8.2E-16
score: 57.7
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 469..602
IPR011993PH domain-likeGENE3D2.30.29.30coord: 338..470
e-value: 3.3E-22
score: 78.0
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 325..442
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 591..908

Blast
[Close]
BLAST of TCONS_00009136-protein vs. Swiss-Prot (Human)
Match: RASA1 (Ras GTPase-activating protein 1 OS=Homo sapiens GN=RASA1 PE=1 SV=1)

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 397/924 (42.97%), Postives = 563/924 (60.93%), Query Frame = 0 
Query:   19 IDDGGNDELDD---EKLQNLILDKAPPPERWYHGRLGRKGAEEFLLKNNTPCAYLVRESDRKPGMYSLSYLSSTKNLSHFRITAICGDFYIGGRKFQSLQHLIGYYSTYGNLVKNEKLQSPVASLEPVHLAYRVVAKFPFTGSTDTDELSFVAGDVFAVQNEIDDDWMWVVSQNDNKSGLVPKALTEALGPDADPFEGQSWFVA-VDKHDAETILMNYGEVGNFIIRPSQNQ-GDYSLCLRERTQTLRFLIKRT-GQQFSLGGRSFNSIEDIISRYKKEQLAEGVSLSRPLERVRYEPFLRNAQGSMRTREQHNGGLPRIPPPRLNSRLSDTGF--VTKSGFLIKKGNRNKWKRLYMVLKGDEQQLLYFENEKRA-KPKGLFDLSYASVYTVHDSLFGRPNCFQIVVRALNETQTHF-LCTETSDQAQEWLEAIGPFCGSMNKQNQRKISQQNAIKELRSLEITICH---AQKIPVNKLPHPYCVVSLNDIKTCRTQAKEAPEPVFDEEFKFEDLPNDITSFTVSMYTRKTGPYTKDKEMARVTVNLNTMEPGKALDNWHSLTSAQHKSDM--GSVRITAKFKHEIIMPVEEYSKLTEVLLSRDYAFVQSLGEV-SKDLNSLAFTLLKIFRQSSQDEHEEIQ--LIKTITSRELNNREKKETLFRGNTLATKLMDQYMKMVAIPYLQKTIKSVILKIMESRQNCELNPSRIEKGSNVAENLQQLIKFLEEITSNVFNSKQDCPKHLRYLFYCLQTEAKSVWPDEPEIPSRVVSAFLFLRLIVPAVLNPKMHNLVGESPSPMASRTLTLVAMCLQKLANLVEFGAKEPYLVVVNPFLKKYRSKMIDFLDDISNYSHPPSKMTEQNINKPDNTSRDLARDLASIHETCIKHDPQLQKLSSN---QAHV-KILLAIVEGVKQRKEQY 920
            +D+G  D LD    E+ +  I   APP  +WYHG+L R  AEE L +     +YL+RESDR+PG + LS+LS    ++HFRI A+CGD+YIGGR+F SL  LIGYYS    L+K EKL  PVA  EPV    RV A  P+T   DTDE+SF+ GD+F V NE++D WMWV +   ++ GL+ + L E +G + DP EG+ WF   + K +A  +LM  G+V +F++RPS N  GDYSL  R      RF I  T   QF +GGR +NSI DII  Y+KEQ+ EG  L  P+     E  L +   ++  +E +N          +  +  D  +  + K G+L+KKG   +WK LY +L+G + QL+YFE+EKRA KPKGL DLS  SVY VHDSLFGRPNCFQIVV+  +E    F    ET +QA++W++ +  FC      N RK S   + K LR +   + H   A K+PV    +PYC + LN ++  +T A+E   PV+ EEF F+DLP DI  F +++  +     +KD ++  +   L+ ++ G A D W  L+S      +  GS+R+ A++  E IMP EEYS+  E++L ++   V +L  V  +D   LA  LL+IF       HE+++  L+ T+  RE++  ++  TLFR  TLA+ LM+QYMK  A  ++   +K  ILKIMES+Q+CEL+PS++EK  +V  NL  L+  L E+   +F + +  P  LRY++ CLQ   +  WP    + +RVVS F+FLRLI PA+LNP+M N++ +SPSP+A+RTL LVA  +Q LANLVEFGAKEPY+  VNPF+K  + +MI FLD++ N    P        +  +++  DL+RDLA++HE C+ H  +L+ LS+    Q HV K LLAI E ++Q++ QY
Sbjct:  153 VDEG--DSLDGPEYEEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLND---TVDGKEIYN---------TIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFC------NLRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKK--SKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFL------HEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELP--------DTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQY 1040
The following BLAST results are available for this feature:
BLAST of TCONS_00009136-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RASA10.000e+042.97Ras GTPase-activating protein 1 OS=Homo sapiens GN... [more]
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