TCONS_00002421-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00002421-protein
Unique NameTCONS_00002421-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1524

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00002421-protein ID=TCONS_00002421-protein|Name=TCONS_00002421-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1524bp
RNASSAHKEDMRGETLFLELRRLYHCAAYNCIISIISCTQVELKFYTGLL
FTENVAKGQFLLENLIDTDREYKFESVLNSHFDRKQTLSMLRRNKEDDGL
NDANTKSRSRGKANAGYLSTQFLMETSLSQDVNRFDFNDPIEAYSNYSTN
NIDSVPANSPDTTIVEDNTPLSPDSESSNNTSTLSPTSTLMEMDELNQHE
IMSILLSLIHHMKNKQIYKPPTDTQLTAQPPPPLPSWMVYLQKKLTARDT
HVNIKLFIAKLIINEPKIFEPYGTYWYPSLIDLILSSHIPGPPINYFTID
LVVVMLSWSKTNIPPDTVVSRNMCSSLLEYLIKYTHHTNRSVLKNNLQVI
KTLLQVWKDRLQIPYQLIHTFFNNQDSEKKDSSTGLQLLGLVIKADFSPF
APQSSAGLSKHEFFTNLTNCLHFKYKEVYATAAEVCGLALNYYQEHQEAN
ELEFLLGNVSQELSNHSKKNKDLLVLCVFHMQSYYPNIVDRYIAPLLYCV
TELYGVLRTNCIQALTSRVQHLTNEQHQEIYKQIQGKDLEGLLSHRDEEA
QSETIRLIHGMLPNLTTDQLSEVLPLIANLQQNEYTSVRELTYDVFIWIY
ENCREDESRKSVLQLSKEVLVLGINDSNTKLSLKVLNFWRDESNLPKETI
ERTIEVVRALYSSKTEREYLSYASNLIMQLTSLSPDYTLPLFPNGLDSDE
HFRNFNVNFSWQRQQTANLTPLFIATQRSTASQGSYSLTQKSQGEFMGIR
ATQTTFDFTQTQQKDNQTGSLNWMNPTVQVDSSLATLSNARQSSPTSILS
DTPMDIDSIDGRPINARRRPSQSQNPDKAADILRLKRKFLKDQMTRNQHF
AAIEIKRQKMREVAMERRKAAKDKKVSMYRKYRVGELPDIQIKHSELIVP
LQALSQLDSKMGTKLFTSVLNAIISNLPEKLDENSVDRVYRDLEQALDIM
LRSSTINESAFTSALQNLCYTNKQLKLEPGLISTSSTASMQQPVGILLLE
KQLLSNMGNGEKSAKRRRMESEKPEDVATWLEVSRLYESIDDFDWLRSVF
SSHVSQSETTKNALSAETQNNYELALSLYKKATEENMSNENTPTESEEEY
LDNARMRCYQNLCLWDKLKKFTTSSAAQLLDQDDSVGEGGSFDAMALWKD
DELQETHLPYYIQSNIKLLCQGKVDHVSDDFDSFITNSLKEGAPKEHLQG
KYSLQLALLNIFKDDLGAGEHFLNISSQQFLSEWSVLSTLVSASRQKKLE
QLQKIVELEEYISMRKANGHHQAKQVESLLNTWSNRLPSLKAPLHVWDDI
VMTRCSLIRKLKSANEDDLNLSKYLDGEETKNILFIADVARKQGNLAVCN
QYLKESYNGAISNDQTMNLSFQWRYIYSKLLCDKIKMVGDKRKEKDKLDD
LVSAFEQMEKCRQQHDSMSENTKVQYHLLLHKIWNHLTKVVKQSDDLFYT
ENEGRAISKLGQNCSSRNEFLSRADGLCKEHISQCLIISKELVTNDKESR
DVQVKAMIKMYQYSDDKLKSKGXL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001303XLOC_001303Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00002421TCONS_00002421Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR012582NUC194
IPR011989ARM-like
IPR003151PIK-rel_kinase_FAT
IPR011990TPR-like_helical_dom
IPR014009PIK_FAT
IPR016024ARM-type_fold
Vocabulary: Cellular Component
TermDefinition
GO:0005634nucleus
Vocabulary: Molecular Function
TermDefinition
GO:0004677DNA-dependent protein kinase activity
GO:0005524ATP binding
GO:0003677DNA binding
GO:0005515protein binding
GO:0005488binding
Vocabulary: Biological Process
TermDefinition
GO:0006303double-strand break repair via nonhomologous end joining
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006303 double-strand break repair via nonhomologous end joining
cellular_component GO:0005634 nucleus
molecular_function GO:0005524 ATP binding
molecular_function GO:0005488 binding
molecular_function GO:0003677 DNA binding
molecular_function GO:0004677 DNA-dependent protein kinase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR012582NUC194SMARTSM01344NUC194_2coord: 1..319
e-value: 2.5E-65
score: 233.0
IPR012582NUC194PFAMPF08163NUC194coord: 2..314
e-value: 2.5E-86
score: 290.2
IPR011989Armadillo-like helicalGENE3D1.25.10.10coord: 187..978
e-value: 9.6E-12
score: 43.9
IPR003151PIK-related kinase, FATPFAMPF02259FATcoord: 1207..1436
e-value: 5.7E-22
score: 78.3
IPR011990Tetratricopeptide-like helical domainGENE3D1.25.40.10coord: 1010..1431
e-value: 0.042
score: 13.1
IPR014009PIK-related kinasePROSITEPS51189FATcoord: 981..1524
score: 9.463
IPR016024Armadillo-type foldSUPERFAMILY48371ARM repeatcoord: 194..694
coord: 136..160

Blast
BLAST of TCONS_00002421-protein vs. Swiss-Prot (Human)
Match: PRKDC (DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3)

HSP 1 Score: 723.776 bits (1867), Expect = 0.000e+0
Identity = 475/1449 (32.78%), Postives = 772/1449 (53.28%), Query Frame = 0
Query:    6 AHKEDMRGETLFLELRRLYHCAAYNCIISIISCTQVELKFYTGLLFTENVAKGQFLLENLIDTDREYKFESVLNSHFDRKQTLSMLRRNKEDDGLNDANTKSRSRGKANAGYLST-QFLMETSLSQDVNRFDFNDPIEAYSNYSTNNIDSVPANSP-------DTTIVEDNTPLSPDSESSNNTSTLSPTSTLMEMDELNQHEIMSILLSLIHHMKNKQIYKPPTDTQLTAQPPPPLPSWMVYLQKKLTARDTHVNIKLFIAKLIINEPKIFEPYGTYWYPSLIDLILSSHIPGPPINYFTIDLVVVMLSWS----KTNIPPDTVVSRNMCSSLLEYLIKYTHHTNRSVLKNNLQVIKTLLQVWKDRLQIPYQLIHTFFNNQDSEKKDSSTGLQLLGLVIKADFSPFAPQSSAGLSKHEFFTNLTNCLHF-KYKEVYATAAEVCGLALNYYQEHQEANELEFLLGNVSQELSNHSKKNKDLLVLCVFHMQSYYPNIVDRYIAPLLYCVTELYGVLRTNCIQALTSRVQHLTNEQHQEIYKQIQGKDLEGLLSHRDEEAQSETIRLIHGMLPNLTTDQLSEVLPLIANLQQNEYTSVRELTYDVFIWIYENCREDESR-----KSVLQLSKEVLVLGINDSNTKLSLKVLNFWRDESNLPKETIERTIEVVRALYSSKTEREYLSYASNLIMQLTSLSPDYTLPLFPNGLDSDEHFRNFNVNFSWQRQQTANLTPLFIATQRSTAS------QGSYSLTQKSQGEFMGIRATQTTFDFTQTQQKDNQTGSLNWMNPTVQVDSSLATLSNARQSSPTSILSDTPMDIDSIDGRPINARRRPSQSQNPD-----------------KAA----DILRLKRKFLKDQMTRNQHFAAIEIKRQKMREVAMERRKAAKDKKVSMYRKYRVGELPDIQIKHSELIVPLQALSQLDSKMGTKLFTSVLNAIISNLPEKLDENSVDRVYRDLEQALDIMLRSSTINESAFTSALQNL-CYTNKQLKLEPGLISTSSTASMQQPVGILLLEKQLLSNMGNGEKSAKRRRMESEKPEDVATWLEVSRLYESIDDFDWLRSVFSSHVSQSETTKNALSAETQNNYELALSLYKKATEENMSNENTPTESEEEYLDNARMRCYQNLCLWDKLKKFTTSSAAQLLDQDDSVGEGGSFDAMALWKDDELQETHLPYYIQSNIKLLCQGKVDHVSDDFDSFITNSLKEGAPKEHLQGKYSLQLALLNIFKDDLGAGEHFLNISSQQFLSEWSVLSTLVSASRQKKLEQLQKIVELEEYISMRKANGHHQAK-QVESLLNTWSNRLPSLKA-PLHVWDDIVMTRCSLIRKLKS-----ANEDDLNLSKYLDGEETKNI---------------------LFIADVARKQGNLAVCNQYLKESYNGAISNDQTMNLSFQWRYIYSKL 1380
            A  E+M GE   LE RRLYHCAAYNC IS+I C   ELKFY G LF+E   K   + ENLID  R Y F   +    +RK+    +R+   +    D++  S         Y+S+  +L +++LS+++++FDF+  +++YS YS+   D  PA          D T+ +D   L                    EMDELN+HE M+ L +L+ HM       PP   + +   P  LPSWM +L  KL      +NI+LF+AKL+IN  ++F PY  +W   L+ L  S +  G  I+Y  +++V  +LSW+     T +P D V++    + LL +L+K+  H  R+V ++NL++IKTL++ WKD L IPY+LI   F+ +D   KD+S G+QLLG+V+  D  P+ PQ   G+   E+F  L N + F +YKEVYA AAEV GL L Y  E +   E E L   V+++L  H    +D  ++C+  +   +P + DR++  + + + + +GVL+T C++ +  RV+ +T     E+Y Q++ KD   ++ HRD+E Q   + +I+ M+P L   +L E+L  +     +  T+ RE  Y++ +WI++N R+ ES      + + +L+K+VL+ G+ D N  L L + NFW  E+ LP  T++R +  + +LYS K E  +LS A+N ++++TS+SPDY  P+F + L S+  F+ + ++  W+ + T  LTP+F+ TQ S  +      +GS S      G+   IRATQ   DFT TQ  D ++ S +W+       SS   L +    S  S+L            R    +R P +S  PD                 K A    D+LRL+R+F++DQ   +  +A   +  QK  +      K  +D +V +YR YR G+LPDIQIKHS LI PLQA++Q D  +  +LF+S+ + I+  + +    +  + + + L Q  +  L ++      F S +Q++ C     L L+P  +S    AS+QQPVGI LLE+ LL  +   E  AKR R ++  P DV  W+E+++LY SI ++D LR +F+S +   + T++AL AE +++Y  A   Y +A  +    +  PTE+E+++ + A + CY +L  W  L+  +T+S    +D ++        D   +W +   QET+LPY I+S +KLL QG+ D       +FI  ++     K  L+  YS +L+LL + +DD+   ++++    Q F+  +S +  L+  SR  KL+ +Q + E++E+IS     G+  ++  ++ LLNTW+NR P  K  P+++WDDI+  RC  + K++        ++ +N+ +  DG+ +  +                     + + D ARKQ N ++  + LKE +  + + D  +     W   Y +L
Sbjct: 1922 AFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPS---------YMSSLSYLADSTLSEEMSQFDFSTGVQSYS-YSSQ--DPRPATGRFRRREQRDPTVHDDVLEL--------------------EMDELNRHECMAPLTALVKHMHRS--LGPPQGEEDSV--PRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLA----NRLLNFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIVMANDLPPYDPQ--CGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILE-ESLCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEVVLCRVEGMT-----ELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVEFVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNTLDRLL-ALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL-SECEFQEYTIDSDWRFRSTV-LTPMFVETQASQGTLQTRTQEGSLSARWPVAGQ---IRATQQQHDFTLTQTADGRS-SFDWLT-----GSSTDPLVDHTSPSSDSLL--------FAHKRSERLQRAPLKSVGPDFGKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSELKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCLASLQQPVGIRLLEEALLRLL-PAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRGIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDCYNHLAEWKSLEYCSTAS----IDSENPP------DLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQ---SLLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLLHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDNSMNVDQ--DGDPSDRMEVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLLKELHKESKTRDDWL---VSWVQSYCRL 3283          
The following BLAST results are available for this feature:
BLAST of TCONS_00002421-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PRKDC0.000e+032.78DNA-dependent protein kinase catalytic subunit OS=... [more]
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