TCONS_00002229-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00002229-protein
Unique Name	TCONS_00002229-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	643

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00002229-protein ID=TCONS_00002229-protein|Name=TCONS_00002229-protein|organism=Clytia hemisphaerica|type=polypeptide|length=643bp
MKNVTSLTWISICILHFITAQQDAADKFLDKYNTEIIELIHNNKKLKYKT
FTDSTPEHEMAFKEDEGQFNHKLKGYQKAALRINLTNVDEQSKRQLMFIR
RSLTSSYDYINENIFNLKHEMQKAFQEAGMKNYQNTSINLGLGELNGIIA
HLNISVEEKLDVWKGFRDSIGPKVRKDFIEFVRLKNKAARENGFADAGEF
KRSSYEVDDLEEIAEKFWLELKPFYQELHAYVRFRMNQKFGDHIKKEEAM
PAHLLGNMWALTWDGIFDHFKPYPNEPELDVSKALRKKLTNTTMMFKMTE
DFFKSIGWPSLPSNFWENSVLSPPTDGKKVTCHPTAWDMFGKVNGEQDVR
LIMCASLFHPHFTTAHHEVGHIYYALLYWNLPFQFREGANPAFHEAVGDT
LSLSVQVPQHLYNVGILDEVSNSEEQDINFLLKTASDTVAFLPFAYIVDK
WMWNVYNGNIKPDEMNKKWWELRLKYQGVRPPVERSEKDFDPATKYHVTA
DVPFIRYFFAVILQFTFHKYACKAAGHKGHLHQCSIYNSTEAGKAFGDML
KLGRSKPWPEQLKQFTGSEELSADPFLDYFAPLRKWLKKQHTKHNYPIGW
DENPYGQEVKSEQVGNNGDLLMVNLVGLVLSVLFTVICVAGIR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_001179	XLOC_001179	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00002229	TCONS_00002229	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001548	Peptidase_M2

Vocabulary: **Molecular Function**
Term	Definition
GO:0008237	metallopeptidase activity
GO:0008241	peptidyl-dipeptidase activity

Vocabulary: **Cellular Component**
Term	Definition
GO:0016020	membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
cellular_component	GO:0016020	membrane
molecular_function	GO:0008237	metallopeptidase activity
molecular_function	GO:0008241	peptidyl-dipeptidase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001548	Peptidase M2, peptidyl-dipeptidase A	PRINTS	PR00791	PEPDIPTASEA	coord: 214..241 score: 42.26 coord: 466..493 score: 62.5 coord: 431..456 score: 50.96 coord: 390..410 score: 66.27 coord: 494..522 score: 52.01 coord: 248..269 score: 59.47 coord: 362..378 score: 53.92
IPR001548	Peptidase M2, peptidyl-dipeptidase A	PFAM	PF01401	Peptidase_M2	coord: 21..600 e-value: 2.1E-188 score: 627.5
IPR001548	Peptidase M2, peptidyl-dipeptidase A	CDD	cd06461	M2_ACE	coord: 28..590 e-value: 0.0 score: 744.386
None	No IPR available	GENE3D	1.10.1370.10		coord: 22..593 e-value: 7.3E-55 score: 186.0
None	No IPR available	SUPERFAMILY	55486	Metalloproteases ("zincins"), catalytic domain	coord: 25..601

Blast

[Close]

BLAST of TCONS_00002229-protein vs. Swiss-Prot (Human)
Match: ACE (Angiotensin-converting enzyme OS=Homo sapiens GN=ACE PE=1 SV=1)

HSP 1 Score: 454.521 bits (1168), Expect = 2.328e-145
Identity = 217/476 (45.59%), Postives = 306/476 (64.29%), Query Frame = 0

Query:  157 EEKLDVWKGFRDSIGPKVRKDFIEFVRLKNKAARENGFADAGEFKRSSYEVDDLEEIAEKFWLELKPFYQELHAYVRFRMNQKFG-DHIKKEEAMPAHLLGNMWALTWDGIFDHFKPYPNEPELDVSKALRKKLTNTTMMFKMTEDFFKSIGWPSLPSNFWENSVLSPPTDGKKVTCHPTAWDMFGKVNGEQDVRLIMCASLFHPHFTTAHHEVGHIYYALLYWNLPFQFREGANPAFHEAVGDTLSLSVQVPQHLYNVGILDEVSNSEEQDINFLLKTASDTVAFLPFAYIVDKWMWNVYNGNIKPDEMNKKWWELRLKYQGVRPPVERSEKDFDPATKYHVTADVPFIRYFFAVILQFTFHKYACKAAGHKGHLHQCSIYNSTEAGKAFGDMLKLGRSKPWPEQLKQFTGSEELSADPFLDYFAPLRKWLKKQHTKHNYPIGWDE-NPYGQEVKSEQVGNNGDLLMVNLVGLVL 630
            E+ L  W+G+RD  G  + + + ++V L N+AAR NG+ DAG+  RS YE   LE+  E+ + EL+P Y  LHAYVR  +++ +G  HI  E  +PAHLLGNMWA TW  I+D   P+P+ P +D ++A+ K+      MFK  +DFF S+G   +P  FW  S+L  PTDG++V CH +AWD +   NG +D R+  C ++       AHHE+GHI Y + Y +LP   REGANP FHEA+GD L+LSV  P+HL+++ +L     S+E DINFL+K A D +AF+PF+Y+VD+W W V++G+I  +  N++WW LRLKYQG+ PPV R++ DFDP  K+H+ + VP+IRYF + I+QF FH+  C+AAGH G LH+C IY S EAG+     +KLG S+PWPE ++  TG   +SA   L YF PL  WL+ ++  H   +GW + N      +SE  G   D   V+ +GL L
Sbjct:  781 EDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFY---NG-KDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSE--GPLPDSGRVSFLGLDL 1250

HSP 2 Score: 430.639 bits (1106), Expect = 2.028e-136
Identity = 208/518 (40.15%), Postives = 311/518 (60.04%), Query Frame = 0

Query:   88 VDEQSKRQLMFIRRSLTSSYDYINENIFN-LKHEMQKAFQEAGMKNYQNTSINLGLG-ELNGIIAHLNISVEEKLDVWKGFRDSIGPKVRKDFIEFVRLKNKAARENGFADAGEFKRSSYEVDDLEEIAEKFWLELKPFYQELHAYVRFRMNQKFGD-HIKKEEAMPAHLLGNMWALTWDGIFDHFKPYPNEPELDVSKALRKKLTNTTMMFKMTEDFFKSIGWPSLPSNFWENSVLSPPTDGKKVTCHPTAWDMFGKVNGEQDVRLIMCASLFHPHFTTAHHEVGHIYYALLYWNLPFQFREGANPAFHEAVGDTLSLSVQVPQHLYNVGILDEVSNSEEQDINFLLKTASDTVAFLPFAYIVDKWMWNVYNGNIKPDEMNKKWWELRLKYQGVRPPVERSEKDFDPATKYHVTADVPFIRYFFAVILQFTFHKYACKAAGHKGHLHQCSIYNSTEAGKAFGDMLKLGRSKPWPEQLKQFTGSEELSADPFLDYFAPLRKWLKKQHTKHNYPIGWDE 602
             D Q +R +  +R   +++        +N L   M + +  A +     T+    L  +L  I+A  + S    L  W+G+ ++ G  ++  + +F  L N+A +++GF D G + RS Y     E+  E  + +L+P Y  LHA+VR  +++++GD +I     +PAHLLG+MWA +W+ I+D   P+P++P LDV+  + ++  N T MF++ E+FF S+    +P  FWE S+L  P DG++V CH +AWD + +    +D R+  C  +     +T HHE+GHI Y L Y +LP   R GANP FHEA+GD L+LSV  P+HL+ +G+LD V+N  E DIN+LLK A + +AFLPF Y+VD+W W V++G   P   N  WW LR KYQG+ PPV R+E  FD   K+HV    P+IRYF + +LQF FH+  CK AG++G LHQC IY ST+AG     +L+ G S+PW E LK   G + L A P L YF P+ +WL++Q+ ++   +GW E
Sbjct:  113 TDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILAS-SRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNR----KDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPE 625

The following BLAST results are available for this feature:

BLAST of TCONS_00002229-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00002229-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACE	2.328e-145	45.59	Angiotensin-converting enzyme OS=Homo sapiens GN=A...	[more]

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TCONS_00002229-protein (polypeptide) - C. hemisphaerica