TCONS_00004551-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004551-protein
Unique NameTCONS_00004551-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length834

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004551-protein ID=TCONS_00004551-protein|Name=TCONS_00004551-protein|organism=Clytia hemisphaerica|type=polypeptide|length=834bp
MFITSIFLVALFSNANALTVQLSKSSAVAAVDSTLLVDCVTNPTDGVNVY
WEKGGEAVPLQPTSGKEPEFFYMSNNTLKITKVKRRHAGTYSCFAKHKTE
FRFAEFKVEIMYIQQANPLEPRKTYSGVEVEMQCIPPLGKPNPKPLWLKD
GKTFSDPRVDQSTFTLKISKTQLSDTANYTCVSMGYKNRTTTASLTVYEK
GPFSVKPEKINATEGDKVEFKCISGTKPPLPLKWFKRNKQCDDKGCKTLD
EDVDLMSDVRFVKTDDGVLTITKVKPEDKADYVCTRFLGATTEEAVVKLH
VITLIKIDLKPKASIDIDSTKPHTVACPYQGVNPKSISWIRKDTGALPSH
MNVDGSTLVITKPQLSDSGVYTCKIVGPLNSDEATVNLTMYKGLKFIKRP
SNITGVVSKPLWIDCVGSGYPEPWVFYFRIGKGGGELNSTYFTTHKNGTL
YIPKLRKEDQGKYMCILKNDPGGSKTSQFELTVKSENEKAGASSPMHRTI
GIAVGCAGVYILLVIGLMIYCRARRARLLKGIITEVDGEGKDPLIGNGNK
DIPLDDMKKFSQWEYKRSGLEEIGTLGHGKMGRVYKANAVDIRPSEKRTL
VAVKEFNSDEKEHKDEFNIEMEMFTQLDHINVVKLLGVCMNASPPDPWLL
ITDFGEEGDLKGYLDRNKNLSIHERLDMSMCVANGMDYLIAQHYMHRDLA
ARNCVVRANKSVSISFLSLCEDTYKDDYFSLNDYPVPLRWLSPECIQEEN
YSEKSDVWSFGITVWEIFSNGDRPYANFDNDAVLKGVCLDLRLTKPKDCP
DSIFHIMESCWLKEASERPSFADLKSAINDVKID
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002559XLOC_002559Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004551TCONS_00004551Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR003599Ig_sub
IPR003598Ig_sub2
IPR013783Ig-like_fold
IPR013098Ig_I-set
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 755..777
score: 56.27
coord: 736..746
score: 42.55
coord: 652..665
score: 31.08
coord: 688..706
score: 58.04
coord: 799..821
score: 41.24
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 574..826
e-value: 2.2E-74
score: 249.9
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 570..828
e-value: 1.3E-77
score: 273.9
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 207..302
e-value: 5.8E-8
score: 42.5
coord: 312..391
e-value: 0.0013
score: 28.0
coord: 119..198
e-value: 1.2E-4
score: 31.5
coord: 400..484
e-value: 9.5E-9
score: 45.1
coord: 24..109
e-value: 1.1E-4
score: 31.6
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 318..380
e-value: 0.02
score: 23.5
coord: 30..100
e-value: 2.9E-7
score: 40.1
coord: 406..472
e-value: 0.0095
score: 25.1
coord: 125..188
e-value: 0.25
score: 12.8
coord: 213..291
e-value: 0.0041
score: 26.4
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 306..383
e-value: 1.5E-12
score: 47.0
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 384..488
e-value: 6.0E-17
score: 61.3
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 11..113
e-value: 6.4E-11
score: 41.7
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 198..304
e-value: 1.4E-14
score: 53.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 114..197
e-value: 3.1E-11
score: 42.6
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 316..389
e-value: 6.1E-7
score: 29.3
coord: 395..483
e-value: 3.0E-6
score: 27.1
coord: 203..301
e-value: 8.0E-9
score: 35.4
NoneNo IPR availablePFAMPF13927Ig_3coord: 21..96
e-value: 2.8E-7
score: 30.9
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 140..347
e-value: 2.2E-9
score: 33.9
coord: 346..675
e-value: 1.0E-17
score: 61.5
coord: 1..164
e-value: 2.8E-5
score: 20.3
coord: 665..833
e-value: 2.3E-38
score: 129.9
NoneNo IPR availableGENE3D3.30.200.20coord: 553..655
e-value: 3.4E-18
score: 65.0
NoneNo IPR availableGENE3D1.10.510.10coord: 656..832
e-value: 9.4E-38
score: 129.4
NoneNo IPR availableCDDcd00096Igcoord: 218..298
e-value: 6.52508E-5
score: 40.9355
NoneNo IPR availableCDDcd00096Igcoord: 324..387
e-value: 5.49099E-7
score: 47.0987
NoneNo IPR availableCDDcd00096Igcoord: 39..107
e-value: 2.71157E-7
score: 47.8691
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 694..706
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 576..604
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 127..196
score: 8.593
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 311..389
score: 9.264
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 18..109
score: 9.228
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 413..482
score: 8.067
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 202..285
score: 9.627
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 321..390
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 119..200
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 24..108
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 395..484
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 203..302
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 570..834
score: 29.319
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 558..826

Blast
BLAST of TCONS_00004551-protein vs. Swiss-Prot (Human)
Match: PTK7 (Inactive tyrosine-protein kinase 7 OS=Homo sapiens GN=PTK7 PE=1 SV=2)

HSP 1 Score: 352.058 bits (902), Expect = 1.754e-106
Identity = 245/808 (30.32%), Postives = 383/808 (47.40%), Query Frame = 0
Query:   73 MSNNTLKITKVKRRHAGTYSCFAK-HKTEFRFAEFKVEIMYIQQANPLEPRKTYSGVEVEMQCIPPLGKPNPKPLWLKDG-KTFSDPRVDQSTFTLKISKTQLSDTANYTCVSMGYK-NRTTTASLTVYEKGPFSVKPEKINATEGDKVEFKCISGTKPPLPLKWFKRNKQCDDKGCKTLDEDVDLMSDVRFVKTDDGVLTITKVKPEDKADYVCTRFLGATTEEAVVKLHVITLIKIDLKPKASIDIDSTKPHTVACPYQGVNPKSISWIRKDTGALPSHMNVDGSTLVITKPQLSDSGVYTCKIV-GPLNSDEATVNLTMYKGLKFIKRPSNITGVVSKPLWIDCVGSGYPEPWVFYFRIGKGGGE-LNSTYFTTH----KNGTLYIPKLRKEDQGKYMCILKNDPGGSKTSQ----FELTVKSENEKAGASSP--MHRTIGIAVGCAGVYILLVIGLMIYCRAR-RARLLK----GIITEVDGEGKDPLI-GNGNKDI------------PLDDMKKFS---QWEYKRSGLEEIGTLGHGKMGRVYKANAVDIRPSEKRTLVAVKEFNSDEKEHKDEFNIEMEMFTQLDHINVVKLLGVCMNASPPDPWLLITDFGEEGDLKGYLDRNKN---------LSIHERLDMSMCVANGMDYLIAQHYMHRDLAARNCVVRANKSVSISFLSLCEDTYKDDYFSLNDYPVPLRWLSPECIQEENYSEKSDVWSFGITVWEIFSNGDRPYANFDNDAVLKGV-CLDLRLTKPKDCPDSIFHIMESCWLKEASERPSFADLKSAINDVKID 834
             +N +L +T+V+ R+AG Y C  +  +      E  + +  I+     EPR   +G E  + C+PP G P P   W   G +  +  RV Q    L ++    SD   YTC +      R    ++TV     +  KP+     EG      C++   P   + W+ RN+               +  D RF    +G L I  V+  D   Y C     A + EA  ++ V+  +K    P+    ++  K  TV C   G    +I W R D  +LP  +  +  TL   +    D+G YTC    GP     A V LT+   + F   P   T        + C   G P+P + +    KG    L+ T         +NG+L I  +  ED G+Y CI  N      T       +  V  E+E  G+  P  M +TIG++VG A  YI+ V+GLM YC+ R +A+ L+    G   E++     PL  G  + +I            P    K+ S   +  + RS L+ I TLG  + G V+ A A  +      TLV VK   S +++ + +F  E+EMF +L+H NVV+LLG+C  A   +P  ++ ++ + GDLK +L  +K+         LS  +++ +   VA GM++L    ++H+DLAARNC+V A + V +S L L +D Y  +Y+      VPLRW+SPE I E ++S KSDVW+FG+ +WE+F++G+ P+    +D VL  +     RL +P+ CP  ++ +M+ CW     +RPSF+++ SA+ D  +D
Sbjct:  281 FANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWY-RNQML-------------ISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW----KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREA---EPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVD 1067          

HSP 2 Score: 99.3673 bits (246), Expect = 3.112e-21
Identity = 118/485 (24.33%), Postives = 192/485 (39.59%), Query Frame = 0
Query:   25 SSAVAAVDSTLLVDCVTNPTDGVNVYWEKGGEAVPLQPTSGKEPEFFYMSNNTLKITKVKR-RHAGTYSCFAKHKT---EFRFAEFKVEIMYIQQANPLEPRKTYSGVEVEMQCIPPL-----GKPNPKPLWLKDGKTFSDPRVDQSTFTLKISKTQLS-------DTANYTCV---SMGYKNRTTTASLTVYEKGPFSV--KPEKINATEGDKVEFKCISGTKPPLPLKWFKRNKQCDDKGCKTLDEDVDLMSDVRFVKTDDGVLTITKVKPEDKADYVCTRFLGATTEEAVVKLHV-ITLIKIDLKP--KASIDIDSTKPHTVACPYQGVNPKSISWIRKDTGALPSHMNV--DGSTLVITKPQLSDSGVYTCKIVGPLNSDEATVNLTMYKGLKFIKRPSNITGVVSKPLWIDCVGSGYPEPWVFYFRIGKGGGELNSTYFTTHKNGTLYIPKLRKEDQGKYMCILKNDPGGSKTSQFELTV 483
            SS  A      L+ C       V+VYW   G   P+Q T     E  +   ++L    V R + +GT+ C A+      E R A     I +I+ A P+  +   S  E++ Q    L     G P P   W +DG   SD    QS  T+   +  L+        +  Y+C    + G    +   +L++ ++    V   P+ +     ++  F C    +PP  L+W       D+           L     F    +G L +T+V+P +   Y C   +G       + L   + L +I+  P  +  +    ++      P +G+   S+ W       LP+H  V   G  LV+     SD+GVYTC            VN+T+     ++K+P +      KP ++DC+    P+P V ++R      E   + F   KNGTL I  +   D   Y C + + P GS  +Q  + V
Sbjct:   39 SSQDALQGRRALLRCEVEAPGPVHVYWLLDG--APVQDT-----ERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE-AGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSD---GQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFE----DETPITNRSRPPHLRRATVFA---NGSLLLTQVRPRNAGIYRC---IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAGV-RLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE--DSRFEVFKNGTLRINSVEVYDGTWYRC-MSSTPAGSIEAQARVQV 498          
The following BLAST results are available for this feature:
BLAST of TCONS_00004551-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PTK71.754e-10630.32Inactive tyrosine-protein kinase 7 OS=Homo sapiens... [more]
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