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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00007957-protein ID=TCONS_00007957-protein|Name=TCONS_00007957-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1378bp
MKRFRNAVERTHDAIEAEKREMLSSDTDSDGEGTVVRRRKGGRRNQANRN
SHFLEDTFGSDEVHIWLDLFINFPSLQNVSGLHIKLEQADGEWMARFLEQ
HGLEAVLNMLYSLSYLRFNRADNKEKIDLDDAIIMLASINCLRAVMRNNK
GLQYFCDGCDPDVTKNVLLTLDTGNVMVKKQVFEMLSGVCLYSERGYQLA
LSALENFKTEKSQRYRFSIILNELKNAELFAYKTTLLAFINAILMSTVDF
NERRQIRNEFIGLGLLDELTALRHENDEDFLTQIVVFDEQKQQDDDMMIT
GDGLDLNDHQQVFRAVFDQIANKPIANNFLRILQSLLMIDVESEYSDRVW
EIIEDIVVRAVYITNEKQELAGKRRAEQELKKISNAFERTQTVAIQTDLL
KEKKKPVTMVKETQTDAVPKKLPSGAVALPGIANPGASPAPVAAPPPPPP
PPPPPPPGMGAPPPPPPPPPPPGGMMPPPPPPGMGVPPPPPPPGMGGPPP
PPPPPPPPGMAGVPPPPPPPGMGVPPPPPPPGMGGPPPPPPPPPPPGMAG
VPPPPPPPGMGVPPPPPPPPGMGGVPPPPPPPGMGGVPPPPPPPGMGAPP
PPPMFGGVPPPPPPGFAQTVPDGPTSKIKPTRTPSSKMKKLQWNKIPTHV
LKRNSSSVWNKVIEVDGVEPDYLIEEDLFKQAEKKKVEKVEKPKEPKEIS
LLDPKRSMNINIFLKQFKGGPAQLIEWIRIGNATDIGGDRLKCLETLLPD
SSEKETIKSFSGDRNKLGPAEKFVELMCELPSYEFRIKGLILKEDFLVNK
ESLQPQIEVFKGAVEDILNNETLPEILNLILRVGNFMNHGSHAGNAEAFK
FNSLLKLTDTRANKPRMNLMHFIVQVAVDKKEALLEFPKSMTHLDASVRL
SIDNLEKEVVTLKRSLEAAQKQLDKVSEDVQEQMGEFLGQSIIEITVLEV
QCKEIRKLVAEMANYFCEEPKKFVVEEYLNMMKQFCEKLTKAKDENEQFK
KQEKRRIEREKKEAEEKARREKLGIKEKPKGRRAPPPMEEKSIIDNLLDE
IKNGFPLKKSQVTSPTKKEAPSTKENVDPKKARRNWKKTKALASLIVTGK
QKSVEEENRKNKELSMLNSDSDSSSNGLSNGKISNGEISNGHSTAIKTND
DEHLSNGTSKSSDVKDEKVPTEPIDEVDNTSGKTTIFRESSIKPKRASVS
SRTSVSSRASVSSRKSNSDVNDAIASLDDIEITEAAATKKEVTVTEAEKP
SEIMRVSSPRRKKFSLDNNKVVSNNDVKLDKKQNEGVDVESSYESCSAEQ
AQPSQSMPNLSNDSVEEAVELDQATPRNAVSEGGLNTPKSPKPDREKPKL
TTKANQMIQCRKRRRSGEYTMIAILERK Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0003779 | actin binding |
| GO:0017048 | Rho GTPase binding |
| GO:0005488 | binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0016043 | cellular component organization |
| GO:0030036 | actin cytoskeleton organization |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0030036 |
actin cytoskeleton organization |
| biological_process |
GO:0016043 |
cellular component organization |
| molecular_function |
GO:0003779 |
actin binding |
| molecular_function |
GO:0005488 |
binding |
| molecular_function |
GO:0017048 |
Rho GTPase binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 1..21 |
| None | No IPR available | COILS | Coil | Coil | coord: 975..1024 |
| None | No IPR available | COILS | Coil | Coil | coord: 902..936 |
| None | No IPR available | COILS | Coil | Coil | coord: 373..393 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1240..1355 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 996..1040 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1055..1220 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 21..48 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 421..639 |
| None | No IPR available | SUPERFAMILY | 101447 | Formin homology 2 domain (FH2 domain) | coord: 641..1009 |
| IPR015425 | Formin, FH2 domain | SMART | SM00498 | it6_source | coord: 412..1069
e-value: 6.8E-64
score: 228.2 |
| IPR015425 | Formin, FH2 domain | PFAM | PF02181 | FH2 | coord: 629..989
e-value: 1.3E-76
score: 258.0 |
| IPR015425 | Formin, FH2 domain | PROSITE | PS51444 | FH2 | coord: 628..1015
score: 59.693 |
| IPR010472 | Formin, FH3 domain | SMART | SM01139 | Drf_FH3_2 | coord: 195..642
e-value: 3.9E-49
score: 179.2 |
| IPR010472 | Formin, FH3 domain | PFAM | PF06367 | Drf_FH3 | coord: 196..366
e-value: 3.0E-23
score: 82.4 |
| IPR010473 | Formin, GTPase-binding domain | SMART | SM01140 | Drf_GBD_2 | coord: 8..191
e-value: 8.2E-9
score: 45.3 |
| IPR010473 | Formin, GTPase-binding domain | PFAM | PF06371 | Drf_GBD | coord: 18..191
e-value: 5.1E-9
score: 35.9 |
| IPR011989 | Armadillo-like helical | GENE3D | 1.25.10.10 | | coord: 72..298
e-value: 1.3E-46
score: 158.1 |
| IPR014768 | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain | PROSITE | PS51232 | GBD_FH3 | coord: 1..368
score: 18.004 |
| IPR016024 | Armadillo-type fold | SUPERFAMILY | 48371 | ARM repeat | coord: 74..368 |
Blast
BLAST of TCONS_00007957-protein vs. Swiss-Prot (Human)
Match: FHDC1 (FH2 domain-containing protein 1 OS=Homo sapiens GN=FHDC1 PE=1 SV=2) HSP 1 Score: 250.366 bits (638), Expect = 8.502e-68 Identity = 143/403 (35.48%), Postives = 226/403 (56.08%), Query Frame = 0
Query: 637 KMKKLQWNKIPTHVLKRNSSSVWNKVIEVDGVEPDYLIE----EDLFKQAEKKKVEKVEKPKEPK-----------EISLLDPKRSMNINIFLKQFKGGPAQLIEWIRIGNATDIGGDRLKCLETLLPDSSEKETIKSFSGDRNKLGPAEKFVELMCELPSYEFRIKGLILKEDFLVNKESLQPQIEVFKGAVEDILNNETLPEILNLILRVGNFMNHGSHAGNAEAFKFNSLLKLTDTRANKPRMNLMHFIVQVAVDKKEALLEFPKSMTHLDASVRLSIDNLEKEVVTLKRSLEAAQKQLDKVSEDVQEQMGEFLGQSIIEITVLEVQCKEIRKLVAEMANYFCEEPKKFVVEEYLNMMKQFCEKLTKAKDENEQFKKQEKRRIEREKKEAEEKARREKLG 1024
+M+ W IP + R +++W E Y I+ E+LF Q E K P+ + EI++LD KRSMNI IFLKQFK P ++E I G + G + L+ LP+S E + +K+FSGD +KL A+ F+ + ++P+Y RI+ ++LK++FL + SL I V + A++++++ E L IL+L+L+ GN MN G +AGNA FK +SLLKL DT+ANKP MNL+HF+ Q A K LL F + + H+ + RLS++N E E+ L ++ ++ + + E Q QM +FL +I ++ LE +E++ + ++FCE+ K ++E + + FC K KA +N + QE R+++R KE E+K R G
Sbjct: 96 RMRSFFWKTIPEEQV-RGKTNIWTLAARQ---EHHYQIDTKTIEELFGQQED--TTKSSLPRRGRTLNSSFREAREEITILDAKRSMNIGIFLKQFKKSPRSIVEDIHQGKSEHYGSETLREFLKFLPESEEVKKLKAFSGDVSKLSLADSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQRDGELCQ-QMEDFLQFAIEKLRELECWKQELQDEAYTLIDFFCEDKKTMKLDECFQIFRDFCTKFNKAVKDNHDREAQELRQLQR-LKEQEQKQRSWATG 490
The following BLAST results are available for this feature:
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