TCONS_00003453-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00003453-protein
Unique NameTCONS_00003453-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length561

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00003453-protein ID=TCONS_00003453-protein|Name=TCONS_00003453-protein|organism=Clytia hemisphaerica|type=polypeptide|length=561bp
MAGKRGQAVAIQADVKTDEEWQKMLDTQGLMVVDVYAAWCGPCTAIVNTF
RRIKNETGDDLLHFAAAETDGIQELESYRGKSEPTFLFYGDGELINVIRG
CNGPVLNNYILTQLKKEHDILDGKAERTVFVDKALGGHHEDEKQDEESEV
IEEDEELARKMSRKIGKLPPLDNEVKSRTSTLAEVQIPKQVAVALIKPDA
VQAGLVDSIIEEIKANGLEILKQEEKVLSKEEAAEFYKQHEGSDHFEQLI
EFMSSGPCMTLVVSKPGDDTGEDLLPEFRALIGPLDVNMAKEEAPESLRA
KYGTDSIQNAVHSCDSSESAARELAFFFPDFNVPMVERMQKKKRLQRTLA
LIRPNALKKRRDSILKTIEDSGFLIAMQKEVHLERAQVEELYAEHKDQDY
FESLVTNMTCGPSLALCLAREDAVQTWRDMLGPKELVMPPSSQSERGEDQ
DGEDPPAPENQPSDLSLRKRFADPEDEINPLHGADTEEQVQREMNLFFPM
ETTVAVIKPDAYEKENERELIMSKIKEAGFKISAHKEVTLTKDLASMFYK
EHEGKDFFSSX
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001924XLOC_001924Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00003453TCONS_00003453Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001564Nucleoside_diP_kinase
IPR034907NDK-like_dom
IPR013766Thioredoxin_domain
IPR017937Thioredoxin_CS
IPR012336Thioredoxin-like_fold
Vocabulary: Biological Process
TermDefinition
GO:0006228UTP biosynthetic process
GO:0006241CTP biosynthetic process
GO:0006165nucleoside diphosphate phosphorylation
GO:0006183GTP biosynthetic process
GO:0045454cell redox homeostasis
Vocabulary: Molecular Function
TermDefinition
GO:0004550nucleoside diphosphate kinase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0045454 cell redox homeostasis
biological_process GO:0006241 CTP biosynthetic process
biological_process GO:0006183 GTP biosynthetic process
biological_process GO:0006165 nucleoside diphosphate phosphorylation
biological_process GO:0006228 UTP biosynthetic process
molecular_function GO:0004550 nucleoside diphosphate kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001564Nucleoside diphosphate kinasePRINTSPR01243NUCDPKINASEcoord: 192..214
score: 40.46
coord: 309..328
score: 49.76
IPR001564Nucleoside diphosphate kinaseSMARTSM00562ndk_5coord: 189..335
e-value: 1.1E-52
score: 191.0
coord: 345..505
e-value: 4.7E-33
score: 125.8
IPR001564Nucleoside diphosphate kinasePFAMPF00334NDKcoord: 346..500
e-value: 3.7E-28
score: 98.1
coord: 501..560
e-value: 5.5E-12
score: 45.8
coord: 192..331
e-value: 3.9E-37
score: 127.2
IPR034907Nucleoside diphosphate kinase-like domainGENE3D3.30.70.141coord: 186..337
e-value: 1.8E-46
score: 157.2
coord: 342..500
e-value: 1.1E-35
score: 122.1
IPR034907Nucleoside diphosphate kinase-like domainGENE3D3.30.70.141coord: 501..561
e-value: 3.1E-14
score: 52.6
IPR034907Nucleoside diphosphate kinase-like domainSUPERFAMILY54919Nucleoside diphosphate kinase, NDKcoord: 500..560
IPR034907Nucleoside diphosphate kinase-like domainSUPERFAMILY54919Nucleoside diphosphate kinase, NDKcoord: 345..499
IPR034907Nucleoside diphosphate kinase-like domainSUPERFAMILY54919Nucleoside diphosphate kinase, NDKcoord: 187..332
IPR013766Thioredoxin domainPFAMPF00085Thioredoxincoord: 15..104
e-value: 6.7E-11
score: 42.0
IPR013766Thioredoxin domainPROSITEPS51352THIOREDOXIN_2coord: 1..116
score: 8.67
NoneNo IPR availableGENE3D3.40.30.10coord: 7..164
e-value: 4.2E-17
score: 61.7
NoneNo IPR availableCDDcd04416NDPk_TXcoord: 190..328
e-value: 2.25893E-50
score: 170.083
NoneNo IPR availableCDDcd04416NDPk_TXcoord: 346..498
e-value: 3.65758E-43
score: 150.053
NoneNo IPR availableCDDcd02948TRX_NDPKcoord: 12..113
e-value: 2.13177E-48
score: 163.275
IPR017937Thioredoxin, conserved sitePROSITEPS00194THIOREDOXIN_1coord: 32..50
IPR012336Thioredoxin-like foldSUPERFAMILY52833Thioredoxin-likecoord: 14..115

Blast
[Close]
BLAST of TCONS_00003453-protein vs. Swiss-Prot (Human)
Match: TXND3 (Thioredoxin domain-containing protein 3 OS=Homo sapiens GN=NME8 PE=2 SV=2)

HSP 1 Score: 282.722 bits (722), Expect = 7.638e-88
Identity = 192/579 (33.16%), Postives = 292/579 (50.43%), Query Frame = 0 
Query:    1 MAGKRGQAVAIQADVKTDEEWQKMLDTQGLMVVDVYAAWCGPCTAIVNTFRRIKNETGDD-LLHFAAAETDGIQELESYRGKSEPTFLFYGDGELINVIRGCNGPVLNNYILTQLKKEHDILDGKAERTVFVDKALGGHHEDEKQDEESEVIEEDEELARKMSRKIGKLPPLDNEVKSRTSTLAEVQIPKQVAVALIKPDAVQAGLVDSIIEEIKANGLEILKQEEKVLSKEEAAEFYKQHEGSDHFEQLIEFMSSGPCMTLVVSK------------PGDDT-----GEDLLPEFRALIGPLDVNMAKEEAPESLRAKYGTDSIQNAVHSCDSSESAARELAF---FFPDFNVPMVERMQKKKRLQRTLALIRPNALKKRRDSILKTIEDSGFLIAMQKEVHLERAQVEELYAEHKDQDYFESLVTNMTCGPSLALCLAREDAVQTWRDMLGPKELVMPPSSQSERGEDQDGEDPPAPENQPSDLSLRKRFADPEDEINPLHGADTEEQVQREMNLFFPMETTVAVIKPDAYEKENERELIMSKIKEAGFKISAHKEVTLTKDLASMFYKEHEGKDFF 558
            MA K+ + V +Q  +     W +ML  +GL V+DVY AWCGPC A+   FR++KNE  +D +LHFA AE D I  L+ +R K EP FLF  +G++I  I+G N P++N  ++  + +E  I  G+  R  + +  L         D +SEV EE                       S   ++ E+      ++A+IKPDAV +  V  I  +I   G  I  + + VL++E+   FY +      FE+ + FM+SG    LVVS+            P  DT      ED  PE  A + P  +   ++   E L         Q+    CD  E AA    F   FFPDF      +  K  +L++TLAL+RPN   +R+D +L+ I+D  F I  Q++V L   + + L  E++++DYF  L+ NMT GPSLAL L R++ +Q W+ +LGP+ +                    A E  P   SL  +FA     +N L+G+D+ E  +RE+  FFP+++T+ +IKP A  +  +RE I+  +KEAGF ++  K++ LT +     Y +  GKDF+
Sbjct:    1 MASKKRE-VQLQTVINNQSLWDEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTLQPFRDKCEPVFLFSVNGKIIEKIQGANAPLVNKKVINLIDEERKIAAGEMARPQYPEIPLV--------DSDSEVSEE-----------------------SPCESVQEL-----YSIAIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVSFMTSGLSYILVVSQGSKHNPPSEETEPQTDTEPNERSED-QPEVEAQVTPGMMKNKQDSLQEYLER-------QHLAQLCDIEEDAANVAKFMDAFFPDF------KKMKSMKLEKTLALLRPNLFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLIENMTSGPSLALVLLRDNGLQYWKQLLGPRTV------------------EEAIEYFPE--SLCAQFAMDSLPVNQLYGSDSLETAEREIQHFFPLQSTLGLIKPHATSE--QREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFY 506

HSP 2 Score: 145.591 bits (366), Expect = 2.514e-37
Identity = 88/262 (33.59%), Postives = 151/262 (57.63%), Query Frame = 0 
Query:  192 AVALIKPDAVQAGLVDSIIEEIKANGLEILKQEEKVLSKEEAAEFYKQHEGSDHFEQLIEFMSSGPCMTLVVSKPGDDTGEDLLPEFRALIGPLDVNMAKEEAPESLRAKYGTDSIQ-NAVHSCDSSESAARELAFFFPDFNVPMVERMQKKKRLQRTLALIRPNALKKRRDSILKTIEDSGFLIAMQKEVHLERAQVEELYAEHKDQDYFESLVTNMTCGPSLALCLAREDAVQTWRDMLGPKE-----LVMPPSSQSERG 447
             +AL++P+       D ++  IK    +IL+Q + VLS++EA    K++E  D+F +LIE M+SGP + LV+ +   D G   L  ++ L+GP  V  A E  PESL A++  DS+  N ++  DS E+A RE+  FFP               LQ TL LI+P+A  ++R+ ILK ++++GF +   K++ L   Q+E++Y +   +D+++ L+  ++ GPS+ + L + +AV  WR ++GP +     L+ P S +++ G
Sbjct:  318 TLALLRPNLFHER-KDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLIENMTSGPSLALVLLR---DNG---LQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSDSLETAEREIQHFFP---------------LQSTLGLIKPHATSEQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIRAQFG 557
The following BLAST results are available for this feature:
BLAST of TCONS_00003453-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TXND37.638e-8833.16Thioredoxin domain-containing protein 3 OS=Homo sa... [more]
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