TCONS_00007497-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00007497-protein
Unique NameTCONS_00007497-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length777

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00007497-protein ID=TCONS_00007497-protein|Name=TCONS_00007497-protein|organism=Clytia hemisphaerica|type=polypeptide|length=777bp
MFIFILHAFIIVTSQTKWTWTTSITVNDDDVIKTLNRDISKNKNDAAIRN
NINVRDFEILRTDQFIHVKNGVTTRQVTFDFHNRQFVLELRQNSDILTDD
FDIRHHATIDRRELYTGYVKGEFTSDVHVAIDNNDVITGVVYTDAITLRI
EPLRGYATNARKREMIIYAHSNDVTRFSGKKIGDDDFALMLGKGLKEEGR
LKNARKTEQITRKAEENARKTGENTYEFLQDISQKPLFRTRRSNTNKCDF
PKKTLCPMYVVADHRFFKYVGGSEKKNTIYHMLQAIRFADKVFKETTWND
GVTCNIGLTVGDFYVLEKPGNFSFNKPADDNKPEAYQNILQDFSREKSLL
PGWKSSYCLAHLFTYRDFKDDVVGYAYIGNEDTSPGRYNHGSHAKSYGIC
GQQNVAFSSYFNSARNTGLLTLEANLVTTHEIAHNFGARHDKKKDPTCYL
GRESDTGNFLMFDLMVTGRKRNNAKLSPCSIASISRVIKRKSERCFIQQN
DTLCTNGVLDPGEECDPGLFGNDDPCCDRNCNLKPGAQCSDLNHVCCTEC
QFASGKLCKERSDADCLEASYCDGTSAGCVNITRDPITDNTTCDYGKGNC
QKEGCVSICNQRGKEECNCADAGIDACKICCRDKQTGLCSQVLDSEHVWD
GVPCEVNNKIGTCRAGICVKVKRRVDDEFDALLKDFSFNNLRLFMMKNIV
GTILVISILFWAPVACVVHWLDKKQDEEEKFNLNWTLPSNSELVLSRGAR
KKRLGLLFRRQAASAKRVKGGQFHISR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004229XLOC_004229Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00007497TCONS_00007497Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001762Disintegrin_dom
IPR002870Peptidase_M12B_N
IPR024079MetalloPept_cat_dom
IPR001590Peptidase_M12B
Vocabulary: Molecular Function
TermDefinition
GO:0008237metallopeptidase activity
GO:0004222metalloendopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001762Disintegrin domainSMARTSM00050DISIN_2coord: 510..584
e-value: 8.6E-12
score: 55.2
IPR001762Disintegrin domainGENE3D4.10.70.10coord: 508..582
e-value: 1.8E-13
score: 50.5
IPR001762Disintegrin domainPFAMPF00200Disintegrincoord: 510..580
e-value: 1.1E-12
score: 48.5
IPR001762Disintegrin domainPROSITEPS50214DISINTEGRIN_2coord: 501..590
score: 12.511
IPR001762Disintegrin domainSUPERFAMILY57552Blood coagulation inhibitor (disintegrin)coord: 510..580
NoneNo IPR availablePFAMPF13688Reprolysin_5coord: 254..462
e-value: 1.7E-21
score: 77.2
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 252..497
IPR002870Peptidase M12B, propeptidePFAMPF01562Pep_M12B_propepcoord: 72..168
e-value: 1.1E-7
score: 32.0
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 250..500
e-value: 2.7E-38
score: 131.4
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 254..500
score: 18.528

Blast
[Close]
BLAST of TCONS_00007497-protein vs. Swiss-Prot (Human)
Match: ADA17 (Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1)

HSP 1 Score: 322.013 bits (824), Expect = 5.363e-98
Identity = 226/712 (31.74%), Postives = 351/712 (49.30%), Query Frame = 0 
Query:   77 VTFDFHNRQFVLELRQNSDILTDDFDI-------RHHATIDRRELYTGYVKGEFTSDVHVAIDNNDVITGVVYTDAITLRIEPLRGYATNARKREMIIYAHSN--DVTRFSGKKIG---DDDFALMLGKGLKEEGRLKNARKTEQITRKAEENARKTGENTYEFLQDISQKPLFRTRRSNTNKCDFPKKTLCPMYVVADHRFFKYVGGSEKKNTIYHMLQAIRFADKVFKETTWNDGVTCNIGLTVGDFYVLEKPGNFSFNKPADD--NKPEAYQNILQDFSREKSLLPGWK-------SSYCLAHLFTYRDFKDDVVGYAYIGNEDTSPGRYNHGS--HAKSYGICGQQNVAFSSYFNSARNTG--LLTLEANLVTTHEIAHNFGARHDKKKDPTCYLGRESDTGNFLMFDLMVTGRKRNNAKLSPCSIASISRVIKRKSERCFIQQNDTLCTNGVLDPGEECDPG-LFGNDDPCCDRNCNLKPGAQCSDLNHVCCTECQFASG-KLCKERSDADCLEASYCDGTSAGCVNITRDPITDNTTC-DYGKGNCQKEGCVSICNQRGK-EECNCADAGIDACKICCRDKQTGLCSQVLDSEH----VWDGVPCEVNNKIGTCRA-GICVKVKRRVDDEFDALLKDFSFNNLRLFMMKNIVGTILVISILFWAPVACVVHWLDKKQDEEEKFNLNWTLPSNSELVLSRGARKKRL 754
            +TF    R F L L  +++  + +F +           T+  ++ +TG+V GE  S V   I ++DVI  +  TD     IEPL  +  + + + M++Y   +  +V+R    K+      D   +L KGL +  R        ++ R+A+ +                                 P K  C + VVADHRF++Y+G  E+  T  ++++ I   D +++ T+W++      G+ +    +L+ P      KP +   N  ++Y N  +D    K LL  +        S  CLAHLFTY+DF    +G AY+G    SP   +HG       Y   G++N+  +S   S +N G  +LT EA+LVTTHE+ HNFGA HD      C    E   G ++M+ + V+G   NN   S CS  SI + I+ K++ CF ++++ +C N  +D GEECDPG ++ N+D CC+ +C LK G QCSD N  CC  CQF +  K C+E  +A C   SYC G S+ C         D+T C D GK  C+   C+  C +  + E C C +   ++CK+CCRD  +G C   +D+E     +  G PC V    G C   G C K  + V + F   +   S N    F+  NIVG++LV S++FW P + +VH +DKK D++ + +L+   PSN E++ S  +   R+
Sbjct:   70 LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRI-NTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVD--REPPEELVHRVKRRADPD---------------------------------PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEV---KPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVG----SPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAEC-APNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGN--AEDDTVCLDLGK--CKDGKCIPFCEREQQLESCACNETD-NSCKVCCRD-LSGRCVPYVDAEQKNLFLRKGKPCTV----GFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYE-SLSLFHPSNVEMLSSMDSASVRI 726
The following BLAST results are available for this feature:
BLAST of TCONS_00007497-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ADA175.363e-9831.74Disintegrin and metalloproteinase domain-containin... [more]
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