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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00000846-protein ID=TCONS_00000846-protein|Name=TCONS_00000846-protein|organism=Clytia hemisphaerica|type=polypeptide|length=860bp
MRLSILVLFLVVFVVVYSKPNGSHKVEEVEKEDHLLERRGKKEKVKADKK
KEKEKAEKEKEKAQKEKEKQKEKAEKEKEKEKEKAEKEKEKAEKEKEKEA
EKLRKKLEKERKKAEKKEKWHKVEEMLANNEDLVVDDDDLEKHYPKKLKE
KKKKGKKVKKSEHDTFENNYGRYKNRTGISVMENLNAINNAHDQQLDEVD
MVDLRPPQSKRDAMRDQMYLWIDRVVPYVIDPALKDGTDTIVDAMNEIQS
ASCIQFVPYTGQSNWIKFVSSSGCWSSVGRKFWVSGYQELSLGSGCLFKG
IIIHELLHSLGFYHEQSRYDRDENVEIFWENIPETNQHNFDRQKELRVSG
LGTQYDAQSIMHYGKFAFAKDPSKPTIVKLSNPETSIGQRDHLSDTDKEQ
LNLLYSCTSKDKQGWSNWSEYGPCTKEGRRERSRFCMHPTDKTSCPNPTN
TMYLHYGVDTEVQTGCAYYQDGHWGRWSSWGSCSVTCAIGTKSRTRKCDD
PAPSTNGAPCKGLSVQSASCEMISCDAGPYDCTFEAETTPTCKWTKDLNA
DFQWRRHTGSTPSSSTGPSGDHTSGTGYYMYIESSSPAMVGYKARLVSPQ
IKAGVHCLAFWYNMYGFSTGSLNVYLEGSQEQLFTLSGDQLKDWHLKRLK
IDSAGEFKIVIEAVRGSSFQGDIAIDDIKVKDGPCFAPPTPLPTTTEETT
TTDPPTTTTEPPTTTEPPTTATSTTTPLPTTTTTELTTTPEPHIPEAVPV
GCYKDFGYIDSKRPFSKYKDLSSIVIWSADVEFAKNNFKDVVGNCSAYAR
ANGYQHFAIQYYYECWTGSNEDINYGRDGESVGCWPQVDQNAGPFLIGQD
YSNMVYRWED Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004222 | metalloendopeptidase activity |
| GO:0008237 | metallopeptidase activity |
| GO:0008270 | zinc ion binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006508 | proteolysis |
Vocabulary: Cellular Component
| Term | Definition |
|---|
| GO:0016020 | membrane |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006508 |
proteolysis |
| cellular_component |
GO:0016020 |
membrane |
| molecular_function |
GO:0004222 |
metalloendopeptidase activity |
| molecular_function |
GO:0008237 |
metallopeptidase activity |
| molecular_function |
GO:0008270 |
zinc ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 39..124 |
| None | No IPR available | PRINTS | PR01705 | TSP1REPEAT | coord: 472..485
score: 48.79
coord: 490..501
score: 42.56
coord: 509..520
score: 32.37 |
| None | No IPR available | GENE3D | 2.60.120.200 | | coord: 526..685
e-value: 2.6E-50
score: 170.2 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 686..744 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 24..102 |
| None | No IPR available | SUPERFAMILY | 55486 | Metalloproteases ("zincins"), catalytic domain | coord: 216..407 |
| IPR001506 | Peptidase M12A | PRINTS | PR00480 | ASTACIN | coord: 241..259
score: 29.65
coord: 393..406
score: 39.88
coord: 315..332
score: 51.67
coord: 354..369
score: 49.48
coord: 296..314
score: 54.04 |
| IPR001506 | Peptidase M12A | PFAM | PF01400 | Astacin | coord: 220..408
e-value: 6.2E-58
score: 195.5 |
| IPR006026 | Peptidase, metallopeptidase | SMART | SM00235 | col_5 | coord: 217..359
e-value: 8.8E-34
score: 128.2 |
| IPR000998 | MAM domain | SMART | SM00137 | MAM_2 | coord: 527..687
e-value: 5.5E-51
score: 185.4 |
| IPR000998 | MAM domain | PFAM | PF00629 | MAM | coord: 532..686
e-value: 1.3E-42
score: 145.3 |
| IPR000998 | MAM domain | PROSITE | PS50060 | MAM_2 | coord: 530..687
score: 36.537 |
| IPR000998 | MAM domain | CDD | cd06263 | MAM | coord: 532..685
e-value: 1.54172E-45
score: 160.236 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SMART | SM00209 | TSP1_2 | coord: 415..467
e-value: 4.4
score: 3.6
coord: 474..526
e-value: 1.8E-12
score: 57.5 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | GENE3D | 2.20.100.10 | | coord: 470..525
e-value: 5.8E-14
score: 51.6 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | GENE3D | 2.20.100.10 | | coord: 409..454
e-value: 6.0E-4
score: 19.7 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PFAM | PF00090 | TSP_1 | coord: 416..449
e-value: 0.0098
score: 16.0
coord: 476..525
e-value: 4.2E-9
score: 36.4 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PROSITE | PS50092 | TSP1 | coord: 471..526
score: 12.996 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SUPERFAMILY | 82895 | TSP-1 type 1 repeat | coord: 469..525 |
| IPR024079 | Metallopeptidase, catalytic domain | GENE3D | 3.40.390.10 | | coord: 212..408
e-value: 2.0E-55
score: 187.3 |
| IPR034035 | Astacin-like metallopeptidase domain | CDD | cd04280 | ZnMc_astacin_like | coord: 223..405
e-value: 4.55421E-74
score: 240.551 |
| IPR013320 | Concanavalin A-like lectin/glucanase domain | SUPERFAMILY | 49899 | Concanavalin A-like lectins/glucanases | coord: 529..685 |
Blast
BLAST of TCONS_00000846-protein vs. Swiss-Prot (Human)
Match: MEP1A (Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE=1 SV=2) HSP 1 Score: 160.229 bits (404), Expect = 1.175e-40 Identity = 91/229 (39.74%), Postives = 132/229 (57.64%), Query Frame = 0
Query: 183 ENLNAINNAHDQQLDEVDMVDLRPPQSKRDAMRDQMYLWIDRVVPYVIDPALK-DGTDTIVDAMNEIQSASCIQFVPYTGQSNWIKFVSSSGCWSSVGRKFWVSGYQELSLGSGCLFKGIIIHELLHSLGFYHEQSRYDRDENVEIFWENIPETNQHNFDRQKELRVSGLGTQYDAQSIMHYGKFAFAKDPSKPTI-VKLSNPETSIGQRDHLSDTDKEQLNLLYSCTS 409
++++ IN A L + D++ Q R+ +RD W +PY++ L + I+ A + SC+ F PY G+S++I F GCWS VG + Q +S+G GC +K II HE+LH+LGFYHEQSR DRD+ V I+W+ I QHNFD + ++ L T YD +S+MHY F+F K+ S PTI K+ + IGQR S D E+LN +Y+CT+
Sbjct: 41 KDISEINLAAGLDLFQGDIL----LQKSRNGLRDPNTRWT-FPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQ---HVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTT 261
The following BLAST results are available for this feature:
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