Conserved uncharacterized protein (polypeptide) - C. hemisphaerica

Overview
NameConserved uncharacterized protein
Unique NameTCONS_00001165-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1575

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00001165-protein ID=TCONS_00001165-protein|Name=Conserved uncharacterized protein|organism=Clytia hemisphaerica|type=polypeptide|length=1575bp
MGRVRMEEDVRIQLFQSIENNNLDGVIDCIEEGVNLEEADSHGQTPLIFA
AEKGHLEIVAELLNRNVDANAKDQDGWTPLIAASKEGHVDVVGVLLENAA
KYNIPDMGGWTPLVWAAYKGHTDVVHELLNYGANPEARGQHNMTALIWAS
GRGHTGVVSKLINRGAKAEVADKYGTTALIWACRKGHYEVIKMLLNAGAN
CNAVGTHGWTPIIMAAKGGYGDVLTLLLDESTNVNAVDHQGLSALGWAAK
EGYEELVGKLIGKGAFLNIPDNRGDSPLIIASKEGHASVVRTLVNAYAEI
EITDSDGKTALFHGVEKGHVAVVRELLLAGANTEVTNKEGETPLLRGAKR
KHTQCVKLLLEKGANPAITDKKGDTPLHIAIRNRFAGLCEALLNDQKNSK
ILHQPNKAGETPYSIDLQNKPSILPGFFQGQQVNHDFDKMDYCTQQELLL
ATISEYLMEPSFSTPLTLGMYSRWGTGKSTQLKRLVELLEEAKSSVPIIP
FRVTAPVVFMCILAAVILSVVFWIATDSWEVGVASAIVLVNVFLIFFVVA
RVTLISHSRGLRSAGEAMTNFIYRCVWFLKLIYCIPPSIQEVKPALPVHL
MTVDLTRSVLVGDNPMTSLVNFIRELNDSIEQNIGIVIPRLYRIFQSGPY
RTPSGGKSIFRTKWKKSCCCVPSFLISIVVFACLLVGLILYGAWKLNGPS
AAIAIQIACLCVLGGFLLANLLRFFIIIYCLVLPMKKRVNFVSTQAGIQE
ETFLSVVKQELDLCVDMLECLDGFAQRQTRIIVHIDLLESLEQQKVLGLI
DSLKFMISAPGHPFIFVLSVDPRLLIKAMDQSLTIVHGPVNAYDYLRNLV
DLPFYISEPSKTKVDGLVPLELRNILEDQQISDNEESELEWDDNADINGD
VISRVSLPRDQQKHDVIANGGNGHVPNGNGTVPKLRSVKFPPEQSGNDGC
TNNNESISEDISNMIRTNMNGNLNDIKRVMNVISLKARILKSSDIHFQLP
RLGIWVNMCDVWPHKASWFILLCMDVSLALPDKMSIRRLYNLLGYAMPMV
GDHEENTGNAANYFDTFLASHKPVINVADVRMFTPFLFYLDPTIRSLMID
YMVALKSGTISKNPSIAHQFSSRSNFPISPSDSSKFIWRGGIDEQYLSKM
TPEDVVSQLAEIEGIETSLVPSYRDRILENNINGRVLISCDMNELREAMQ
MKFGDWQLFKAWINSSRFKDNSSRSEKSYYRPSSRSANGDGSQSESIPGS
PKQSSVSSYNPTQKGTSRLPALNETPDSSSNQPYTSHSPRNSPLQSRTRS
GKQRKGGKSKTRSLESEGSSPLKGPSPNPTLQRSADSSFASTDADNRSQQ
LSSFSDNEPSSSRYVQRVGSNNRQVTRPKQYHQQPQRNRVPPIAGLDQGV
DSLERGTKPSDTWIGKNERSFNKTNDTISSTSSQEFIQTSFEKQEESLHQ
IKPWQLSDGDESCSERGNEIVETSFTSTHQKRHLTSGLRKETRPPSLSEV
PLPPASMLNESHEDYIDLENHDSEHDALLSSSPPTSLDRKNAFQNSARLR
GMSNYTTSTDSDRQYLVENNNVVDS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000633XLOC_000633Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00001165TCONS_00001165Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002110Ankyrin_rpt
IPR020683Ankyrin_rpt-contain_dom
IPR011646KAP_P-loop
IPR013761SAM/pointed
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002110Ankyrin repeatPRINTSPR01415ANKYRINcoord: 190..204
score: 37.08
coord: 43..58
score: 45.51
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 372..401
e-value: 1.0
score: 18.4
coord: 306..335
e-value: 0.015
score: 24.5
coord: 108..137
e-value: 2.8E-6
score: 36.8
coord: 141..170
e-value: 0.76
score: 18.8
coord: 240..269
e-value: 0.63
score: 19.1
coord: 75..104
e-value: 0.011
score: 24.9
coord: 207..236
e-value: 0.015
score: 24.4
coord: 174..203
e-value: 2.8E-7
score: 40.2
coord: 42..71
e-value: 9.9E-5
score: 31.7
coord: 273..302
e-value: 0.012
score: 24.8
coord: 339..368
e-value: 0.011
score: 24.9
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 174..206
score: 11.808
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 42..74
score: 13.117
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 108..140
score: 11.701
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 207..239
score: 10.873
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 273..305
score: 11.06
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 240..272
score: 9.751
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 75..107
score: 11.434
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 306..338
score: 10.766
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 141..173
score: 9.484
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 339..371
score: 11.541
NoneNo IPR availableGENE3D1.10.150.50coord: 1142..1228
e-value: 1.1E-5
score: 25.1
NoneNo IPR availablePFAMPF13637Ank_4coord: 342..392
e-value: 2.5E-8
score: 34.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1474..1507
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1525..1563
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1221..1431
NoneNo IPR availableCDDcd00204ANKcoord: 40..162
e-value: 1.0767E-39
score: 144.449
NoneNo IPR availableCDDcd00204ANKcoord: 268..393
e-value: 1.41886E-35
score: 132.507
NoneNo IPR availableCDDcd00204ANKcoord: 103..228
e-value: 5.60457E-39
score: 142.523
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 322..420
e-value: 1.5E-23
score: 82.5
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 3..114
e-value: 3.0E-32
score: 110.6
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 115..177
e-value: 9.6E-24
score: 83.6
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 178..243
e-value: 8.8E-24
score: 83.3
IPR020683Ankyrin repeat-containing domainPFAMPF12796Ank_2coord: 245..336
e-value: 1.3E-11
score: 44.8
coord: 113..203
e-value: 2.1E-17
score: 63.4
coord: 17..106
e-value: 3.5E-14
score: 53.0
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 244..321
e-value: 5.1E-23
score: 80.8
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 9..404
score: 106.913
IPR020683Ankyrin repeat-containing domainSUPERFAMILY48403Ankyrin repeatcoord: 16..404
IPR011646KAP family P-loop domainPFAMPF07693KAP_NTPasecoord: 451..989
e-value: 1.4E-38
score: 132.9
IPR013761Sterile alpha motif/pointed domainSUPERFAMILY47769SAM/Pointed domaincoord: 1151..1217

Blast
BLAST of Conserved uncharacterized protein vs. Swiss-Prot (Human)
Match: KDIS (Kinase D-interacting substrate of 220 kDa OS=Homo sapiens GN=KIDINS220 PE=1 SV=3)

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 382/1111 (34.38%), Postives = 623/1111 (56.08%), Query Frame = 0
Query:   18 IENNNLDGVIDCIEEGVNLEEADSHGQTPLIFAAEKGHLEIVAELLNRNVDANAKDQDGWTPLIAASKEGHVDVVGVLLENAAKYNIPDMGGWTPLVWAAYKGHTDVVHELLNYGANPEARGQHNMTALIWASGRGHTGVVSKLINRGAKAEVADKYGTTALIWACRKGHYEVIKMLLNAGANCNAVGTHGWTPIIMAAKGGYGDVLTLLLDESTNVNAVDHQGLSALGWAAKEGYEELVGKLIGKGAFLNIPDNRGDSPLIIASKEGHASVVRTLVNAYAEIEITDSDGKTALFHGVEKGHVAVVRELLLAGANTEVTNKEGETPLLRGAKRKHTQCVKLLLEKGANPAITDKKGDTPLHIAIRNRFAGLCEALLNDQKNSKILHQPNKAGETPYSIDLQNKPSILPGFFQGQQVN---HDFDKMDYCTQQELLLATISEYLMEPSFSTPLTLGMYSRWGTGKSTQLKRLVELLEEAKSSVPIIPFRVTAPVVFMCILAAVILSVVFWIATDSWEVGVASAIVLVNVFLIFFVVARVTLISHSRGLRSAGEA------MTNFIYRCVWF----LKLIYCIPPSI-QEVKPALPVHLMTVDLTRSVLVGDNPMTSLVNFIRELNDSIEQNIGIVIPRLYRIFQSGPYRTPSGGKSIFRTKWKKSCCCVPSFLISIVVFACLLVGLILYGAWKLNGPSAAI-AIQIACLCVLGGFLLANLLRFFIIIYCLVLPMKKRV-NFVSTQAGIQEETFLSVVKQELDLCVDMLECLDGFAQRQTRIIVHIDLLESLEQQKVLGLIDSLKFMISAPGHPFIFVLSVDPRLLIKAMDQSLTIV--HGPVNAYDYLRNLVDLPFYISEPSKTKVDGLVPLELRNILEDQQISDNEESELEWDDNADINGDVISRVSLPRDQQKHDVIANGGNGHVPNGNGTVPKLRSVKFPPEQSGNDGCTNNNESISEDISNMIRTN---MNGNLNDIKRVMNVISLKARILKSSDIHFQLPRLGIWVNMCDVWPHKASWFILLCMDVSLALPDKMSIRRLYNLLGYAMPMVGDHE---ENTGNAANYFDTFLASHKPVINVADVRMFTPFLFYLDPTIRSLMIDYMVA 1104
            +E  N+  +   +E+  +++E +  GQTPL+ AAE+G+LEIV EL+    + N +D D WT LI+ASKEGHV +V  LL+        DMGGWT L+WA YKG TDVV  LL++GANP   G +++  +IWA+GRGH  +V  L+  GAK   +DKYGTT L+WA RKGH E +K LL  GA+ +  G +  T +I+A KGGY   +  +L  + NVN  D  G +AL  A+KEG+ E+V  L+  G ++NIPD  GD+ LI A + GH  +VR L+  YA+I+I   D KTAL+  VEKG+  +VR++L    +TE+  K+GETPL++  K ++ + V+LLL+KGA  +  DKKGDTPLHIAIR R   L E LL + K+ ++L++PNKAGETPY+ID  ++ SIL   F  + ++    D D + Y    +L  + +++ L EP+   P+ +G+Y++WG+GKS  LK+L + ++          F+ +  +VF+ +L    L ++F        +G+A ++  + +  IFF+V          G R  GE+      ++  + R + +    LKL++  PP + ++   ALPV  +  D  R   VG    TSL   I  L+D+ E+  G +  RL+R+F++      + GK     KWKK+ CC+PSF+I + +  C++ G+ L   ++++     + A+ I+   V+G   + N   ++ ++  L+   +KR+ N  S    ++ E F+ V+K E++L   M + +D F Q QTR++V ID L++ EQ KVL ++D+++ + S    PFI + + DP ++IKA++Q+L  V     +N +DY+RN+V LP +++    +          R  L    ++     ++   D   I  D   RVS    Q     +   G+    N   T  + +  +    Q            +S D++ ++ T     + +   ++R++N++S+  R+L+++ I F   RL  W+N+ + WP++ SW IL  ++ +  +PD+M+++ +Y  +   +P   D E   E  G+  N F+ FL+S  PV+   DV++F P    LDP +R ++ D   A
Sbjct:   13 VEEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGY----DLYSSALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIEPLFQFSWLIVFLTLLLCGGLGLLFAFTVHP-NLGIAVSLSFLALLYIFFIVIYF-------GGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNPPELPEQTTKALPVRFLFTDYNRLSSVGGE--TSLAEMIATLSDACEREFGFLATRLFRVFKT----EDTQGKK----KWKKT-CCLPSFVIFLFIIGCIISGITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQVLDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSFTQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSK--GPFIAIFASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNA--------RKFL----VTSATNGDVPCSDTTGIQEDADRRVS----QNSLGEMTKLGSKTALNRRDTYRRRQMQRTITRQ------------MSFDLTKLLVTEDWFSDISPQTMRRLLNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLILY-LEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRN-FEVFLSSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAA 1068          
The following BLAST results are available for this feature:
BLAST of Conserved uncharacterized protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
KDIS0.000e+034.38Kinase D-interacting substrate of 220 kDa OS=Homo ... [more]
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