Ras guanine nucleotide exchange factor protein (polypeptide) - C. hemisphaerica

Overview
NameRas guanine nucleotide exchange factor protein
Unique NameTCONS_00006266-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1071

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006266-protein ID=TCONS_00006266-protein|Name=Ras guanine nucleotide exchange factor protein|organism=Clytia hemisphaerica|type=polypeptide|length=1071bp
MNKMTFQRSEHINIPRKVNSILKYGSSYNGHQSDDSDSDDDEQIRRKFIN
LNSGRGMIISSNTFTPHLDLNKSAGHQDQGYYENVMFHNENQLSRKSRSL
KYRHGGIPVPPIDLDNIQMNNECEYGFNPNRLSGSKADYRLKLRPLSVYS
PKPQKIPLKYSNSDADERYSTVSPRRPISHASNDLEYDLEQELATIRSQP
SNIKFQGCKGKVNQKEFLEDLASSRKYRKIRRQLSFDSHPTRKWQKTVSL
DSGLASSSFKRSKSNDSISEKEGKSQSQTLLDIDEGESMRPGLKRLSFSA
EYIIDDITPASTPDEDDNKTLEKTTENLDESISEEEAQPDEVRIVPKFVE
ELPPTEDLLLSNSSKSYTVNKSNEKQKRRNIPHILNAFRIPNKKLKKLMK
KRPSDSHNSPLKATHDFNEDVTLIETQALDNQESSSENTTPRVKVSMGTD
NESFDDSVNTFTKHDELNDSTDFGELKSSCSLPKVDEDKESLEFTISKSP
FDHRRSKSSCNITTVNTAESTPQKDEKRQSRRMSDTILSDKPAPHHTHSP
SKRFIRKIFSPMVCGVPSPDRRXSPSKRFIRKIFSPMVCGVPSPDRRHLF
TNNGSLLSLGSYDSASVISDHEQDAYPQLFDFGSHELMEEMTLIDKELLV
RIPWGELSILGWMSTDKYIIAPNIMKMVEFFNRVVMMVTTSILSEENVYR
RAKIIQKAIKLALKFRYQKNFNSLKAVLGGLQCTPIFRLKQTWKQVPSRY
RRVFRELSELMSEENNFYNYRMVLRESMEKPPCIPFLGNFLTTVAHTHAF
VSVNYKYKKDSAIESGGESDSNRTSPSPTSSPHEGEDESSNKNSELDKQI
DPCLRSSTSKIHSASHMRTDSDDSGVVLNVHRLSRSSDDLETSPREESLS
SPDDDGRVRFHEEVFDKKNSQQEDEECFCPSNQETEKAKKPRFSDTDLPS
TTTTSSTPNPTRTQLSVCPRHRRSVSEIIMSPTRHHSRSISDAGIRNAND
INNVINNRPVAGKENSGLYTCELQFWKYQINAVQYKIIPKSYIRRYLMNC
PYNTEEENYKLSLKREPPAPR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003580XLOC_003580Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006266TCONS_00006266Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001895RASGEF_cat_dom
IPR023578Ras_GEF_dom
Vocabulary: Biological Process
TermDefinition
GO:0007264small GTPase mediated signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005085guanyl-nucleotide exchange factor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007264 small GTPase mediated signal transduction
molecular_function GO:0005085 guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 318..338
IPR001895Ras guanine-nucleotide exchange factors catalytic domainSMARTSM00147RasGEF_3coord: 629..1069
e-value: 1.3E-43
score: 160.8
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPFAMPF00617RasGEFcoord: 638..798
e-value: 1.1E-44
score: 152.7
IPR001895Ras guanine-nucleotide exchange factors catalytic domainGENE3D1.10.840.10coord: 621..1071
e-value: 9.6E-69
score: 231.2
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPROSITEPS50009RASGEF_CATcoord: 633..890
score: 40.886
IPR023578Ras guanine nucleotide exchange factor domainSUPERFAMILY48366Ras GEFcoord: 621..800

Blast
[Close]
BLAST of Ras guanine nucleotide exchange factor protein vs. Swiss-Prot (Human)
Match: RGRF1 (Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens GN=RASGRF1 PE=1 SV=2)

HSP 1 Score: 102.834 bits (255), Expect = 5.109e-22
Identity = 52/160 (32.50%), Postives = 90/160 (56.25%), Query Frame = 0 
Query:  636 ELMEEMTLIDKELLVRIPWGELSILGWMSTDKYIIAPNIMKMVEFFNRVVMMVTTSILSEENVYRRAKIIQKAIKLALKFRYQKNFNSLKAVLGGLQCTPIFRLKQTWKQVPSRYRRVFRELSELMSEENNFYNYRMVLRESMEKPPCIPFLGNFLTTVA 795
            E+ E++TL+D  +  +IP+ E    GWM  +K    P IMK  + FN +  ++ + I+  E++  R   I+K + +A   R   N+N++  +   +  + IFRLK+TW +V  + + +  +L +L+S E  F N R  L+     PPC+P+LG +LT +A
Sbjct: 1041 EIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNC--DPPCVPYLGMYLTDLA 1198
The following BLAST results are available for this feature:
BLAST of Ras guanine nucleotide exchange factor protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RGRF15.109e-2232.50Ras-specific guanine nucleotide-releasing factor 1... [more]
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