TCONS_00001125-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00001125-protein
Unique NameTCONS_00001125-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length579

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00001125-protein ID=TCONS_00001125-protein|Name=TCONS_00001125-protein|organism=Clytia hemisphaerica|type=polypeptide|length=579bp
MSFRSKERLLKLLPRRSPRLLAKSQSTSDISSSMVDLGLKGAKELHKSHS
MVRPGHSFRPVIMKKQKAKQKEEANKTKSLKRMRESAVSLRSIENVMPTP
MKRIKSSTSQKDIALKAIDAIKEHPPKKRFSTRVATFAKGLSPSNSFRRK
RYQDSKLPASRSFDNNENDKIDKITVKKSSEVQRSTSLRLPRNQTAANNV
FYQSQRKQRKTSCVTPARRRGSKLWVDSFEYDESDGWTPQQIKRQEAIYE
LYCGETDMVEDLKLLQEVYFNPVAKLKLLTEEDLASIFGNIQVLLPLHED
LVKRLEEVRTENGSIEEIGRILTEWIPTLRPYIPYCANQLQMKNMLLHKT
KENKHFSDFLQRCLESPFSRKLDLWSFLDSPRSKLVKYPLLISNMHKYTP
KEHPDNIILYQAIQELEVIIKEADKATGKSKSSFYKDRMYFLDEGDHREA
LSQAQVLLCHGSLKNKNGGKIEAFLFDTVFLITRPASRNGMEMYQVLSQP
LLTNDMEYANVSDGELRLGGSFRSSLTKGPTAKFAFRVNPKELTRGKSII
LQANDQHDKKQWLNALSKVASMPSKGDPS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000629XLOC_000629Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00001125TCONS_00001125Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000219DH-domain
IPR011993PH_dom-like
IPR001331GDS_CDC24_CS
IPR001849PH_domain
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO:0035556intracellular signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0005085guanyl-nucleotide exchange factor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005085 guanyl-nucleotide exchange factor activity
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 247..425
e-value: 9.2E-41
score: 151.4
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 248..422
e-value: 1.7E-35
score: 122.8
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 243..426
score: 29.485
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 228..430
NoneNo IPR availableGENE3D1.20.900.10coord: 221..438
e-value: 2.1E-49
score: 167.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 67..88
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 144..166
NoneNo IPR availableCDDcd00160RhoGEFcoord: 244..424
e-value: 2.68185E-36
score: 132.422
IPR011993PH domain-likeGENE3D2.30.29.30coord: 442..572
e-value: 3.6E-14
score: 52.4
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 444..569
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved sitePROSITEPS00741DH_1coord: 374..399
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 533..571
score: 8.035

Blast
[Close]
BLAST of TCONS_00001125-protein vs. Swiss-Prot (Human)
Match: ARHG8 (Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens GN=NET1 PE=1 SV=1)

HSP 1 Score: 340.887 bits (873), Expect = 8.202e-110
Identity = 162/376 (43.09%), Postives = 245/376 (65.16%), Query Frame = 0 
Query:  204 SQRKQRKTSCVTPARRRGSKLWVDSFEYDESDGWTPQQIKRQEAIYELYCGETDMVEDLKLLQEVYFNPVAKLKLLTEEDLASIFGNIQVLLPLHEDLVKRLEEVRTENGSIEEIGRILTEWIPTLRPYIPYCANQLQMKNMLLHKTKENKHFSDFLQRCLESPFSRKLDLWSFLDSPRSKLVKYPLLISNMHKYTPKEHPDNIILYQAIQELEVIIKEADKATGKSKSSFYKDRMYFLDEGDHREALSQAQVLLCHGSLKNKNGGKIEAFLFDTVFLITRPASRNGMEMYQVLSQPLLTNDMEYANVSDGELRLGGSFRSSLTKGPTAKFAFRVNPKELTRGKSIILQANDQHDKKQWLNAL-SKVASMPSKGDP 578
            +Q+   +++  TPA+RR S LW +  +    +  T ++I+RQEAIYE+  GE D++EDLKL ++ Y +P+ KL +++EE+L  IFG++   +PLHEDL+ R+ E    +G++E+IG IL  W+P L  Y  YC+NQL  K  LL + K++    DFLQRCLESPFSRKLDLWSFLD PRS+LVKYPLL+  + K+TPKEHPD  +L  AI  ++ ++ + +   G+S+  +Y D++ +LDE      +  ++VLLCHG L++K+G K+  FLF  + ++TRP +RN    YQV  QP+   ++   ++ DG++R+GGSFR + +    AK  FR+   + +  +S  LQAND   K+QW N + + +A   S G P
Sbjct:  135 AQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAK-ALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKLYIFLFQDILVLTRPVTRNERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHTLQANDVFHKQQWFNCIRAAIAPFQSAGSP 509
The following BLAST results are available for this feature:
BLAST of TCONS_00001125-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ARHG88.202e-11043.09Neuroepithelial cell-transforming gene 1 protein O... [more]
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