TCONS_00000746-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00000746-protein
Unique NameTCONS_00000746-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length749

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00000746-protein ID=TCONS_00000746-protein|Name=TCONS_00000746-protein|organism=Clytia hemisphaerica|type=polypeptide|length=749bp
MKLKIVVKISLLLGQIYGPVLSFHDLRNGGDSQSLANFTADLHITSSDSD
TCPYSHIVTCGFMENYLQKDFSGVTFYNQSSHFLFSNHTIKDLQDINSRL
IITYGKCSGFHGFYVIVAERNYGYEHAPCFLLSIETQFINDILQQIDWFN
HAILHLNPVFLDLLLAYSSQYPNLHFVHFYLLWSIKERDFDELKEKFMFL
RLERINSADFEQSLDRYVLDFQYQKINLQSGTNNNKSRHVEDAKQNRLSI
LRPNQSRKKKHAILSQKITIRVATVFFKPLVFEFIDNSTTNQNGVCFKGH
NCRIPVVQDETNHKTRIGCCIGYFIDVFNLLERKMGFTYELYVVPDGAYG
ALIDGRWNGMIGELVAGRADVALQSLSVTYQRQRVVDFVPYLLTSNFGLI
RSISRTDQKQSFKIRWDFATALSTMLAASFLCATILVIVFLYVHENLLHW
LFAANVYFPIGEIFTYTLGLAFQRDMGALNPRQWSGRLVALGYAAAMTVF
MSAYTAKICASSIDNQPLDDFKGFSGPEFQNPSNSYKIGTITGRGQSQEE
YFKNHNLEQYRKMHDFMLENSVQSDEEALEKILNGTLQAHIIEVTSVVQG
LASKLSRHCDKVTVYEENLGQHELTFAYAKGFTYGKQISDTLQRMKDREK
FEPIRKKWIQESFCFTKVVSQQFEWTYFSGILVIMGISLVLSMLIVLVEN
LYVHFGLKNALDQKKRRGSLQNGASSYKQAVISKTSNLPYSADNNAIIW
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000464XLOC_000464Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00000746TCONS_00000746Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR019594Glu/Gly-bd
IPR001320Iontro_rcpt
Vocabulary: Molecular Function
TermDefinition
GO:0005234extracellular-glutamate-gated ion channel activity
GO:0004970ionotropic glutamate receptor activity
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016020 membrane
molecular_function GO:0005234 extracellular-glutamate-gated ion channel activity
molecular_function GO:0004970 ionotropic glutamate receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domainSMARTSM00918Lig_chan_Glu_bd_2coord: 305..366
e-value: 8.1E-19
score: 78.5
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domainPFAMPF10613Lig_chan-Glu_bdcoord: 310..391
e-value: 3.9E-21
score: 75.3
IPR001320Ionotropic glutamate receptorSMARTSM00079GluR_14coord: 301..661
e-value: 4.3E-6
score: -12.8
NoneNo IPR availableGENE3D3.40.190.10coord: 511..619
e-value: 6.6E-11
score: 42.0
NoneNo IPR availableGENE3D3.40.190.10coord: 265..433
e-value: 1.4E-24
score: 85.7
NoneNo IPR availableSUPERFAMILY53850Periplasmic binding protein-like IIcoord: 269..404
coord: 525..663

Blast
[Close]
BLAST of TCONS_00000746-protein vs. Swiss-Prot (Human)
Match: NMDE4 (Glutamate receptor ionotropic, NMDA 2D OS=Homo sapiens GN=GRIN2D PE=1 SV=2)

HSP 1 Score: 138.658 bits (348), Expect = 1.661e-33
Identity = 123/467 (26.34%), Postives = 214/467 (45.82%), Query Frame = 0 
Query:  270 IRVATVFFKPLVFEFIDNSTTNQNGVCFKGH-NCRIPV------VQDETNHKTRIGCCIGYFIDVFNLLERKMGFTYELYVVPDGAYGALIDGRWNGMIGELVAGRADVALQSLSVTYQRQRVVDF-VPYLLTSNFGLIRSISRTDQKQSFKIRWDFATALSTMLAASFLCATILVIVFLYV-----HENLLHWLFAANVYFPIGEIFTYTLGLAFQRDMGALNPRQWSGRLVALGYAAAMTVFMSAYTAKICASSIDNQPLDDFKGFSGPEFQNPSNSY---KIGTITGRGQSQEEYFKNHNLEQYRKMHDFMLENSVQSDEEALEKILNGTLQAHIIEVTSVVQGLASKLSRHCDKVTVYEENL-GQHELTFAYAKGFTYGKQISDTLQRMKDREKFEPIRKKWIQESFCFT---KVVSQQFEWTYFSGILVIMGISLVLSMLIVLVENLYVHFGLKNALDQKKR 716
            + VAT+  +P V   I       +G C +    CR  +        D    + R  CC G+ ID+   L   +GF+Y+LY+V +G +G  IDG WNGMIGE+   RAD+A+ SL++  +R  +VDF VP++ T    ++   + T    +F   +  A  +  M         + V +F Y+     + +L          F IG+       L F   +   NPR  + +++ L +A    +F+++YTA + A  I  + +D   G S  +FQ P   Y   K GT+   G +++    N     Y  MH +M+  +    EEAL ++  G L A I +  +V+  +A K    C  VT+    +        A  KG  + + I   L +    ++ E + + W+    C     +V+S + +    +G+  ++ +++ LS+L+   E+L V++ L++ L    R
Sbjct:  432 LTVATLEERPFV---IVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKR--CCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWV-MMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVP-NGSTEKNIRSN-----YPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDA-AVLNYMARK-DEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLS-GICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHL-VYWRLRHCLGPTHR 882
The following BLAST results are available for this feature:
BLAST of TCONS_00000746-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NMDE41.661e-3326.34Glutamate receptor ionotropic, NMDA 2D OS=Homo sap... [more]
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