TCONS_00003006-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00003006-protein
Unique NameTCONS_00003006-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1951

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00003006-protein ID=TCONS_00003006-protein|Name=TCONS_00003006-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1951bp
MRVDDLKGKLNIATGNQTISNVKTNPEVDRKLRISISKNDEVVHITTLGD
FSKSCVSHVAKALLLLSTNKMAMTEMEKEHNSMQNGHIPTIPKVVTEIEK
LNARNHLRNTEIVDDNDNDEPLLCSEKQLESGKKILQDNEDIDDELQEKA
ISASRDGRFLKFDEEVGRGAFKTVYKGLDTETGVAVAWCELQDRKLSRSE
RARFKEEADLLKTLQHPNIVKFHDYWEITSSLKNGTKERKLILVTELMTS
GTLKTYIKRFTVVKEKILINWCRQILKGLNFLHTRVPAIIHRDLKCDNIF
ITGTTGLLKLGDLGLATFKKASFVKSVIGTPEFMAPEMYEERYDESVDVY
AFGMCMLEMASGEYPYMECQNPAQIYRRVTSGVPPESLNKVQSEELRKLI
VGCTKKEKSERLTIKDLIESEFLQAEKLRVELTKAISDIVDENLSVLPLR
LKGQRTNHSQDEAIEFDYKIDEDVPETLASEMVKSNHIQEDDMKNVVKAI
RNAVSSYNREKEKIQAAERRSREDSNVGVSESEDNGQVQQQQQPPAVSSS
QSTTSAVSSSTDVAAEVTQGGGNTNNGGGGGGEVKTLTAELELETLQQSE
PQPPVTNQTVTDVASRERTQSTSVSNTAAAAPEKVESNPSTEHVPQEGRQ
SPAESLQTTINTTESVTAETTSQQSNTTAESATQQSQQGRTSPPLGQSSQ
SNKKGKTKKGKLPKLSLQCVRDDTVAECSFDTHTGNRITFQFGIKEDSPE
DISQKMIEHEHLREINKELFVNQMNEIIAAVERGEVGPCNEPNKTSEDDP
QQEHTHTHTQKGNLSVDSGVQASGESGNELSEDSTAQDSISSFSSLSESE
SSITRSEVIQSKARLPNFADDVDMPDISPKTSSTDAPTAIPENDVSPHTP
PVEPGSPVKPPKGGVGRFNVQKVINSDIPKAVDTVPSLTASPRGRFSVQK
VQSDDLATPTTSPRSDTYASVVASSQEPATLQKDRSATLTPQSSLEKSDA
SIVAKADSNEDVVANKTKTSDAVSSKPVEQTKSSPSNSPSLSRHNSQLDQ
TSLQTQDKSISRVNSTVMEFDPLVEGQVLSPSAADTPAATTTTVASSSTA
AVSQSQEPPATRPDSASNSFNNSRCNSRTGSPIMNVTPSGXEDSTAQDSI
SSFSSLSESESSITRSEVIQSKARLPNFADDVDMPDISPKTSSTDAPTAI
PENDVSPHTPPVEPGSPVKPPKGGVGRFNVQKVINSDIPKAVDTVPSLTA
SPRGRFSVQKVQSDDLATPTTSPRSDTYASVVASSQEPATLQKDRSATLT
PQSSLEKSDASIVAKADSNEDVVANKTKTSDAVSSKPVEQTKSSPSNSPS
LSRHNSQLDQTSLQTQDKSISRVNSTVMEFDPLVEGQVLSPSAADTPAAT
TTTVASSSTAAVSQSQEPPATRPDSASNSFNNSRCNSRTGSPIMNVTPSG
SLENIKQYAIAQPPITGSTSIMASLKRDEPLQSRPPAPARSLSSSFTQQQ
LQQQMQQNKQQPQQPQQQMNNKQPQQQQQQQSAAGHAIPEPLLQAVVFSE
DYAKIKSKHRREMTELQKRHNDEYAKLMLKVRTLQPENTTAVPDSSRDTG
EASMQSKRRDEAEHQERRTISRHGSQELLDYQPNESSKKDKKDSTTENSR
KIDLEEMYKQQLDLMGIKQDSKAPKPDVKPSKPSLNELKLKKQAEQMNTK
QSGATTNDTSTERIGGDRTPTPQRKVSVPTIPSQNNQQNETNFFDSLTGL
NLSQLLHQYEVKERRNKSKTAPVQSAALMAAVAEASQTNQQQQHVTIGQT
THYNTIGASDSHVTWTHNNGQILQTPSEQHPHESQQQFYQNLFQQKQQQQ
QMLQTQQLTTTTCPQQTHEQAFPPGGAAGPNMMSSSWPNSGQSMFTNRSQ
SLNHLDSIPTQPGAVNAQQYATHQQGGNTASQHPQHQPNQHNNTPVNPGN
S
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001646XLOC_001646Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00003006TCONS_00003006Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR024678Kinase_OSR1/WNK_CCT
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004674protein serine/threonine kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 497..520
NoneNo IPR availableGENE3D3.10.20.90coord: 428..551
e-value: 1.0E-14
score: 54.2
coord: 714..817
e-value: 1.7E-10
score: 40.7
NoneNo IPR availableGENE3D1.10.510.10coord: 267..427
e-value: 1.4E-42
score: 144.5
NoneNo IPR availableGENE3D3.30.200.20coord: 124..266
e-value: 1.2E-26
score: 92.6
NoneNo IPR availableGENE3D1.10.510.10coord: 1232..1536
e-value: 0.01
score: 14.4
NoneNo IPR availableCDDcd13983STKc_WNKcoord: 158..423
e-value: 1.63103E-152
score: 470.555
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 160..423
e-value: 6.6E-63
score: 225.0
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 162..423
e-value: 3.2E-52
score: 177.4
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 160..423
score: 42.407
IPR024678Serine/threonine-protein kinase OSR1/WNK, CCT domainPFAMPF12202OSR1_Ccoord: 450..504
e-value: 4.7E-10
score: 39.4
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 289..301
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 162..424

Blast
BLAST of TCONS_00003006-protein vs. Swiss-Prot (Human)
Match: WNK1 (Serine/threonine-protein kinase WNK1 OS=Homo sapiens GN=WNK1 PE=1 SV=2)

HSP 1 Score: 513.842 bits (1322), Expect = 2.736e-149
Identity = 239/384 (62.24%), Postives = 298/384 (77.60%), Query Frame = 0
Query:  137 QDNEDIDDELQEKAISASRDGRFLKFDEEVGRGAFKTVYKGLDTETGVAVAWCELQDRKLSRSERARFKEEADLLKTLQHPNIVKFHDYWEITSSLKNGTKERKLILVTELMTSGTLKTYIKRFTVVKEKILINWCRQILKGLNFLHTRVPAIIHRDLKCDNIFITGTTGLLKLGDLGLATFKKASFVKSVIGTPEFMAPEMYEERYDESVDVYAFGMCMLEMASGEYPYMECQNPAQIYRRVTSGVPPESLNKVQSEELRKLIVGCTKKEKSERLTIKDLIESEFLQAE-KLRVELTKAISDIVDENLSV-LPLR---LKGQRTNHSQDEAIEFDYKIDEDVPETLASEMVKSNHIQEDDMKNVVKAIRNAVSSYNREKEKIQ 515
            Q  +DI+ EL+ KA+  S DGRFLKFD E+GRG+FKTVYKGLDTET V VAWCELQDRKL++SER RFKEEA++LK LQHPNIV+F+D WE  S++K    ++ ++LVTELMTSGTLKTY+KRF V+K K+L +WCRQILKGL FLHTR P IIHRDLKCDNIFITG TG +K+GDLGLAT K+ASF KSVIGTPEFMAPEMYEE+YDESVDVYAFGMCMLEMA+ EYPY ECQN AQIYRRVTSGV P S +KV   E++++I GC ++ K ER +IKDL+   F Q E  +RVEL +   +   E +++ L LR   +K  +  +  +EAIEF + ++ DVPE +A EMV+S ++ E D K + KAI++ VS   R++E+ Q
Sbjct:  199 QQQDDIE-ELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWE--STVKG---KKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAE---EDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQ 573          
The following BLAST results are available for this feature:
BLAST of TCONS_00003006-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
WNK12.736e-14962.24Serine/threonine-protein kinase WNK1 OS=Homo sapie... [more]
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