TCONS_00006064-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00006064-protein
Unique NameTCONS_00006064-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length732

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006064-protein ID=TCONS_00006064-protein|Name=TCONS_00006064-protein|organism=Clytia hemisphaerica|type=polypeptide|length=732bp
MKWMSIKELMLFFLLMLFYVEFVASTDESSTQLNQTQREDLKKIVHPYAE
DHAIIDDITHYNQLVAEHTDKEFVSLYRDDDNMAKLTEGDILPDPKDQRK
LNTTSKQTNATTVRRGMLSDSTQLWISRVIPYEIHHPGTFLGQSTADVIR
EVKKAFETITNAAPCLKFRPRSSSDKNWLSIQKKAGCYSEFGRKYWLRKE
TVLVLGDGCVNQPIILHEILHALGFYHEQARPDRDSYVKINWENINEKFK
SNFDRQTAYSLDSQSTAYNTKSIMHYGHRTFSKNGQDTIIDKFDPNNIDL
AGDVLSYSDRAELTKKYQCYKDDTDIWSAWADWTSCFEHFVFGCRKERQR
FCFVFDSQPEKCKEGNEFGIQAETEKCDEKMCKEEVLAPHWGRWSHYTRC
SRDCGEGYHLRSRECDNPPPAKDSGDRCRGIKYETSLCRNKRCSPDYFRY
DVDFESGFEPWRMDVKGLNIIPWRISDRGTPNEKTGPEKPFITKHYAFLS
GKFEDSNVKYKDGRLISEPIFEFNQTHCVTFYYQLNGRDIKHMDLYIRLI
KSGGFKNFWSLKGHQGNSWKRGAFTIDEQKEPYEIIVEGRIGRNPPSDIA
IDDIRVEKGSCVKGSNEGSEGCRNHYKMCKWWKQYGECHKNFRWMLKSCC
LSCTSMAYCFDIYDYRNKTTKCEEWVKKGECRRNPKWMWKNCCKSCRKCV
DYRPSCKYWAKKYCDHPWMKKNCQTSCNICKI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003452XLOC_003452Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006064TCONS_00006064Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001506Peptidase_M12A
IPR000998MAM_dom
IPR000884TSP1_rpt
IPR006026Peptidase_Metallo
IPR003582ShKT_dom
IPR024079MetalloPept_cat_dom
IPR034035Astacin-like_dom
IPR013320ConA-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016020 membrane
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001506Peptidase M12APRINTSPR00480ASTACINcoord: 228..245
score: 56.39
coord: 305..318
score: 29.88
coord: 209..227
score: 49.47
coord: 267..282
score: 47.08
IPR001506Peptidase M12APFAMPF01400Astacincoord: 124..320
e-value: 1.8E-45
score: 154.8
IPR000998MAM domainSMARTSM00137MAM_2coord: 447..613
e-value: 5.6E-16
score: 69.1
IPR000998MAM domainPFAMPF00629MAMcoord: 453..611
e-value: 1.1E-23
score: 83.8
IPR000998MAM domainPROSITEPS50060MAM_2coord: 450..613
score: 21.706
IPR000998MAM domainCDDcd06263MAMcoord: 473..611
e-value: 1.25454E-23
score: 97.4485
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 327..383
e-value: 0.41
score: 12.8
coord: 391..444
e-value: 3.1E-7
score: 40.1
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 393..443
e-value: 3.2E-6
score: 27.1
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 388..443
e-value: 1.6E-9
score: 37.5
coord: 325..382
e-value: 0.17
score: 11.7
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 388..444
score: 11.144
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 388..443
IPR006026Peptidase, metallopeptidaseSMARTSM00235col_5coord: 121..272
e-value: 9.0E-28
score: 108.3
IPR003582ShKT domainSMARTSM00254ShkT_1coord: 658..697
e-value: 20.0
score: 6.7
coord: 621..654
e-value: 18.0
score: 7.3
coord: 698..731
e-value: 2.0E-6
score: 37.3
IPR003582ShKT domainPFAMPF01549ShKcoord: 698..730
e-value: 2.7E-5
score: 24.5
coord: 621..653
e-value: 0.091
score: 13.2
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 622..659
score: 8.43
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 699..730
score: 10.547
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 663..698
score: 7.793
NoneNo IPR availableGENE3D2.60.120.200coord: 447..613
e-value: 2.2E-27
score: 95.5
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 119..318
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 116..321
e-value: 4.4E-43
score: 147.0
IPR034035Astacin-like metallopeptidase domainCDDcd04280ZnMc_astacin_likecoord: 127..317
e-value: 2.65742E-55
score: 187.008
IPR013320Concanavalin A-like lectin/glucanase domainSUPERFAMILY49899Concanavalin A-like lectins/glucanasescoord: 448..611

Blast
[Close]
BLAST of TCONS_00006064-protein vs. Swiss-Prot (Human)
Match: MEP1A (Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE=1 SV=2)

HSP 1 Score: 99.7525 bits (247), Expect = 1.377e-21
Identity = 58/162 (35.80%), Postives = 86/162 (53.09%), Query Frame = 0 
Query:  165 CLKFRPRSSSDKNWLSIQKKAGCYSEFGRKYWLRKETVLVLGDGCVNQPIILHEILHALGFYHEQARPDRDSYVKINWENINEKFKSNFDRQTAYSLDSQSTAYNTKSIMHYGHRTFSKNGQDTIIDKFDPNNIDLAGDVLSYS--DRAELTKKYQCYKDDT 324
            C+ F+P    + +++  Q+  GC+SE G ++  +    + +G GC  + II HEILHALGFYHEQ+R DRD YV I W+ I   ++ NFD      +   +T Y+ +S+MHY   +F+KN     I    P    + G  L +S  D   L + Y C    T
Sbjct:  107 CVDFKPYEG-ESSYIIFQQFDGCWSEVGDQHVGQN---ISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHT 264
The following BLAST results are available for this feature:
BLAST of TCONS_00006064-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MEP1A1.377e-2135.80Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE... [more]
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