TCONS_00000886-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00000886-protein
Unique Name	TCONS_00000886-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	529

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00000886-protein ID=TCONS_00000886-protein|Name=TCONS_00000886-protein|organism=Clytia hemisphaerica|type=polypeptide|length=529bp
QGAPLQKEQKKGHIGCVGPIVMWITFYVFLFQTAFGDIKTYESLDEGEQR
LLKYLKNFSVNSRPVNISSTAVYVNVTMEIVRLDAVSEKGQSVRMKLHIN
YLWRNPYLVWNPLNYKGVSEVILPEGEIWIPPIRLFNEASKTQGEYNEDN
HARTVLLTNDGNCSLTYAQFFKSTCEIDVSDFPFDQQYCDMTFGSWSMDE
RLLQLRAVKEEAISEQLYKENGEWHLTEATLKTHDVRYPIHRHKHSTIKL
SILIKRKYIFFIMNLVVPCALIACMIFLVFVLPAKSGERISLGITVMLSM
AIFQELSSEKLPSSSDNYPLLGVYYTTSMFEIGIALVMNCFILNVYYRNY
EMQPWMRRLLFDKLARLVRIDIPHTRTQHYIDRMSTGQFRELNPLAETTL
NNTAHNAHNIDGESALGNGNGEMSYFPKSTLHREDTQTIQRKTKKFSVNQ
NGSSSDLTYTKSNLSAKISLSLSSDPSTRIEERKLLGEDWKTAARILDRC
MLAIAISVGVISALTIFMQAARFREMFIP

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_000521	XLOC_000521	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00000886	TCONS_00000886	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 127..138 score: 39.03 coord: 175..189 score: 51.37 coord: 252..264 score: 27.01 coord: 94..110 score: 19.03
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 36..263 e-value: 1.6E-50 score: 171.1
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 49..258 e-value: 4.2E-44 score: 150.5
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 50..257
None	No IPR available	GENE3D	1.20.58.390		coord: 264..526 e-value: 7.3E-35 score: 119.3
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 265..517 e-value: 8.3E-32 score: 111.0
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 259..521
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 175..189

Blast

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BLAST of TCONS_00000886-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 214.157 bits (544), Expect = 4.257e-63
Identity = 148/495 (29.90%), Postives = 249/495 (50.30%), Query Frame = 0

Query:   46 EGEQRLLKYL-KNFSVNSRPVNISSTAVYVNVTMEIVRLDAVSEKGQSVRMKLHINYLWRNPYLVWNPLNYKGVSEVILPEGEIWIPPIRLFNEASKTQGEYNEDNHARTVLLTNDGNCSLTYAQFFKSTCEIDVSDFPFDQQYCDMTFGSWSMDERLLQLRAVKEEAISEQLYKENGEWHLTEATLKTHDVRYPIHRHKHSTIKLSILIKRKYIFFIMNLVVPCALIACMIFLVFVLPAKSGERISLGITVMLSMAIFQELSSEKLPSSSDNYPLLGVYYTTSMFEIGIALVMNCFILNVYYR---NYEMQPWMRRLLFDKLARLVRIDIPHTRTQHYIDRMSTGQFRELNPL--AETTLNNTAHNAHNIDGESALGNGNGEMSYFPKSTLHREDTQTIQRKTKKFSVNQNGSSS----DLTYTKSNLSAKISLSLSS-----DPSTRIEERKLLGEDWKTAARILDRCMLAIAISVGVISALTIFMQAARFRE 525
            E E RL + L ++++   RPV   S  V ++  + + +L  V E  Q +   L +  +W +  L WNP +Y G   + +P  +IW P I L+N A    G++  D+  +  LL   G  +      FKS+C+IDV+ FPFD Q C M FGSWS D+  + L  +   +++ + Y E+GEW + +A    HD++Y      +  I  S+ I+R  +F+ +NL++PC LI+ +  LVF LP+  GE+++L I+V+LS+ +F  + +E +PS+S   PL+G Y   +M  + +++V+  F+LNV+YR    + M  W++ +  + L R++ +  P +         + G  ++  PL  AE +  N    A +   +      +G   Y      HR      + K   FS N   SSS    D   + S LS +I  ++ S     +      E K + +DWK  A ++DR  L +   V ++    +F+Q    RE
Sbjct:   33 EAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVDDKTKA-LLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPTS---------NEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGY----CHHR------RIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQPLMARE 503

The following BLAST results are available for this feature:

BLAST of TCONS_00000886-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00000886-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA3	4.257e-63	29.90	Neuronal acetylcholine receptor subunit alpha-3 OS...	[more]

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TCONS_00000886-protein (polypeptide) - C. hemisphaerica